Molecular basis for the regulation of placode differentiation
| Project/Area Number |
21570215
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Developmental biology
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Project Period (FY) |
2009 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 器官形成 / 感覚器 / 神経 / 細胞分化 / 遺伝子 / プラコード / 分化 / シグナル伝達 |
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| Research Abstract |
Molecular mechanisms of placode fate determination in vertebrates were studied. The involvement of FGF and BMP signalings were shown in cultured tissues. Furthermore, the requirement of mutual repression between Pax3 and Pax6 genes in trigeminal placode development were also revealed.
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Report
(4 results)
Research Products
(27 results)
