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Study of PPCPs in Eastern Asian countries

Research Project

Project/Area Number 21406005
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section海外学術
Research Field Environmental pharmacy
Research InstitutionHiroshima International University

Principal Investigator

SUGIHARA Kazumi  広島国際大学, 薬学部, 准教授 (20271067)

Co-Investigator(Kenkyū-buntansha) OHTA Shigeru  広島大学, 大学院・医歯薬学総合研究科, 教授 (60160503)
Co-Investigator(Renkei-kenkyūsha) KITAMURA Shigeyuki  日本薬科大学, 薬学部, 教授 (40136057)
NISHIJIMA Wataru  広島大学, 環境安全センター, 教授 (20243602)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥17,160,000 (Direct Cost: ¥13,200,000、Indirect Cost: ¥3,960,000)
Fiscal Year 2011: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2010: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2009: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
Keywords環境汚染 / 医薬品 / 東アジア / 生態毒性 / 医薬品汚染 / 大韓民国 / 生態系毒性 / 環境動態 / 環境保全リーダー育成
Research Abstract

The aquatic environmental pollution by the pharmaceuticals has been investigated in Eastern Asian countries. The studies were carried out as joint research with local universities in Indonesia, Airlangga University and South Korea, Pusan University. Some pharmaceuticals were detected in the local rivers and effluent of sewage treatment plants. The reseach cooperation was developed.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (62 results)

All 2012 2011 2010 2009 2008

All Journal Article (21 results) (of which Peer Reviewed: 8 results) Presentation (36 results) Book (5 results)

  • [Journal Article] Prediction of in vive hepatic clearance and half-life of drug candidates in human using chimeric mice with humanized liver2012

    • Author(s)
      Sanoh, Seigo ; Horiguchi, Aya ; Sugihara, Kazumi ; Kotake, Yaichiro ; Tayama, Yoshitaka ; Ohshita, Hiroki ; Tate noo, Chise ; Horie, Toni ; Kitamura, Shigeyuki ; Ohta, Shigeru
    • Journal Title

      Drug Metabolism & Disposition

      Volume: 40(2) Pages: 322-328

    • Related Report
      2011 Final Research Report
  • [Journal Article] Effects of Polybrominated Diphenyl Ethers(PBDEs) and Their Derivatives on Protein Disulfide Isomerase Activity and Growth Hormone Release of GH3 Cells2012

    • Author(s)
      Hashimoto, Shako ; Yoshimura, Hiromi ; Okada, Kazushi ; Uramaru, Naoto ; Sugihara, Kazumi ; Kitamura, Shigeyuki ; Imaoka, Susumu
    • Journal Title

      Chemical Research in Toxicology

      Volume: 25(3) Pages: 656-663

    • Related Report
      2011 Final Research Report
  • [Journal Article] An improved thyroid hormone reporter assay to determine the thyroid hormone-like activity of amiodarone, bithionol, closantel and rafoxanide2012

    • Author(s)
      Matsubara, Kana ; Sanoh, Seigo ; Ohta, Shigeru ; Kitamura, Shigeyuki ; Sugihara, Kazumi ; Fujimoto, Nariaki
    • Journal Title

      Toxicology Letters

      Volume: 208(1) Pages: 30-35

    • Related Report
      2011 Final Research Report
  • [Journal Article] Effects of Polybrominated Diphenyl Ethers (PBDEs) and Their Derivatives on Protein Disulfide Isomerase Activity and Growth Hormone Release of GH3 Cells2012

    • Author(s)
      Hashimoto S, Yoshimura H, Okada K, Uramaru N, Sugihara K, Kitamura S
    • Journal Title

      Chem Res Toxicol

      Volume: (in press)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Prediction of in vivo hepatic clearance and half-life of drug candidates in human using chimeric mice with humanized liver2012

    • Author(s)
      Sanoh S, Horiguchi A, Sugihara K, Kotake Y, Tayama Y, Ohshita H
    • Journal Title

      Drug Metab Dispos

      Volume: 40 Pages: 322-328

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] An improved thyroid hormone reporter assay to determine the thyroid hormone-like activity of amiodarone, bithionol, closantel and rafoxanide2012

    • Author(s)
      Matsubara K, Sanoh S, Ohta S, Kitamura S, Sugihara K, Fujimoto N
    • Journal Title

      Toxicol Lett

      Volume: 208 Pages: 30-35

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of tea beverages on aldehyde oxidase activity2011

    • Author(s)
      Tayama, Yoshitaka ; Sugihara, Kazumi ; Sanoh, Seigo ; Miyake, Katsushi ; Marita, Shushi ; Kitamura, Shigeyuki ; Ohta, Shigeru
    • Journal Title

      Drug Metabolism and Pharmacokinetics

      Volume: 26(1) Pages: 94-101

    • NAID

      130004463166

    • Related Report
      2011 Final Research Report
  • [Journal Article] Effect of tea beverages on aldehyde oxidase activity2011

    • Author(s)
      Tayama Y, Sugihara K, Sanoh S, Miyake K, Morita S, Kitamura S, Ohta
    • Journal Title

      Drug Metab Pharmacokinet

      Volume: 26 Pages: 94-101

    • NAID

      130004463166

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Activation of morphine glucuronidation by fatty acyl-CoAs and its plasticity : a comparative study in humans and rodents including chimeric mice carrying human liver2010

    • Author(s)
      Nurrochmad, Ariel ; Ishii, Yuji ; Nakanoh, Hitomi ; Inoue, Tae ; Horie, Torn ; Sugihara, Kazumi ; Ohta, Shigeru ; Taketomi, Akinobu ; Maehara, Yoshihiko ; Yamada, Hideyuki
    • Journal Title

      Drug Metabolism and Pharmacokinetics

      Volume: 25(3) Pages: 262-373

    • NAID

      10027582853

    • Related Report
      2011 Final Research Report
  • [Journal Article] Activation of morphine glucuronidation by fatty acyl-CoAs and its plasticity : a comparative study in humans and rodents including chimeric mice carrying human liver.2010

    • Author(s)
      Nurrochmad A, Ishii Y, Nakanoh H, Inoue T, Horie T, Sugihara K, Ohta S, Taketomi A, Maehara Y, Yamada H
    • Journal Title

      Drug Metab Pharmacokinet.

      Volume: 25(3) Pages: 262-273

    • NAID

      10027582853

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of tea beverages on aldehyde oxidase activity.2010

    • Author(s)
      Tayama Y, Sugihara K, Sanoh S, Miyake K, Morita S, Kitamura S, Ohta S
    • Journal Title

      Drug Metab Pharmacokinet.

      Volume: 26(1) Pages: 94-101

    • NAID

      130004463166

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 在宅で発生する向精神薬等取扱注意医薬品の残薬処理の実態調査2010

    • Author(s)
      杉原数美
    • Journal Title

      有害・医療廃棄物研究

      Volume: 22(2) Pages: 82-85

    • Related Report
      2010 Annual Research Report
  • [Journal Article] Nuclear hormone receptor activity of polybrominated diphenyl ethers and their hydroxylated and methoxylated metabolites in transactivation assays using Chinese hamster ovary cells2009

    • Author(s)
      Kojima, Hiroyuki ; Takeuchi, Shinji ; Uramaru, Naoto ; Sugihara, Kazumi ; Yoshida, Takahiko ; Kitamura, Shigeyuki
    • Journal Title

      Environmental Health Perspectives

      Volume: 117(8) Pages: 1210-1218

    • Related Report
      2011 Final Research Report
  • [Journal Article] Current situation of drug information in the kindergarten and nursery teacher : a pilot study2009

    • Author(s)
      Tayama, Yoshitaka ; Miyake, Katsushi ; Kanazawa, Erl ; Kaneko, Tetuo ; Sugihara, Kazumi ; Toyomi, Atsushi ; Marita, Shushi ; Kobayashi, Masao ; Ohta, Shigeru
    • Journal Title

      Yakugaku Zasshi

      Volume: 129(5) Pages: 617-622

    • NAID

      130000136166

    • Related Report
      2011 Final Research Report
  • [Journal Article] Prediction of human disposition toward S3Hwarfarin using chimeric mice with humanized liver2009

    • Author(s)
      Inoue, Tae ; Sugihara, Kazumi ; Ohshita, Hiroki ; Horie, Torn ; Kitamura, Shigeyuki ; Ohta, Shigeru
    • Journal Title

      Drug Metabolism and Pharmacokinetics

      Volume: 24(2) Pages: 153-160

    • NAID

      10025723190

    • Related Report
      2011 Final Research Report
  • [Journal Article] Modulation of connexin 43 in rotenoneinduced model of Parkinson's disease2009

    • Author(s)
      Kawasaki, A.; Hayashi, T.; Nakachi, K.; Trosko, J. E.; Sugihara, K.; Kotake, Y.; Ohta, S
    • Journal Title

      Neuroscience

      Volume: 160(1) Pages: 61-68

    • Related Report
      2011 Final Research Report
  • [Journal Article] Disruption of thyroid hormone function by environmental pollutants2009

    • Author(s)
      Kashiwagi, Keiko ; Furuno, Nobuaki ; Kitamura, Shigeyuki ; Ohta, Shigeru ; Sugihara, Kazumi ; Utsumi, Kozo ; Hanada, Hideki ; Taniguchi, Kikuyo ; Suzuki, Ken-ichi ; Kashiwagi, Akihiko
    • Journal Title

      Journal of Health Science

      Volume: 55(2) Pages: 147-160

    • NAID

      110007161008

    • Related Report
      2011 Final Research Report
  • [Journal Article] Nuclear hormone receptor activity of polybrominated diphenyl ethers and their hydroxylated and methoxylated metabolites in transactivation assays using Chinese hamster ovary cells2009

    • Author(s)
      Kojima, Hiroyuki, Takeuchi, Shinji, Uramaru, Naoto, Sugihara, Kazumi, Yoshida, Takahiko, Kitamura, Shigeyuki
    • Journal Title

      Environmental Health Perspectives 17(8)

      Pages: 1210-1218

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Disruption of thyroid hormone function by environmental pollutants2009

    • Author(s)
      Kashiwagi, Keiko, Furuno, Nobuaki, Kitamura, Shigeyuki, Ohta, Shigeru, Sugihara, Kazumi, Utsumi, Kozo, Hanada, Hideki, Taniguchi Kikuyo, Suzuki, Ken-ichi, Kashiwagi, Akihiko
    • Journal Title

      Journal of Health Science 55(2)

      Pages: 147-160

    • NAID

      110007161008

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 広島県内における在宅医療廃棄物の発生・回収・廃棄に関する調査2009

    • Author(s)
      杉原数美, 等
    • Journal Title

      有害・医療廃棄物研究 21

      Pages: 23-23

    • NAID

      40017216811

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Study on the pharmaceuticals in hospital sewage and their toxicities in the aquatic environment2008

    • Author(s)
      Sugihara, Kazumi
    • Journal Title

      Yakugaku Kenkyu no Shinpo

      Volume: 25 Pages: 99-105

    • Related Report
      2011 Final Research Report
  • [Presentation] 水環境中医薬品類の太陽光および紫外線による分解と毒性変動調査2012

    • Author(s)
      川畑公平、尾川雄一、杉厘数圭、佐能正剛、北村繁幸、太田茂
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      札幌市
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 釜山市(大韓民国)の市街地を流域とする温泉川での医薬品汚染調査2012

    • Author(s)
      杉原数美、川畑公平、Moon Jeon-Ok, 佐能正剛、北村繁幸、太田茂
    • Organizer
      第46回日本水環境学会年会
    • Place of Presentation
      東京都
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 釜山市街を流域とする中規模河川の医薬品汚染調査2011

    • Author(s)
      杉原数美、川畑公平、Moon Jeon-Ok, 佐能正剛、北村繁幸、太田茂
    • Organizer
      フォーラム2011 :衛生薬学・環境トキシコロジーシンポジウム
    • Place of Presentation
      金沢市
    • Related Report
      2011 Final Research Report
  • [Presentation] 医薬品等の特定汚染源物質による河川汚染濃度予測マップツールの作成2011

    • Author(s)
      内田博久, 川畑公平, 尾川雄一, 佐能正剛, 北村繁幸, 太田茂, 杉原数美
    • Organizer
      フォーラム2011 :衛生薬学・環境トキシコロジーシンポジウム
    • Place of Presentation
      金沢市
    • Related Report
      2011 Final Research Report
  • [Presentation] 紫外線照射による水環境中医薬品類の分解および水生生物への毒性変動調査2011

    • Author(s)
      川畑公平、雌、尾川雄一、佐能正剛、北村繁幸、太田茂
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡市
    • Related Report
      2011 Final Research Report
  • [Presentation] ポテンシャルマップを用いた生活排水流入河川の医薬品汚染濃度予測2011

    • Author(s)
      杉厘数圭、尾川雄一、川畑公平、佐能正剛、北杖繁圭、西嶋渉、太田茂
    • Organizer
      第45回日本水環境学会年会
    • Place of Presentation
      札幌市
    • Related Report
      2011 Final Research Report
  • [Presentation] 釜山市街を流域とする中規模河川の医薬品汚染調査2011

    • Author(s)
      杉原数美、川畑公平、Moon Jeon-Ok, 太田茂
    • Organizer
      フォーラム2011・衛生薬学・環境トキシコロジーシンポジウム
    • Place of Presentation
      金沢市
    • Related Report
      2011 Annual Research Report
  • [Presentation] 水環境中医薬品類の紫外線による分解と毒性変動2011

    • Author(s)
      川畑公平、杉原数美、太田茂
    • Organizer
      フォーラム2011・衛生薬学・環境トキシコロジーシンポジウム
    • Place of Presentation
      金沢市
    • Related Report
      2011 Annual Research Report
  • [Presentation] 医薬品等の特定汚染源物質による河川汚染濃度予測マップツールの作成2011

    • Author(s)
      内田博久, 川畑公平, 尾川雄一, 佐能正剛, 北村繁幸, 太田茂, 杉原数美
    • Organizer
      フォーラム2011:衛生薬学・環境トキシコロジーシンポジウム
    • Place of Presentation
      金沢市
    • Related Report
      2011 Annual Research Report
  • [Presentation] 大韓民国釜山市温泉川の医薬品汚染調査2011

    • Author(s)
      杉原数美、川畑公平、Mon Jyoun、尾川雄一、佐能正剛、北村繁幸、太田茂
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡市(グランシップ静岡など)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 紫外線照射による水環境中医薬品類の分解および水生生物への毒性変動調査2011

    • Author(s)
      川畑公平、杉原数美、尾川雄一、佐能正剛、北村繁幸、太田茂
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡市(グランシップ静岡など)
    • Related Report
      2010 Annual Research Report
  • [Presentation] ポテンシャルマップを用いた生活排水流入河川の医薬品汚染濃度予測2011

    • Author(s)
      杉原数美、尾川雄一、川畑公平、佐能正剛、北村繁幸、西嶋渉、太田茂
    • Organizer
      第45回日本水環境学会年会
    • Place of Presentation
      札幌市(北海道大学)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 黒瀬川の水質汚染調査報告2010

    • Author(s)
      杉原数美
    • Organizer
      平成22年度東広島市公衆衛生協議会総会
    • Place of Presentation
      東広島市
    • Year and Date
      2010-04-22
    • Related Report
      2011 Final Research Report
  • [Presentation] 黒瀬川の水質汚染調査報告2010

    • Author(s)
      杉原数美
    • Organizer
      平成22年度東広島市公衆衛生協議会総会
    • Place of Presentation
      東広島市(福富道の駅)
    • Year and Date
      2010-04-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] 生活排水流入河川の生活関連物質汚染と流域住民への環境保全意識調査2010

    • Author(s)
      秋吉里絵、古道律子、宗重美恵子、尾川雄一、川畑公平、佐能正剛、太田茂、杉原数美
    • Organizer
      第49回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
    • Place of Presentation
      米子市
    • Related Report
      2011 Final Research Report
  • [Presentation] インドネシア・スラバヤ市スラバヤ川の医薬品汚染調査~アイルランガ大学との共同調査~2010

    • Author(s)
      杉原数美, 尾川雄一, 佐光華佳, Yuwano, A. H. Syahrani, M.佐能正剛, 北村繁幸, 太田茂
    • Organizer
      フォーラム2010衛生環境トキシコロジー
    • Place of Presentation
      東京
    • Related Report
      2011 Final Research Report
  • [Presentation] 下水道未整備地域河川での医薬品汚染ポテンシャルマップを用いた汚染予測と流域住民の環境保全意識調査,フォーラム2010衛生環境トキシコロジー2010

    • Author(s)
      秋吉里絵, 古道律子, 宗重美恵子, 杉原数美, 尾川雄一, 川畑公平, 佐能正剛, 北寸繁太田
    • Organizer
      フォーラム2010衛生環境トキシコロジー
    • Place of Presentation
      東京
    • Related Report
      2011 Final Research Report
  • [Presentation] 環境化学物質による甲状腺ホルモン応答の高感度評価2010

    • Author(s)
      松原加奈, 佐能正剛, 岩瀬恵理, 藤本成明, 浦丸直人, 杉原数美, 加藤善久, 北村繁幸, 太田茂
    • Organizer
      フォーラム2010衛生環境トキシコロジー
    • Place of Presentation
      東京
    • Related Report
      2011 Final Research Report
  • [Presentation] 生活排水流入モデル河川における医薬品環境負荷予測2010

    • Author(s)
      尾川雄一、杉原数美、川畑公平、佐光華佳、佐能正剛、北村繁幸、太田茂
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山市
    • Related Report
      2011 Final Research Report
  • [Presentation] 広島県内保険薬局を対象とした医薬品廃棄に関するパイロット調査2010

    • Author(s)
      杉原数美、尾川雄一、佐能正剛、北村繁幸、太田茂
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山市
    • Related Report
      2011 Final Research Report
  • [Presentation] 水環境中医薬品の紫外線による分解物生成と水棲生物毒性変動2010

    • Author(s)
      尾川雄一, 杉原数圭, 川畑公平, 佐光華佳, 佐能正剛, 北村繁幸, 太田茂
    • Organizer
      日本トキシコロジー学会
    • Place of Presentation
      宜野湾市
    • Related Report
      2011 Final Research Report
  • [Presentation] 生活排水流入河川の生活関連物質汚染と流域住民への環境保全意識調査2010

    • Author(s)
      秋吉里絵、古道律子、宗重美恵子、尾川雄一、川畑公平、佐能正剛、太田茂、杉原数美
    • Organizer
      第49回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
    • Place of Presentation
      米子市(米子コンベンションセンター)
    • Related Report
      2010 Annual Research Report
  • [Presentation] インドネシア・スラバヤ市スラバヤ川の医薬品汚染調査~アイルランガ大学との共同調査~2010

    • Author(s)
      杉原数美1, 尾川雄一, 佐光華佳, M.Yuwano, A.H.Syahrani, 佐能正剛, 北村繁幸, 太田茂
    • Organizer
      フォーラム2010衛生環境トキシコロジー
    • Place of Presentation
      東京都(星薬科大学)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 下水道未整備地域河川での医薬品汚染ポテンシャルマップを用いた汚染予測と流域住民の環境保全意識調査2010

    • Author(s)
      秋吉里絵, 古道律子, 宗重美恵子, 杉原数美, 尾川雄一, 川畑公平, 佐能正剛, 北村繁幸, 太田茂
    • Organizer
      フォーラム2010衛生環境トキシコロジー
    • Place of Presentation
      東京都(星薬科大学)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 環境化学物質による甲状腺ホルモン応答の高感度評価2010

    • Author(s)
      松原加奈, 佐能正剛, 岩瀬恵理, 藤本成明, 浦丸直人, 杉原数美, 加藤善久, 北村繁幸, 太田茂
    • Organizer
      フォーラム2010衛生環境トキシコロジー
    • Place of Presentation
      東京都(星薬科大学)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 水環境中医薬品の紫外線による分解物生成と水棲生物毒性変動2010

    • Author(s)
      尾川雄一, 杉原数美, 川畑公平, 佐光華佳, 佐能正剛, 北村繁幸, 太田茂
    • Organizer
      日本トキシコロジー学会
    • Place of Presentation
      宜野湾市(沖縄コンベンションセンター)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 生活排水流入河川での医薬品による水汚染調査2010

    • Author(s)
      杉原数美, 尾川雄一, 川畑公平, 佐光華佳, 佐能正剛, 太田茂, 西嶋渉, 北村繁幸
    • Organizer
      第44回日本水環境学会年会
    • Place of Presentation
      福岡市
    • Related Report
      2009 Annual Research Report
  • [Presentation] 生活排水流入モデル河川における医薬品環境負荷予測2010

    • Author(s)
      尾川雄一, 杉原数美, 川畑公平, 佐光華佳, 佐能正剛, 北村繁幸, 太田茂
    • Organizer
      日本薬学会 第130年会
    • Place of Presentation
      岡山市
    • Related Report
      2009 Annual Research Report
  • [Presentation] 広島県内保険薬局を対象とした医薬品廃棄に関するパイロット調査2010

    • Author(s)
      杉原数美, 尾川雄一, 佐能正剛, 北村繁幸, 太田茂
    • Organizer
      日本薬学会 第130年会
    • Place of Presentation
      岡山市
    • Related Report
      2009 Annual Research Report
  • [Presentation] HYDROXYLATED POLYBROMINATED DIPHENYL ETHERS INTERRACT WITH THYROID HORMONE AND ESTROGEN RECEPTORS2009

    • Author(s)
      Sugihara K, Kitamura S, Shinohara S, Iwase E, Uramaru N, Shigematsu H, Fujimoto N and Ohta S
    • Organizer
      DIOXIN2009
    • Place of Presentation
      北京市、中華人民共和国
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] 水環境中医薬品類の紫外線による分解と非意図的生成物の分析2009

    • Author(s)
      尾川雄一, 杉厘数圭, 佐能正剛, 北拉繁圭, 久保光志, 太田茂
    • Organizer
      フォーラム衛生薬学・環境トキシコロジー
    • Place of Presentation
      宜野湾市
    • Related Report
      2011 Final Research Report
  • [Presentation] 生活排水流入河川流域の医薬品汚染ポテンシャルマップーモデル河川黒瀬川での調査一2009

    • Author(s)
      杉原数美, 尾川雄一, 佐光華佳, 佐能正剛, 清水良, 北村繁幸, 太田茂
    • Organizer
      フォーラム衛生薬学・環境トキシコロジー
    • Place of Presentation
      宜野湾市
    • Related Report
      2011 Final Research Report
  • [Presentation] 水環境中医薬品類の紫外線による分解と毒性変動2009

    • Author(s)
      尾川雄一, 杉厘数圭, 佐能正剛, 北村繁圭, 久保光志, 太田茂
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Related Report
      2011 Final Research Report
  • [Presentation] 水環境中医薬品類の紫外線による分解と非意図的生成物の分析2009

    • Author(s)
      尾川雄一, 杉原数美, 佐能正剛, 北村繁幸, 久保光志, 太田茂
    • Organizer
      フォーラム衛生薬学・環境トキシコロジー
    • Place of Presentation
      沖縄県宜野湾市
    • Related Report
      2009 Annual Research Report
  • [Presentation] 生活排水流入河川流域の医薬品汚染ポテンシャルマップ-モデル河川 黒瀬川での調査-2009

    • Author(s)
      杉原数美, 尾川雄一, 佐光華佳, 佐能正剛, 清水良, 北村繁幸, 太田茂
    • Organizer
      フォーラム衛生薬学・環境トキシコロジー
    • Place of Presentation
      沖縄県宜野湾市
    • Related Report
      2009 Annual Research Report
  • [Presentation] ヒト肝キメラマウスを用いたヒト薬物代謝・動態予測2009

    • Author(s)
      杉原数美, 井上多恵, 田上千秋, 堀口彩, 佐能正剛, 立野知世, 堀江透, 北村繁幸, 太田茂
    • Organizer
      日本薬物動態学会第24回年会
    • Place of Presentation
      京都市
    • Related Report
      2009 Annual Research Report
  • [Book] Organophocphates as endocrine disruptors' in 'Anticholinesterase Pesticides'2011

    • Author(s)
      Kitamura, Shigeyuki; Sugihara, Kazumi; Fujimoto, Nariaki; Yamazaki, Takeshi
    • Publisher
      Wiley Edited by Satoh, Tetsuo : Gupta, Ramesh C
    • Related Report
      2011 Annual Research Report
  • [Book] Organophosphates as Endocrine Disruptor in Anticholinesterase pesticides2010

    • Author(s)
      Kitamura, S., Sugihara, K., Fujimoto, N., Yamazaki, T.
    • Related Report
      2011 Final Research Report
  • [Book] Organophosphates as Endocrine Disruptor, in Anticholinesterase pesticides.2010

    • Author(s)
      Kitamura, S., Sugihara, K., Fujimoto, N., Yamazaki, T.
    • Total Pages
      14
    • Publisher
      Johan Wiley and Sons Ltd.
    • Related Report
      2010 Annual Research Report
  • [Book] Endocrine Disruption in Toxic Responses. In Ballantyne Bryan(ed), the 3rd Edition of General and Applied Toxicology2009

    • Author(s)
      Kitamura, Shigeyuki ; Sugihara, Kazumi ; Nakamura, Kazuo ; Yaichiro Kotake ; Kashiwagi, Akihiko ; Fujimoto, Nariaki
    • Related Report
      2011 Final Research Report
  • [Book] Endocrine Disruption in Toxic Responses. In Ballantyne Bryan(ed), the 3rd Edition of General and Applied Toxicology2009

    • Author(s)
      Kitamura, Shigeyuki, Sugihara, Kazumi, Nakamura, Kazuo, Yaichiro Kotake, Kashiwagi, Akihiko, Fujimoto, Nariaki
    • Total Pages
      15
    • Publisher
      Johan Wiley and Sons Ltd
    • Related Report
      2009 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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