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Development of innovative multimodal imaging probes using organosilica particle technology

Research Project

Project/Area Number 21500409
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Biomedical engineering/Biological material science
Research InstitutionThe University of Tokushima

Principal Investigator

NAKAMURA Michihiro  徳島大学, 大学院・ヘルスバイオサイエンス研究部, 准教授 (10314858)

Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywordsイメージング / ナノ粒子 / 蛍光 / 有機シリカ / マルチモダリティー / バイオイメージング / 磁性体 / MRI / X線CT / 近赤外線 / マルチモーダルイメージング
Research Abstract

In this study, we developed novel imaging probes using organosilica particle technology. We prepared various kinds of imaging probes, and they were useful for in vitro and in vivo fluorescent imaging, X-ray computed tomography(CT), magnetic resonance imaging(MRI) and so on. Furthermore we also developed multimodal imaging probes for imaging that combine fluorescent imaging, X-ray CT, and MRI. The imaging probes were useful for various applications such as in vivo detections of tumor tissue of mouse. Useful innovative multimodal imaging probes for biomedical studies were developed successfully.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (76 results)

All 2012 2011 2010 2009 Other

All Journal Article (20 results) (of which Peer Reviewed: 20 results) Presentation (43 results) Book (2 results) Remarks (6 results) Patent(Industrial Property Rights) (5 results) (of which Overseas: 3 results)

  • [Journal Article] Time-lapse fluorescence imaging and quantitative single cell and endosomal analysis of peritoneal macrophages using fluorescent organosilica nanoparticles2012

    • Author(s)
      Nakamura M, Miyamoto K, Hayashi K, Awaad A, Ochiai M, Ishimura K
    • Journal Title

      Nanomedicine : NBM

      Volume: (in press)

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Near-Infrared Fluorescent Silica/ Porphyrin Hybrid Nanorings for In Vivo Cancer Imaging2012

    • Author(s)
      Hayashi K, Nakamura M, Miki H, Ozaki S, Abe M, Matsumoto T, Ishimura K
    • Journal Title

      Advanced Functional Materials

      Volume: (in press) Issue: 17 Pages: 3539-3546

    • DOI

      10.1002/adfm.201200219

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Imaging of size dependent uptake and identification of novel pathway in mouse Peyer' s patches using fluorescent organosilica particles2012

    • Author(s)
      Awaad A, Nakamura M, Ishimura. K
    • Journal Title

      Nanomedicine : NBM

      Volume: (in press) Issue: 5 Pages: 627-636

    • DOI

      10.1016/j.nano.2011.08.009

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Histochemical and biochemical analysis of the size-dependent nano-immunoresponse in mouse Peyer' s patches using fluorescent organosilica particles2012

    • Author(s)
      Awaad A, Nakamura M, Ishimura K
    • Journal Title

      International Journal of Nanomedicine

      Volume: 7 Pages: 1423-1439

    • DOI

      10.2147/ijn.s28675

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] One-pot synthesis and characterization of dual fluorescent thiol-organosilica nanoparticles as non-photoblinking quantum dots and their applications for biological imaging2011

    • Author(s)
      Nakamura M, Ozaki S, Abe M, Matsumoto T, Ishimura K
    • Journal Title

      Journal of Materials Chemistry

      Volume: 21 Issue: 12 Pages: 4689-4695

    • DOI

      10.1039/c0jm04259e

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] In situ synthesis and photoresponsive rupture of organosilica nanocapsules2011

    • Author(s)
      Hayashi K, Nakamura M, Ishimura K
    • Journal Title

      Chemical Communications

      Volume: 47 Issue: 32 Pages: 1518-1520

    • DOI

      10.1039/c2cc17444h

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Formation of sea urchin-like hierarchical nanostructures of tio2 by enzyme-mediated self-assembly for destruction of macrophages2011

    • Author(s)
      Hayashi K, Nakamura M, Sakamoto W, Yogo T, Kori T, Ishimura K
    • Journal Title

      Chemistry of Materials

      Volume: 23 Issue: 14 Pages: 3341-3347

    • DOI

      10.1021/cm200826c

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Synthesis and photocatalytic activity of sea urchin-shaped rutile TiO2 nanocrystals2011

    • Author(s)
      Hayashi K, Nakamura M, Makita Y, Fujiwara R, Kori T, Ishimura K
    • Journal Title

      Materials Letters

      Volume: 65 Issue: 19-20 Pages: 3037-3040

    • DOI

      10.1016/j.matlet.2011.06.044

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] In Situ Synthesis and Photoresponsive Rupture of Organosilica Nanocapsules.2011

    • Author(s)
      Hayashi, H., Nakamura, M., Ishimura, K.
    • Journal Title

      Chemical Communications

      Volume: 47 Pages: 1518-1520

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] One-Pot Synthesis And Characterization of Dual Fluorescent Thiol-Organosilica Nanoparticles As Non-Photoblinking Quantum Dots and Their Applications for Biological Imaging.2011

    • Author(s)
      Nakamura, M., Ozaki, S., Abe, M., Matsumoto, T., Ishimura, K.
    • Journal Title

      Journal of Materials Chemistry

      Volume: 21 Pages: 4689-4695

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Size-controlled synthesis, surface functionalization, and biological applications of thiol-organosilica particles2010

    • Author(s)
      Nakamura M, Ozaki S, Abe M, Doi H, Matsumoto T, Ishimura K
    • Journal Title

      Colloids and Surfaces B : Biointerfaces

      Volume: 79 Issue: 1 Pages: 19-26

    • DOI

      10.1016/j.colsurfb.2010.03.008

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Rapid size evaluation of nanoparticles using flow cytometry2010

    • Author(s)
      Nakamura M, Ishimura K
    • Journal Title

      Advanced Science Letters

      Volume: 3(2) Issue: 2 Pages: 130-137

    • DOI

      10.1166/asl.2010.1096

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Control of emission peaks of x-ray phosphor using dye-silica nanoparticles2010

    • Author(s)
      Miyoshi H, Imura H, Nakamura M
    • Journal Title

      Journal of luminescence

      Volume: 130 Issue: 3 Pages: 404-410

    • DOI

      10.1016/j.jlumin.2009.10.004

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] 新規な有機シリカナノ粒子の作製と光線力学的治療への応用2010

    • Author(s)
      中村教泰、石村和敬
    • Journal Title

      日本レーザー医学会誌

      Volume: 30(4) Pages: 394-398

    • NAID

      10026089039

    • Related Report
      2011 Final Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Size-Controlled Synthesis, Surface Functionalization, and Biological Applications of Thiol-Organosilica Particles.2010

    • Author(s)
      Nakamura, M., Ozaki, S., Abe, M., Doi, H., Matsumoto, T., Ishimura, K.
    • Journal Title

      Colloids and Surfaces B : Biointerfaces

      Volume: 79 Pages: 19-26

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Rapid Size Evaluation of Nanoparticles using Flow Cytometry.2010

    • Author(s)
      Nakamura, M., Ishimura, K.
    • Journal Title

      Advanced Science Letters

      Volume: 3 Pages: 130-137

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Control of Emission Peaks of X-ray Phosphor Using Dye-Silica Nanoparticles2010

    • Author(s)
      Hirokazu Miyoshi, Hiroyoshi Imura, Michihiro Nakamura
    • Journal Title

      Journal of Luminescence 130

      Pages: 404-410

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 新規な有機シリカナノ粒子の作製と光線力学的治療への応用2010

    • Author(s)
      中村教泰、石村和敬
    • Journal Title

      日本レーザー医学会誌 30

      Pages: 394-398

    • NAID

      10026089039

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Rapid Size Evaluation of Nanoparticles using Flow Cytometry2010

    • Author(s)
      Michihiro Nakamura, Kazunori Ishimura
    • Journal Title

      Advanced Science Letters 3

      Pages: 130-137

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Size-Controlled Synthesis, Surface Functionalization, and Biological Applications of Thiol-Organosilica Particles2010

    • Author(s)
      Michihiro Nakamura, et al.
    • Journal Title

      Colloids and Surfaces B : Biointerfaces (in press)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] Quantitative single cell analysis of macrophages using fluorescent organosilica nanoparticles surface-modified with polyethylene glycol2011

    • Author(s)
      Kanadani T
    • Organizer
      The 11th US-Japan Symposium on Drug Delivery Systems Conference
    • Place of Presentation
      Hawaii, USA
    • Year and Date
      2011-12-20
    • Related Report
      2011 Final Research Report
  • [Presentation] Preparation of novel multifunctionalized nanoparticles for multimodal DDI using organosilica particles technology2011

    • Author(s)
      Nakamura M
    • Organizer
      The 11th US-Japan Symposium on Drug Delivery Systems Conference
    • Place of Presentation
      Hawaii, USA
    • Year and Date
      2011-12-20
    • Related Report
      2011 Final Research Report
  • [Presentation] Imaging of size dependent uptake and identification of novel pathway in mouse Peyer's patches using fluorescent organosilica particles2011

    • Author(s)
      Awaad A, et al
    • Organizer
      The 11th US-Japan Symposium on Drug Delivery Systems Conference
    • Place of Presentation
      The Westin Maui, Lahaina, Hawaii, USA
    • Year and Date
      2011-12-20
    • Related Report
      2011 Annual Research Report
  • [Presentation] Preparation of Novel Muitifunctionalized Nanoparticies for Multimodal DDI using Organosilica Particles Technology2011

    • Author(s)
      Nakamura M, et al
    • Organizer
      The 11th US-Japan Symposium on Drug Delivery Systems Conference
    • Place of Presentation
      The Westin Maui, Lahaina, Hawaii, USA
    • Year and Date
      2011-12-20
    • Related Report
      2011 Annual Research Report
  • [Presentation] Quantitative Single Cell Analysis of Macrophages using Fluorescent Organosilica Nanoparticles Surface-modified with Polyethylene Glycol2011

    • Author(s)
      Kanadani T, et al.
    • Organizer
      The 11th US-Japan Symposium on Drug Delivery Systems Conference
    • Place of Presentation
      The Westin Maui, Lahaina, Hawaii, USA
    • Year and Date
      2011-12-20
    • Related Report
      2011 Annual Research Report
  • [Presentation] Imaging of size dependent uptake and identification of novel pathway in mouse Peyer' s patches using fluorescent organosilica particles2011

    • Author(s)
      Awaad A
    • Organizer
      The 11th US-Japan Symposium on Drug Delivery Systems Conference
    • Place of Presentation
      Hawaii, USA
    • Year and Date
      2011-12-18
    • Related Report
      2011 Final Research Report
  • [Presentation] 酸化鉄粒子を用いた新規MRI用プローブ開発における緩和時間特性の評価2011

    • Author(s)
      太田傑
    • Organizer
      平成23年度中四国放射線医療技術フォーラム
    • Place of Presentation
      米子コンベンションセンター(米子市)
    • Year and Date
      2011-11-27
    • Related Report
      2011 Final Research Report
  • [Presentation] 酸化鉄粒子を用いた新規MRI用プローブ開発における緩和時間特性の評価2011

    • Author(s)
      太田傑
    • Organizer
      平成23年度中四国放射線医療技術フォーラム
    • Place of Presentation
      米子コンベンションセンター(鳥取県米子市)
    • Year and Date
      2011-11-27
    • Related Report
      2011 Annual Research Report
  • [Presentation] 新規な有機シリカ・マルチモーダル分子イメージング用ナノ粒子2011

    • Author(s)
      中村教泰
    • Organizer
      JSTイノベーションサテライト徳島・研究成果報告会
    • Place of Presentation
      ホテルクレメント徳島(徳島市)
    • Year and Date
      2011-10-28
    • Related Report
      2011 Final Research Report
  • [Presentation] 新規な有機シリカ・マルチモーダル分子イメージング用ナノ粒子2011

    • Author(s)
      中村教泰
    • Organizer
      JSTイノベーションサテライト徳島・研究成果報告会
    • Place of Presentation
      ホテルクレメント徳島(徳島市)(招待講演)
    • Year and Date
      2011-10-28
    • Related Report
      2011 Annual Research Report
  • [Presentation] 新規なマルチモーダル分子イメージング用ナノ粒子2011

    • Author(s)
      中村教泰
    • Organizer
      イノベーション・ジャパン2011-大学見本市・「新技術説明会」
    • Place of Presentation
      東京国際フォーラム(有楽町)
    • Year and Date
      2011-09-22
    • Related Report
      2011 Final Research Report
  • [Presentation] 新規なマルチモーダル分子イメージング用ナノ粒子2011

    • Author(s)
      中村教泰
    • Organizer
      イノベーション・ジャパン2011-大学見本市・技術説明会
    • Place of Presentation
      東京国際フォーラム(有楽町)
    • Year and Date
      2011-09-22
    • Related Report
      2011 Annual Research Report
  • [Presentation] 有機シリカ粒子技術を用いたnon-photoblinking量子ドットの作製とユニバーサル多重蛍光イメージング2011

    • Author(s)
      中村教泰
    • Organizer
      第6回日本分子イメージング学会総会・学術集会
    • Place of Presentation
      神戸国際会議場(神戸市
    • Year and Date
      2011-05-27
    • Related Report
      2011 Final Research Report
  • [Presentation] 有機シリカ粒子技術を用いたnon-photoblinking量子ドットの作製とユニパーサル多重蛍光イメージング2011

    • Author(s)
      中村教泰
    • Organizer
      第6回日本分子イメージング学会総会・学術集会
    • Place of Presentation
      神戸国際会議場(兵庫県)
    • Year and Date
      2011-05-27
    • Related Report
      2011 Annual Research Report
  • [Presentation] 解剖学・生理学モデル講義「組織学総論・血液」2011

    • Author(s)
      中村教泰
    • Organizer
      第116回日本解剖学会総会・全国学術集会合同大会
    • Place of Presentation
      パシフィコ横浜会議センター(横浜市)
    • Year and Date
      2011-03-30
    • Related Report
      2011 Final Research Report
  • [Presentation] Histological analysis and multimodal imaging using multifunctionalized organosilica nanoparticles2011

    • Author(s)
      Nakamura M
    • Organizer
      第116回日本解剖学会総会・全国学術集会合同大会
    • Place of Presentation
      パシフィコ横浜会議センター(横浜市)
    • Year and Date
      2011-03-30
    • Related Report
      2011 Final Research Report
  • [Presentation] Histological analysis and multimodal imaging using multifunctionalized organosilica nanoparticles2011

    • Author(s)
      Nakamura, M, Hayashi, K., Ishimura, K.
    • Organizer
      第116回日本解剖学会総会・全国学術集会 合同大会
    • Place of Presentation
      パシフィコ横浜会議センター
    • Year and Date
      2011-03-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] 解剖学・生理学モデル講義「組織学総論・血液」2011

    • Author(s)
      中村教泰
    • Organizer
      第116回日本解剖学会総会・全国学術集会 合同大会
    • Place of Presentation
      パシフィコ横浜会議センター
    • Year and Date
      2011-03-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] 光線力学療法のためのウニ状酸化チタンナノ構造体の合成2011

    • Author(s)
      林幸壱朗
    • Organizer
      日本セラミックス協会年会
    • Place of Presentation
      静岡大学浜松キャンパス(浜松市)
    • Year and Date
      2011-03-17
    • Related Report
      2011 Final Research Report
  • [Presentation] 光線力学療法のためのウニ状酸化チタンナノ構造体の合成2011

    • Author(s)
      Hayashi, K., Nakamura, M., Ishimura, K.
    • Organizer
      日本セラミックス協会 2011年年会
    • Place of Presentation
      静岡大学浜松キャンパス
    • Year and Date
      2011-03-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] シリカをコーティングした酸化亜鉛微粒子の発光特性2011

    • Author(s)
      橋本英樹
    • Organizer
      第9回医用分光学研究会
    • Place of Presentation
      島根大学生物資源科学部1号館(松江市)
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 新規なマルチモーダル分子イメージング用ナノ粒子2011

    • Author(s)
      中村教泰
    • Organizer
      イノベーション・ジャパン2011-大学見本市・展示会
    • Place of Presentation
      東京国際フォーラム(有楽町)
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] シリカをコーティングした酸化亜鉛微粒子の作製2011

    • Author(s)
      橋本英樹
    • Organizer
      ナノ学会第9回大会
    • Place of Presentation
      北海道大学・学術交流会館(札幌市)
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] Preparation of novel multifunctionalized hybrid nanoparticles using organosilica particles technology2010

    • Author(s)
      Nakamura M
    • Organizer
      3rd International Congress on Ceramics
    • Place of Presentation
      Osaka International Convention Center(大阪市)
    • Year and Date
      2010-11-16
    • Related Report
      2011 Final Research Report
  • [Presentation] Preparation of Novel Multifunctionalized Hybrid Nanoparticles using Organosilica Particles Technology.2010

    • Author(s)
      Nakamura, M., Hayashi, K., Ishimura, K.
    • Organizer
      3^<rd> International Congress on Ceramics
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2010-11-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] In-situ template-free synthesis of organosilica nanocapsules2010

    • Author(s)
      Hayashi K
    • Organizer
      3rd International Congress on Ceramics
    • Place of Presentation
      Osaka International Convention Center(大阪市)
    • Year and Date
      2010-11-15
    • Related Report
      2011 Final Research Report
  • [Presentation] In-Situ, Template-Free Synthesis of Organosilica Nanocapsules.2010

    • Author(s)
      Hayashi, K., Nakamura, M., Ishimura, K.
    • Organizer
      3^<rd> International Congress on Ceramics
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2010-11-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] Preparation of novel multimodal imaging nanoparticles using organosilica particles technology2010

    • Author(s)
      Nakamura M
    • Organizer
      2010 World Molecular Imaging Congress
    • Place of Presentation
      Kyoto International Conference Center(京都市)
    • Year and Date
      2010-09-08
    • Related Report
      2011 Final Research Report
  • [Presentation] Preparation of Novel Multimodal Imaging Nanoparticles using Organosilica Particles Technology2010

    • Author(s)
      Nakamura, M., Ishimura, K.
    • Organizer
      2010 World Molecular Imaging Congress
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2010-09-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] 有機シリカ粒子技術による多機能ナノ粒子の作製とマルチモーダルDDI2010

    • Author(s)
      中村教泰
    • Organizer
      第26回日本DDS学会
    • Place of Presentation
      大阪国際交流センター(大阪市)
    • Year and Date
      2010-06-18
    • Related Report
      2011 Final Research Report
  • [Presentation] 有機シリカ粒子技術による多機能ナノ粒子の作製とマルチモーダルDDI2010

    • Author(s)
      中村教泰, 石村和敬
    • Organizer
      第26回日本DDS学会
    • Place of Presentation
      大阪国際交流センター
    • Year and Date
      2010-06-18
    • Related Report
      2010 Annual Research Report
  • [Presentation] 有機シリカ粒子技術による新規なマルチモーダルイメージングナノ粒子の作製2010

    • Author(s)
      中村教泰
    • Organizer
      日本分子イメージング学会第5回学会総会・学術集会
    • Place of Presentation
      ピアザ淡海(滋賀県大津市)
    • Year and Date
      2010-05-22
    • Related Report
      2011 Final Research Report
  • [Presentation] 有機シリカ粒子技術による新規なマルチモーダルイメージングナノ粒子の作製2010

    • Author(s)
      中村教泰、石村和敬
    • Organizer
      日本分子イメージング学会第5回学会総会・学術集会
    • Place of Presentation
      ピアザ淡海
    • Year and Date
      2010-05-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] Organosilica particles technology as a novel surface processing for magnet particles2010

    • Author(s)
      Nakamura M
    • Organizer
      11th Joint MMM/ Intermag Conference
    • Place of Presentation
      Marriott Washington Wardman Park,(DC, US)
    • Year and Date
      2010-01-22
    • Related Report
      2011 Final Research Report
  • [Presentation] Organosilica particles technology as a novel surface processing for magnet particles2010

    • Author(s)
      Michihiro Nakamura, Kazunori Ishimura
    • Organizer
      11th Joint MMM/Intermag Conference
    • Place of Presentation
      Marriott Washington Wardman Park, DC, US
    • Year and Date
      2010-01-22
    • Related Report
      2009 Annual Research Report
  • [Presentation] 有機シリカ粒子技術を用いた新規なマルチモーダルイメジングプローブの開発2009

    • Author(s)
      中村教泰
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      アスティとくしま(徳島市)
    • Year and Date
      2009-10-31
    • Related Report
      2011 Final Research Report
  • [Presentation] 有機シリカ粒子技術を用いた新規なマルチモーダルイメージングプローブの開発2009

    • Author(s)
      中村教泰、石村和敬
    • Organizer
      第13回日本がん分子標的治療学会学術集会
    • Place of Presentation
      アスティとくしま
    • Year and Date
      2009-10-31
    • Related Report
      2009 Annual Research Report
  • [Presentation] 有機シリカ粒子技術を用いた新規なハイブリット多機能ナノ粒子の作製2009

    • Author(s)
      中村教泰
    • Organizer
      日本セラミックス協会第22回秋季シンポジウム
    • Place of Presentation
      愛媛大学城北地区(松山市)
    • Year and Date
      2009-09-16
    • Related Report
      2011 Final Research Report
  • [Presentation] 有機シリカ粒子技術を用いた新規なハイブリット多機能ナノ粒子の作製2009

    • Author(s)
      中村教泰、石村和敬
    • Organizer
      日本セラミックス協会 第22回秋季シンポジウム
    • Place of Presentation
      愛媛大学城北地区
    • Year and Date
      2009-09-16
    • Related Report
      2009 Annual Research Report
  • [Presentation] 磁性粒子の新たな表面加工技術としての有機シリカ粒子技術2009

    • Author(s)
      中村教泰
    • Organizer
      第33回日本磁気学会学術講演会
    • Place of Presentation
      長崎大学文教キャンパス(長崎市)
    • Year and Date
      2009-09-12
    • Related Report
      2011 Final Research Report
  • [Presentation] 磁性粒子の新たな表面加工技術としての有機シリカ粒子技術2009

    • Author(s)
      中村教泰、石村和敬
    • Organizer
      第33回日本磁気学会学術講演会
    • Place of Presentation
      長崎大学文教キャンパス
    • Year and Date
      2009-09-12
    • Related Report
      2009 Annual Research Report
  • [Presentation] マルチモーダル標的分子を検出する多機能有機シリカナノ粒子の創製2009

    • Author(s)
      中村教泰
    • Organizer
      第13回日本がん分子標的治療学会学術集会
    • Place of Presentation
      ホテルクレメント徳島(徳島市)
    • Year and Date
      2009-06-26
    • Related Report
      2011 Final Research Report
  • [Presentation] マルチモーダルに標的分子を検出する多機能有機シリカナノ粒子の創製2009

    • Author(s)
      中村教泰
    • Organizer
      第13回日本かん分子標的治療学会学術集会
    • Place of Presentation
      ホテルクレメント徳島
    • Year and Date
      2009-06-26
    • Related Report
      2009 Annual Research Report
  • [Book] Approaches to biofunctionalization of spherical silica nanomaterials, in Nanomaterials for the Life Sciencesnanomaterials2009

    • Author(s)
      Nakamura M
    • Publisher
      Nonmagnetic Inorganic Nanomaterials
    • Related Report
      2011 Final Research Report
  • [Book] Approaches to Biofunctionalization of Spherical Silica Nanomaterials. In : Kumar C.S.S.R., editior. Nanomaterial for Life Sciences Volume 2 : Nanostructured Oxides.2009

    • Author(s)
      Michihiro Nakamura
    • Total Pages
      53
    • Publisher
      Wiley-VCH Verlag GmbH & Co.KGaA
    • Related Report
      2009 Annual Research Report
  • [Remarks] ホームページ等・所属機関ホームページ

    • URL

      http://www.tokushima-u.ac.jp/med/culture/kenbikaibou/

    • Related Report
      2011 Final Research Report
  • [Remarks] ホームページ等・研究紹介ホームページ

    • URL

      http://organosilica.com

    • Related Report
      2011 Final Research Report
  • [Remarks]

    • URL

      http://www.tokushima-u.ac.jp/med/culture/kenbikaibou/

    • Related Report
      2011 Annual Research Report
  • [Remarks]

    • URL

      http://organosilica.com/

    • Related Report
      2011 Annual Research Report
  • [Remarks] 研究者個人

    • URL

      http://organosilica.com/

    • Related Report
      2010 Annual Research Report
  • [Remarks] 所属研究機関

    • URL

      http://www.med.tokushima-u.ac.jp/article/0015536.html

    • Related Report
      2010 Annual Research Report
  • [Patent(Industrial Property Rights)] フローサイトメトリーによる細胞の検出・分取システム、及び検出・分取方法2011

    • Inventor(s)
      會澤英樹、大久保典雄、中村教泰、三好弘一
    • Industrial Property Rights Holder
      徳島大学、古河電工株式会社
    • Acquisition Date
      2011-04-08
    • Related Report
      2011 Final Research Report
    • Overseas
  • [Patent(Industrial Property Rights)] フローサイトメトリーによる生体分子の定量システム、及び定量方法2011

    • Inventor(s)
      會澤英樹、大久保典雄、中村教泰、三好弘一
    • Industrial Property Rights Holder
      徳島大学、古河電工株式会社
    • Acquisition Date
      2011-05-27
    • Related Report
      2011 Final Research Report
  • [Patent(Industrial Property Rights)] 標的生体分子標識用もしくは標的細胞標識用の蛍光シリカ粒子組成物、及びこれを用いたフローサイトメトリー用マルチプレックシングキット2010

    • Inventor(s)
      會澤英樹、大久保典雄、中村教泰、三好弘一
    • Industrial Property Rights Holder
      徳島大学、古河電工株式会社
    • Acquisition Date
      2010-11-04
    • Related Report
      2011 Final Research Report
  • [Patent(Industrial Property Rights)] NANOFUNCTIONAL SILICA PARTICLES AND MANUFACTURING METHOD THEREOF2009

    • Inventor(s)
      中村教泰
    • Industrial Property Rights Holder
      徳島大学
    • Filing Date
      2009-06-11
    • Related Report
      2011 Final Research Report
    • Overseas
  • [Patent(Industrial Property Rights)] NANOFUNCTIONAL SILICA PARTICLES AND MANUFACTURING METHOD THEREOF2009

    • Inventor(s)
      Michihiro Nakamura
    • Industrial Property Rights Holder
      徳島大学
    • Filing Date
      2009-11-06
    • Related Report
      2009 Annual Research Report
    • Overseas

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Published: 2009-04-01   Modified: 2016-04-21  

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