Micro-Scale Sample Preparation Devices for Novel Non-Invasive Screening Diagnosis with Human Breath Samples
| Project/Area Number |
21550078
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Analytical chemistry
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| Research Institution | Toyohashi University of Technology |
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Principal Investigator |
SAITO Yoshihiro 豊橋技術科学大学, 大学院・工学研究科, 准教授 (00303701)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 試料処理 / 呼気診断 / 非侵襲診断 / マイクロ化 / 針型デバイス / 糖尿病 / 抽出 / 試料前処理 / 呼気分析 / マイクロ抽出法 / 高感度検出 / ガスクロマトグラフィー / 非侵襲診断技術 / 空気環境測定 |
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| Research Abstract |
In this work, a novel non-invasive diagnosis technique with human breath sample was developed for the screening of diabetic patients. The developed needle-type sample preparation method has several advantageous features such as an excellent storage performance and easy operations during the sampling process. The correlation between the acetone concentration in breath samples and the total concentrations of ketone bodies was confirmed along with a good correlation between the acetone concentration and the HbA1c% in blood, suggesting a successful development of this technique as a quick screening technique.
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Report
(4 results)
Research Products
(32 results)
