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Study on preventive effects of intake of a large amount of dairy products by Mongolians on cleft lip/palate incidence

Research Project

Project/Area Number 21406032
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section海外学術
Research Field Surgical dentistry
Research InstitutionAichi Gakuin University

Principal Investigator

NATSUME Nagato  愛知学院大学, 歯学部, 教授 (90183532)

Co-Investigator(Kenkyū-buntansha) SAKAI Eiko  愛知学院大学, 心身科学部, 教授 (80148254)
YAMANAKA Katsumi  名古屋学芸大学, 栄養学部, 教授 (40351209)
OTSUKA Takanobu  名古屋市立大学, 医学系・研究科, 教授 (10185316)
SENDA Akira  愛知学院大学, 歯学部, 歯学部 (80097584)
NAKAGAKI Haruo  愛知学院大学, 歯学部, 教授 (10097595)
KOJIMA Takashi  愛知学院大学, 歯学部, 教授 (70186675)
HATORI Masami  愛知学院大学, 歯学部, 教授 (50113072)
MAEDA Hatsuhiko  愛知学院大学, 歯学部, 教授 (30175591)
MORITA Ichizou  愛知学院大学, 歯学部, 教授 (50301635)
INOUE Makoto  愛知学院大学, 薬学部, 教授 (50191888)
YOSHIDA Waka  愛知学院大学, 歯学部, 助教 (10513210)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥7,670,000 (Direct Cost: ¥5,900,000、Indirect Cost: ¥1,770,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2009: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Keywordsモンゴル人 / 乳製品 / 予防 / 口唇裂 / 口蓋裂 / モンゴル
Research Abstract

We have investigated the incidence five times for three years in Mongolia. Besides, our Mongolian staff has investigated the incidence throughout the year. As the result
1.Mongolian incidence rate of cleft lip/palate was 0.07%(Japanese incidence is 0.2%).
2.We conducted studies on maternal environment of 961 Mongolian pregnant women.
3.We obtained 1, 999 samples for a repository of Mongolian cleft lip/palate genes.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (20 results)

All 2011 2010 2009

All Journal Article (12 results) (of which Peer Reviewed: 10 results) Presentation (8 results)

  • [Journal Article] 口唇・口蓋裂患者に関する疫学的研究(第50報)平成22年度モンゴル調査報告2011

    • Author(s)
      夏目長門, 吉田和加, 永田映里佳, 藤原久美子
    • Journal Title

      日本口蓋裂学会雑誌

      Volume: 36(2) Pages: 76-76

    • Related Report
      2011 Final Research Report
  • [Journal Article] 口唇・口蓋裂患者に関する疫学的研究(第49報)平成22年度モンゴル調査報告2011

    • Author(s)
      夏目長門, 吉田和加, 藤原久美子
    • Journal Title

      日本口腔科学会雑誌

      Volume: 60(3) Pages: 281-281

    • Related Report
      2011 Final Research Report
  • [Journal Article] 口蓋裂形成術後に認められた類比嚢胞および類表皮嚢胞に関する検討2011

    • Author(s)
      加藤大貴, 古川博雄, 南克浩, 新美照幸, 藤原久美子, 夏目長門
    • Journal Title

      日本口蓋裂学会雑誌

      Volume: 36(1) Pages: 7-11

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Epidemiological Analysis of Cleft Lip and/or palate by Cleft pattern2011

    • Author(s)
      Yoshikazu Nagase, Nagato Natsume, Tomoki Kato, Toko Hayakawa
    • Journal Title

      Journal of Maxillofacial and Oral Surgery

      Volume: 9(4) Pages: 389-95

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] 口唇・口蓋裂患者に関する疫学的研究(第49報)平成22年度モンゴル調査報告2011

    • Author(s)
      夏目長門
    • Journal Title

      日本口腔科学会雑誌

      Volume: 60巻3号 Pages: 281-281

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 口唇・口蓋裂患者に関する疫学的研究(第50報)モンゴル国における調査報告2011

    • Author(s)
      夏目長門
    • Journal Title

      日本口蓋裂学会雑誌

      Volume: 36巻2号 Pages: 76-76

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 口唇・口蓋裂患者に関する疫学的研究(第48報)モンゴル人における口唇口蓋裂発現率2010

    • Author(s)
      夏目長門
    • Journal Title

      日本口蓋裂学会雑誌

      Volume: 35(2) Pages: 137-137

    • Related Report
      2011 Final Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] RYK遺伝子変異は非症候群性の口唇裂・口蓋裂発症における遺伝要因のひとつである2010

    • Author(s)
      渡邊章, 秋田定伯, 夏目長門, 中野洋子, 内山健志, 吉浦孝一郎
    • Journal Title

      日本口蓋裂学会雑誌

      Volume: 35(1) Pages: 9-17

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] 口唇口蓋裂患者に認められた上唇部類皮嚢胞の1例2010

    • Author(s)
      加藤大貴, 外山佳孝, 石川拓, 井村英人, 阿知波学美, 鈴木聡, 新美照幸, 古川博雄, 藤原久美子, 秋山芳夫, 前田初彦, 夏目長門
    • Journal Title

      障害者歯科

      Volume: 31(2) Pages: 242-246

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Mutations in BMP4 are associated with subepithelial, microform, and overt cleft lip2009

    • Author(s)
      Suzuki S, Marazita ML, Cooper ME, Miwa N, Hing A, Juqessur A, Natsume N, Shimozato K, Ohbayashi N, Suzuki Y, Niimi T, Minami K, Yamamoto M, Altannamar TJ, Erkhmbaatar T, Furukawa H, Daack-Hirsch S, L' heureux J, Brandon CA, Weinberg SM, Neiswanger K, Deleyianis FW, de Salamanca JE, Vieira AR, Lidral AC, Martin JF, Murray JC
    • Journal Title

      Am J Hum Genet

      Volume: 84(3) Pages: 406-11

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Cleft Lip and/or Palate Congenital Oral Disease Gene Bank 20092009

    • Author(s)
      N. Natsume, t. Uchiyama, Y. Imai, N. Nakamura, S. Ozeki, T. Takahashi, H. Snakawa, S. Suzuki, W. Yoshida, T. Hayakawa
    • Journal Title

      Internation Transaction of Cleft and Related Craniofacial Anomalies

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Association study of folate pathway gene polymorphisms, and nonsyndromic cleft lip with/without cleft palate in a Japanese population2009

    • Author(s)
      Takahiro Goto, Keiichi Arakaki, Nagato Natsume, Hajime Sunakawa
    • Journal Title

      Ryukyu Med. J.

      Volume: 28(3, 4) Pages: 13-21

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Presentation] 口唇・口蓋裂患者に関する疫学的研究第50報-モンゴル国における調査報告-2011

    • Author(s)
      夏目長門
    • Organizer
      第35回日本口蓋裂学会総会・学術集会
    • Place of Presentation
      朱鷺メッセ新潟コンベンションセンター
    • Year and Date
      2011-05-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] Epidmiological and Charitable Project for Clep Lip/Palate care in Mongolia2011

    • Author(s)
      Nagato Natsume
    • Organizer
      Cleft 2011 International Meeting
    • Place of Presentation
      USA
    • Related Report
      2011 Final Research Report
  • [Presentation] 口唇・口蓋裂患者に関する疫学的研究第50報-モンゴル国における調査報告-2011

    • Author(s)
      夏目長門
    • Organizer
      第35回日本口蓋裂学会総会・学術集会
    • Place of Presentation
      新潟
    • Related Report
      2011 Final Research Report
  • [Presentation] Epidemiological and Charitable Project for Cleft Lip/Palate care in Mongolia2011

    • Author(s)
      Nagato Natsume
    • Organizer
      Cleft 2011 International Meeting
    • Place of Presentation
      San Francisco California, USA
    • Related Report
      2011 Annual Research Report
  • [Presentation] 口唇・口蓋裂患者に関する疫学的研究 第49報-平成22年度調査報告-2010

    • Author(s)
      夏目長門
    • Organizer
      第53回NPO法人日本口腔科学会中部地方部会
    • Place of Presentation
      富山国際会議場
    • Year and Date
      2010-10-02
    • Related Report
      2010 Annual Research Report
  • [Presentation] 口唇・口蓋裂患者に関する疫学的研究第49報-平成22年度調査-2010

    • Author(s)
      夏目長門
    • Organizer
      第53回NPO法人日本口腔科学会中部地方部会
    • Place of Presentation
      富山
    • Related Report
      2011 Final Research Report
  • [Presentation] Monitaring on Japanese cleft lip and palate patients conducted over a quarter of a century2009

    • Author(s)
      Nagato Natsume
    • Organizer
      American Cleft Palate-Craniofaial Association 66th Annual Meeting
    • Place of Presentation
      USA
    • Related Report
      2011 Final Research Report
  • [Presentation] Monitaring on Japanese cleft lip and palate patients conducted over a quarter of a century2009

    • Author(s)
      Nagato Natsume
    • Organizer
      American Cleft Palate-Craniofacial Association 66th Annual Meeting
    • Place of Presentation
      Scottsdale, Arizona USA
    • Related Report
      2009 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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