| Project/Area Number |
21500663
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied health science
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| Research Institution | Nippon Medical School |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KAWADA Tomoyuki 日本医科大学, 医学(系)研究科(研究院), 教授 (00224791)
INAGAKI Hirofumi 日本医科大学, 医学部, 講師 (50213111)
HIRATA Yukiyo 日本医科大学, 医学部, 助教 (40322515)
HIRATA Kimiko 日本医科大学, 医学(系)研究科(研究院), その他 (70445815)
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| Project Period (FY) |
2009 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 受動喫煙 / ストレス評価 / 唾液 / カテコールアミン代謝物 / HPLC 分析 / コルチゾール / HPLC定量分析 / 受動喫堙 |
|---|
| Research Abstract |
The purpose of this study was to perform stress evaluation of the second hand smoke (SHS) exposure by salivary catecholamine metabolites. SHS exposure was surveyed by a questionnaire, and salivary cotinine level was measured for the nonsmokers. Then, the subjects were loaded with Uchida-Kraepelin test, and salivary cortisol and 3-Methoxy-4-hydroxyphenylglycol (MHPG) of catecholamine metabolite level was measured. Salivary MHPG level of a subject exposed to second hand smoke was significantly high after Uchida-Kraepelin test. Therefore, the salivary MHPG level was suggested to be valuable as a stress evaluation of second hand smoke exposure.
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