Development of Fluorescent Probes for the Detection of Various Angiogenesis Factors and Their Application to Medical Diagnostics
| Project/Area Number |
21560814
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Biofunction/Bioprocess
|
|---|
| Research Institution | National Institute of Advanced Industrial Science and Technology |
|---|
Principal Investigator |
SUZUKI Yoshio 独立行政法人産業技術総合研究所, バイオメディカル研究部門, 主任研究員 (60321907)
|
|---|
| Project Period (FY) |
2009 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
|---|
| Keywords | バイオセンサー / 血管内皮細胞増殖因子 / 蛍光 / タンパク質 / センサー / 分子プローブ / 色素 |
|---|
| Research Abstract |
Design and synthesis of fluorescent probes for the detection of angiogenesis was carried out based on the knowledge obtained by the development of fluorescent reagents for the detection of proteins. As a result, molecular probes for the detection of VEGF constructed by peptides and fluorescent molecules were developed, and the highly sensitive and easy detection of VEGF was successful with the use of nano-pillar substrates.
|
Report
(4 results)
Research Products
(37 results)
