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Comprehensive and biological analysis of glycosphingolipid function expressed on cell using bioinformatics technique

Research Project

Project/Area Number 21500293
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Bioinformatics/Life informatics
Research InstitutionNational Research Institute for Child Health and Development

Principal Investigator

NAKAJIMA Hideki  独立行政法人国立成育医療研究センター, 小児血液・腫瘍研究部, 研究員 (30450620)

Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords糖鎖 / 情報工学 / マイクロアレイ / 生体分子 / 細胞 / 組織 / 細胞・組織
Research Abstract

The data processing software of liquid chromatography-mass spectrometer(LC-MS) was developed and the software was applied for the analysis of glycolipid expression in some different types of infantile leukemia cell. Each different type of leukemia cells was categorized using the software by the statistical analysis of glycosphingolipid expression. Especially, new glycosphingolipid marker, Ln3Cer could be discovered in some type of leukemia cell using the software analysis.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (8 results)

All 2011 2010 Other

All Presentation (7 results) Remarks (1 results)

  • [Presentation] LC-MS/MSによる代謝異常症の高感度検出2011

    • Author(s)
      中島英規
    • Organizer
      日本電気泳動学会シンポジウム・臨床プロテオーム研究会連合大会
    • Place of Presentation
      山口県山口大学
    • Year and Date
      2011-05-10
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] ヒト人工多能性幹(iPS)細胞における糖脂質の比較解析2011

    • Author(s)
      尾島琢磨,中島英規,梅澤明広
    • Organizer
      日本再生医療学会
    • Place of Presentation
      東京都京王プラザホテル
    • Year and Date
      2011-03-01
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] ヒト人工多能性幹(ips)細胞における糖脂質の比較解析2011

    • Author(s)
      尾島琢磨, 中島英規, 梅澤明広
    • Organizer
      日本再生医療学会
    • Place of Presentation
      東京都京王プラザホテル
    • Year and Date
      2011-03-01
    • Related Report
      2010 Annual Research Report
  • [Presentation] タンテムマス質量分析器を用いたポンペ病の診断法の開発2010

    • Author(s)
      中島英規,藤本純一郎,奥山虎之
    • Organizer
      日本先天代謝異常学会総会、アジア先天性代謝異常症シンポジウム
    • Place of Presentation
      大阪府大阪国際会議場
    • Year and Date
      2010-10-21
    • Related Report
      2011 Final Research Report
  • [Presentation] タンテムマス質量分析器を用いたポンペ病の診断法の開発2010

    • Author(s)
      中島英規, 藤本純一郎, 奥山虎之
    • Organizer
      日本先天代謝異常学会総会、アジア先天性代謝異常症シンポジウム
    • Place of Presentation
      大阪府 大阪国際会議場
    • Year and Date
      2010-10-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] 濾紙血検体を用いたライソゾーム病の欠損酵素活性測定2010

    • Author(s)
      中島英規,藤本純一郎,奥山虎之
    • Organizer
      日本マススクリーニング学会
    • Place of Presentation
      神奈川県ワークピア横浜
    • Year and Date
      2010-08-28
    • Related Report
      2011 Final Research Report
  • [Presentation] 濾紙血検体を用いたライソゾーム病の欠損酵素活性測定2010

    • Author(s)
      中島英規, 藤本純一郎, 奥山虎之
    • Organizer
      日本マス・スクリーニング学会
    • Place of Presentation
      神奈川県ワークピア横浜
    • Year and Date
      2010-08-28
    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://www.reifycs.com/japanese/SPMSoutline_jp.html

    • Related Report
      2011 Final Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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