Search for New Cancer Cell Growth Pathway
| Project/Area Number |
21570191
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Molecular biology
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| Research Institution | National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East |
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Principal Investigator |
OHTA Tsutomu 独立行政法人国立がん研究センター, 研究所, ユニット長 (10290892)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 転写 / DNAチップ解析 / 細胞増殖 / 癌細胞 |
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| Research Abstract |
The lung cancer is one of intractable cancers, and a tendency to increase has the death rate, the prevalence. Therefore I searched for the new system that participated in cell proliferation of the lung cancer. As a result, I identified that the protein called the transcription factor played an important role in lung cancer cell proliferation. Furthermore, I analyzed the gene expression in tissues and cell lines of breast cancer. As a result, I identified that the protein called the DNA replication factor played an important role in breast cancer cell proliferation.
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Report
(4 results)
Research Products
(11 results)
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[Journal Article] Up-regulation of PSF1 Promotes the Growth of Breast Cancer Cells2010
Author(s)
Nakahara I, Miyamoto M, Shibata T, Akashi-Tanaka S, Mogushi K, Oda K, Ueno M, Takakura N, Mizushima H, Tanaka H, and Ohta T
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Journal Title
Genes Cells
Volume: 15
Issue: 10
Pages: 1015-1024
DOI
Related Report
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