Development of innovative multimodal imaging probes using organosilica particle technology
| Project/Area Number |
21500409
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | The University of Tokushima |
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Principal Investigator |
NAKAMURA Michihiro 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 准教授 (10314858)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | イメージング / ナノ粒子 / 蛍光 / 有機シリカ / マルチモダリティー / バイオイメージング / 磁性体 / MRI / X線CT / 近赤外線 / マルチモーダルイメージング |
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| Research Abstract |
In this study, we developed novel imaging probes using organosilica particle technology. We prepared various kinds of imaging probes, and they were useful for in vitro and in vivo fluorescent imaging, X-ray computed tomography(CT), magnetic resonance imaging(MRI) and so on. Furthermore we also developed multimodal imaging probes for imaging that combine fluorescent imaging, X-ray CT, and MRI. The imaging probes were useful for various applications such as in vivo detections of tumor tissue of mouse. Useful innovative multimodal imaging probes for biomedical studies were developed successfully.
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Report
(4 results)
Research Products
(76 results)
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[Journal Article] Size-Controlled Synthesis, Surface Functionalization, and Biological Applications of Thiol-Organosilica Particles.2010
Author(s)
Nakamura, M., Ozaki, S., Abe, M., Doi, H., Matsumoto, T., Ishimura, K.
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Journal Title
Colloids and Surfaces B : Biointerfaces
Volume: 79
Pages: 19-26
Related Report
Peer Reviewed
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