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Temperature receptors in treatment of neurogenic bladder

Research Project

Project/Area Number 21500479
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionKagoshima University

Principal Investigator

YOSHIDA Akira  鹿児島大学, 医歯学総合研究科, 助教 (40347109)

Co-Investigator(Kenkyū-buntansha) IKEDA Satoshi  鹿児島大学, 医学部・歯学部附属病院, 講師 (00343369)
OOWATASHI Akihiko  鹿児島大学, 医学部, 助教 (30295282)
KAWAHIRA Kazumi  鹿児島大学, 大学院・医歯学総合研究科, 教授 (20117493)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords温熱 / ラズベリーケトン / ラット / シストメトリー / シスメトリー / 温度受容体 / 排尿筋
Research Abstract

We investigated the effect of warming on detrusor smooth muscle contraction and the effect of warming and intravesical infusion of raspberry ketone on micturition reflex in rats. Warming inhibited high K and carbachol-induced contractions and reduced resting tension and amplitude of spontaneous contraction. Inhibition of carbachol. induced contraction was due to the inhibition of intracellular calcium mobilization. Warming tended to reduce pressure threshold for inducing micturition, micturition pressure and basal pressure. Intravesical infusion of raspberry ketone had no effect on micturition reflex.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (9 results)

All 2011 2010 2009

All Journal Article (2 results) Presentation (5 results) Book (2 results)

  • [Journal Article] 排尿障害に関する基礎研究2011

    • Author(s)
      吉田輝
    • Journal Title

      Japanese Journal of Rehabilitation Medicine

      Volume: 48巻 Pages: 259-262

    • Related Report
      2011 Final Research Report
  • [Journal Article] 排尿障害に関する基礎研究2011

    • Author(s)
      吉田輝
    • Journal Title

      Jpn J Rehabil Med

      Volume: 48巻 Pages: 259-262

    • Related Report
      2010 Annual Research Report
  • [Presentation] ラット排尿筋収縮に対する温熱の影響の検討2011

    • Author(s)
      吉田輝、野元佳子、池田聡、根路銘周子、上川百合恵、原田雄大、川平和美
    • Organizer
      第48回日本リハビリテーション医学会学術集会
    • Place of Presentation
      幕張メッセ(千葉市)
    • Year and Date
      2011-11-02
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 排尿障害に関する基礎研究2010

    • Author(s)
      吉田輝
    • Organizer
      第47回日本リハビリテーション医学会学術集会
    • Place of Presentation
      みなみホール(鹿児島市)
    • Year and Date
      2010-05-21
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] Effect of raspberry ketone on detrusor smooth muscle contraction in rats2010

    • Author(s)
      Akira Yoshida、Yurika Shimozono、Akihiko Ohwatashi、Satoshi Ikeda、Yurie Kamikawa、Kazumi Kawahira
    • Organizer
      Joint Annual Meeting of International Continence Society & International Urogynecological Association
    • Place of Presentation
      Toronto、Canada
    • Related Report
      2011 Final Research Report
  • [Presentation] 温熱がラット排尿筋収縮へ及ぼす影響の検討2009

    • Author(s)
      吉田輝、大渡昭彦、下園由理香、池田聡、上川百合恵、原田雄大、根路銘周子、川平和美
    • Organizer
      第16回日本排尿機能学会
    • Place of Presentation
      JALリゾートシーホークホテル福岡(福岡市)
    • Year and Date
      2009-09-11
    • Related Report
      2011 Final Research Report
  • [Presentation] 温熱がラット排尿筋収縮へ及ぼす影響の検討2009

    • Author(s)
      吉田輝
    • Organizer
      第16回 日本排尿機能学会
    • Place of Presentation
      JALリゾート シーホークホテル福岡
    • Year and Date
      2009-09-11
    • Related Report
      2009 Annual Research Report
  • [Book] 脊髄損傷における排尿障害の診療ガイドライン2011

    • Author(s)
      井川靖彦、小川隆敏、柿崎秀宏、木元康介、関戸哲利、仙石淳、田中克幸、田中博、永松秀樹、浪間孝重、百瀬均、森田肇、大濱眞、木下幸子、幸田剣、吉田輝、吉田雅博、松尾清美
    • Total Pages
      112
    • Publisher
      リッチヒルメディカル
    • Related Report
      2011 Final Research Report
  • [Book] 脊髄損傷における排尿障害の診療ガイドライン2011

    • Author(s)
      日本排尿機能学会/日本脊髄障害医学会
    • Total Pages
      112
    • Publisher
      リッチヒルメディカル
    • Related Report
      2011 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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