Study of PPCPs in Eastern Asian countries
| Project/Area Number |
21406005
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 海外学術 |
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| Research Field |
Environmental pharmacy
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| Research Institution | Hiroshima International University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
OHTA Shigeru 広島大学, 大学院・医歯薬学総合研究科, 教授 (60160503)
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| Co-Investigator(Renkei-kenkyūsha) |
KITAMURA Shigeyuki 日本薬科大学, 薬学部, 教授 (40136057)
NISHIJIMA Wataru 広島大学, 環境安全センター, 教授 (20243602)
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|---|
| Project Period (FY) |
2009 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥17,160,000 (Direct Cost: ¥13,200,000、Indirect Cost: ¥3,960,000)
Fiscal Year 2011: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2010: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2009: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
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| Keywords | 環境汚染 / 医薬品 / 東アジア / 生態毒性 / 医薬品汚染 / 大韓民国 / 生態系毒性 / 環境動態 / 環境保全リーダー育成 |
|---|
| Research Abstract |
The aquatic environmental pollution by the pharmaceuticals has been investigated in Eastern Asian countries. The studies were carried out as joint research with local universities in Indonesia, Airlangga University and South Korea, Pusan University. Some pharmaceuticals were detected in the local rivers and effluent of sewage treatment plants. The reseach cooperation was developed.
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Report
(4 results)
Research Products
(62 results)
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[Journal Article] Prediction of in vive hepatic clearance and half-life of drug candidates in human using chimeric mice with humanized liver2012
Author(s)
Sanoh, Seigo ; Horiguchi, Aya ; Sugihara, Kazumi ; Kotake, Yaichiro ; Tayama, Yoshitaka ; Ohshita, Hiroki ; Tate noo, Chise ; Horie, Toni ; Kitamura, Shigeyuki ; Ohta, Shigeru
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Journal Title
Drug Metabolism & Disposition
Volume: 40(2)
Pages: 322-328
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[Journal Article] Activation of morphine glucuronidation by fatty acyl-CoAs and its plasticity : a comparative study in humans and rodents including chimeric mice carrying human liver2010
Author(s)
Nurrochmad, Ariel ; Ishii, Yuji ; Nakanoh, Hitomi ; Inoue, Tae ; Horie, Torn ; Sugihara, Kazumi ; Ohta, Shigeru ; Taketomi, Akinobu ; Maehara, Yoshihiko ; Yamada, Hideyuki
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Journal Title
Drug Metabolism and Pharmacokinetics
Volume: 25(3)
Pages: 262-373
NAID
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[Journal Article] Disruption of thyroid hormone function by environmental pollutants2009
Author(s)
Kashiwagi, Keiko ; Furuno, Nobuaki ; Kitamura, Shigeyuki ; Ohta, Shigeru ; Sugihara, Kazumi ; Utsumi, Kozo ; Hanada, Hideki ; Taniguchi, Kikuyo ; Suzuki, Ken-ichi ; Kashiwagi, Akihiko
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Journal Title
Journal of Health Science
Volume: 55(2)
Pages: 147-160
NAID
Related Report
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[Journal Article] Nuclear hormone receptor activity of polybrominated diphenyl ethers and their hydroxylated and methoxylated metabolites in transactivation assays using Chinese hamster ovary cells2009
Author(s)
Kojima, Hiroyuki, Takeuchi, Shinji, Uramaru, Naoto, Sugihara, Kazumi, Yoshida, Takahiko, Kitamura, Shigeyuki
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Journal Title
Environmental Health Perspectives 17(8)
Pages: 1210-1218
Related Report
Peer Reviewed
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[Journal Article] Disruption of thyroid hormone function by environmental pollutants2009
Author(s)
Kashiwagi, Keiko, Furuno, Nobuaki, Kitamura, Shigeyuki, Ohta, Shigeru, Sugihara, Kazumi, Utsumi, Kozo, Hanada, Hideki, Taniguchi Kikuyo, Suzuki, Ken-ichi, Kashiwagi, Akihiko
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Journal Title
Journal of Health Science 55(2)
Pages: 147-160
NAID
Related Report
Peer Reviewed
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[Book] Endocrine Disruption in Toxic Responses. In Ballantyne Bryan(ed), the 3rd Edition of General and Applied Toxicology2009
Author(s)
Kitamura, Shigeyuki, Sugihara, Kazumi, Nakamura, Kazuo, Yaichiro Kotake, Kashiwagi, Akihiko, Fujimoto, Nariaki
Total Pages
15
Publisher
Johan Wiley and Sons Ltd
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