Temperature receptors in treatment of neurogenic bladder
| Project/Area Number |
21500479
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Kagoshima University |
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Principal Investigator |
YOSHIDA Akira 鹿児島大学, 医歯学総合研究科, 助教 (40347109)
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| Co-Investigator(Kenkyū-buntansha) |
IKEDA Satoshi 鹿児島大学, 医学部・歯学部附属病院, 講師 (00343369)
OOWATASHI Akihiko 鹿児島大学, 医学部, 助教 (30295282)
KAWAHIRA Kazumi 鹿児島大学, 大学院・医歯学総合研究科, 教授 (20117493)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | 温熱 / ラズベリーケトン / ラット / シストメトリー / シスメトリー / 温度受容体 / 排尿筋 |
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| Research Abstract |
We investigated the effect of warming on detrusor smooth muscle contraction and the effect of warming and intravesical infusion of raspberry ketone on micturition reflex in rats. Warming inhibited high K and carbachol-induced contractions and reduced resting tension and amplitude of spontaneous contraction. Inhibition of carbachol. induced contraction was due to the inhibition of intracellular calcium mobilization. Warming tended to reduce pressure threshold for inducing micturition, micturition pressure and basal pressure. Intravesical infusion of raspberry ketone had no effect on micturition reflex.
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Report
(4 results)
Research Products
(9 results)
