Silencing mechanisms of plant heterochromatin regions
| Project/Area Number |
21570008
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Genetics/Genome dynamics
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| Research Institution | National Institute of Agrobiological Sciences |
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Principal Investigator |
HABU Yoshiki 独立行政法人農業生物資源研究所, ゲノム機能改変研究ユニット, 主任研究員 (80266915)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | サイレンシング / 反復配列 / シトシンメチル化 / シロイヌナズナ / MORPHEUS' MOLECULE1 / エピジェネティクス / DNAメチル化 / ヒストンメチル化 / Morpheus' Molecule 1 / トランスポゾン / 小分子RNA / Morpheus'Molecule 1 |
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| Research Abstract |
We analyzed function of factors involved in silencing of endogenous repetitive elements in the plant genome. The results suggested the presence of three independent silencing pathways regulated by(1) MORPHEUS' MOLECULE1(MOM1),(2) RNA-directed DNA methylation(RdDM), and(3) both of MOM1 and RdDM, respectively. Chromodomain is often found in MOM1 protein of plants other than Arabidopsis thaliana, but our analysis indicated that it is dispensable for silencing activity of MOM1.
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Report
(4 results)
Research Products
(24 results)
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[Journal Article] Transduction of RNA-directed DNA methylation signals to repressive histone marks in Arabidopsis thaliana2010
Author(s)
Numa H, Kim J-M, Matsui A, Kurihara Y, Morosawa T, Ishida J, Mochizuki Y, Kimura H, Shinozaki K, Toyoda T, Seki M, Yoshikawa M, Habu Y
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Journal Title
EMBO J
Volume: 29
Pages: 352-362
Related Report
Peer Reviewed
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