Development of a novel diagnostic criteria of subclinical endometritis and a program that enhances reproductive functions in postpartum cows

• Project/Area Number: 21580385
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Clinical veterinary science
• Research Institution: Iwate University
• Principal Investigator: OSAWA Takeshi 岩手大学, 農学部, 准教授 (90302059)
• Co-Investigator(Kenkyū-buntansha): HIRATA Toh-ichi 岩手大学, 農学部, 助教 (20241490)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
• Keywords: 臨床繁殖 / 産科 / 乳牛 / 子宮内環境 / 潜在性子宮内膜炎 / 多形核白血球 / 牛 / 子宮内膜炎 / 臨床繁殖学 / サイトブラシ / メトリチェック / 超音波検査 / 腟内留置型プロジェステロン / 排卵同期化処置

Research Abstract

The aim of this study was to establish systematic and objective diagnostic methods of subclinical endometritis in early postpartum Japanese black and Holstein cows. The results of the study suggest that endometrial PMN% could be a suitable parameter for predicting fertility, change in size of the uterine horns by ultrasonography has limitations as a diagnosis for subclinical endometritis, and unsaturated fatty acid supplementation to dairy cows during late dry period may hasten uterine involutions postpartum period.

Research Products

• [Journal Article] Evaluation of reproductive tract infection during early postpartum period and its relationship with subsequent reproductive performance in high-producing dairy cows, Reprod (2012)
  • Author(s): Senosy, W.S., Uchiza, M., Tameoka, N., Izaike, Y., Osawa, T.
  • Journal Title: Dom. Anim. Volume: Vol.47 Pages: 203-207
  • Peer Reviewed
• [Journal Article] Validation of a direct time-resolved fluoroimmunoassay for progesterone in milk from dairy and beef cows (2011)
  • Author(s): Oku, Y., Osawa, T., Hirata, T-I., Kubo, M., Kon, N., Akasaka, S., Senosy, W. S., Takahashi, T., Izaike, Y.
  • Journal Title: Vet. J. Volume: Vol.190 Pages: 244-248
  • Peer Reviewed
• [Journal Article] Reproductive tract defence and disease in postpartum dairy cows (2011)
  • Author(s): LeBlanc, S., Osawa, T., Dubuc, J.
  • Journal Title: Theriogenology Volume: Vol.76 Pages: 1610-1618
  • Peer Reviewed
• [Journal Article] Effect of follicular aspiration at the onset of progesterone-based timed artificial insemination protocol on the follicular dynamics and fertility in early postpartum Japanese black cows (2011)
  • Author(s): Hirata, T-I., Kon, N., Sugiyama, A., Sato, M., Osawa, T.
  • Journal Title: J. Reprod. Dev. Volume: Vol.57 Pages: 613-619
  • Peer Reviewed
• [Journal Article] Effect of Follicular Aspiration at the Onset of Progesterone-based Timed Artificial Insemination on the Follicular Dynamics and Fertility of Early Postpartum Japanese Black Cows (2011)
  • Author(s): Hirata, T-I., Kon, N., Sugiyama, A., Sato, M., Osawa, T.
  • Journal Title: Journal of Reproduction and Development Volume: 57 Issue: 5 Pages: 613-619
  • DOI: 10.1262/jrd.10-130H
  • NAID: 10029878356
  • ISSN: 0916-8818, 1348-4400
  • Peer Reviewed
• [Journal Article] 牛の子宮内膜炎-その実態とコントロール- (2011)
  • Author(s): 大澤健司
  • Journal Title: 日本家畜臨床感染症研究会誌 Volume: 6 Pages: 115-122
• [Presentation] ウシの排卵同期化・定時人工授精プログラムの進化と展望 (2012)
  • Author(s): 大澤健司
  • Organizer: 第153回日本獣医学会学術集会
  • Place of Presentation: 大宮ソニックシティ(埼玉県)(招待講演)
• [Presentation] 高齢黒毛和種牛の卵巣活動およびステロイドホルモン動態の長期観察 (2012)
  • Author(s): 平田統一、赤坂茂、千田広幸、佐々木修一、佐々木修、桃田優子、杉山あかね、昆直樹、佐藤麻衣、伊藤悠紀、大澤健司、青野文仁、加藤修
  • Organizer: 日本畜産学会第115回大会
  • Place of Presentation: 名古屋大学(愛知県)
• [Presentation] 携帯型装置を用いた超音波検査によるウシ子宮内膜炎の診断精度 (2011)
  • Author(s): 大澤健司、Rafael Neves、Stephen LeBlanc
  • Organizer: 第4回日本動物超音波技術研究会大会
  • Place of Presentation: (独)家畜改良センター本所(福島県)
  • Year and Date: 2011-11-07
• [Presentation] Calving season influences on energy metabolites trait, body condition scoring and ovarian resumption in high producing dairy cows. (2011)
  • Author(s): Senosy, W., Osawa, T., Nanae, T., Uchiza, M., Izaike, Y.
  • Organizer: The 15th annual European Society for Domestic Animal Reproduction Conference
  • Place of Presentation: Antalya (Turkey)
• [Presentation] Inflammation and infection of the reproductive tract in dairy cows (2011)
  • Author(s): Osawa, T., Neves, R. C., LeBlanc, S. J.
  • Organizer: Joint Annual Meeting between the American Dairy Science Association and the American Society of Animal Science
  • Place of Presentation: New Orleans (USA)
• [Presentation] Inflammation and infection of the reproductive tract in dairy cows (2011)
  • Author(s): Osawa, T., Neves, R.C., LeBlanc, S.J.
  • Organizer: 2011 Joint Annual Meeting between the American Dairy Science Association and the American Sdciety of Animal Science
  • Place of Presentation: ニューオーリンズ国際会議場(アメリカ合衆国)
• [Presentation] 乳牛の分娩後3週および5週における子宮内膜炎と頸管炎の発生率ならびに腟検査と超音波検査所見との関係 (2011)
  • Author(s): 大澤健司、Rafael Neves、Stephen LeBlanc
  • Organizer: 第152回日本獣医学会学術集会
  • Place of Presentation: 大阪府立大学(大阪府)
• [Presentation] ウシ潜在性子宮内膜炎の迅速診断法の開発 (2011)
  • Author(s): 大澤健司、R.Neves、S.LeBlanc、伊藤瑛基、二俣雅之、平田統一、居在家義昭
  • Organizer: 日本家畜臨床学会第42回学術集会
  • Place of Presentation: ホテル千秋閣(岩手県)
• [Presentation] 牛の子宮内膜炎-その実態とコントロールについて- (2011)
  • Author(s): 大澤健司
  • Organizer: 第1回家畜感染症学会学術集会
  • Place of Presentation: 北海道大学(北海道)(招待講演)
• [Presentation] 乳牛における分娩後の子宮内環境と分娩後5週でのPGF2α製剤投与が繁殖乳成績に及ぼす影響 (2011)
  • Author(s): 山口猛, 大澤健司, 他
  • Organizer: 第151回日本獣医学会学術集会
  • Place of Presentation: 東京農工大学
• [Presentation] Endometrial cytology and vaginal discharge score profiles during PRID-based synchronization program in suckled Japanese black cows (2010)
  • Author(s): Osawa T., Yoshimoto, M., Kon, N., Hirata, T-I., Izaike, Y.
  • Organizer: 26^<th> World Buiatric Congress
  • Place of Presentation: Santiago (Chile)
• [Presentation] 乳牛の分娩後5週目における超音波検査と子宮内膜細胞診の併用による子宮内環境のモニタリング (2010)
  • Author(s): 山口猛, 大澤健司, 他
  • Organizer: 第41回日本家畜臨床学会学術集会
  • Place of Presentation: 山形県天童市天童ホテル
• [Presentation] 分娩後早期の黒毛和種授乳牛における子宮環境モニタリング (2009)
  • Author(s): 大澤健司
  • Organizer: 第148回日本獣医学会
  • Place of Presentation: とりぎん文化会館(鳥取県)
  • Year and Date: 2009-09-25
• [Book] 獣医繁殖学第4版 (2011)
  • Author(s): 居在家義昭、大澤健司, 他
  • Total Pages: 568
  • Publisher: 文永堂出版
• [Book] 牛の繁殖管理における超音波画像診断 (2010)
  • Author(s): 石井一功、磯日出夫、大澤健司, 他
  • Total Pages: 134
  • Publisher: 文永堂出版
• [Book] 子牛の科学 (2009)
  • Author(s): 泉 賢一、板橋久雄、上田宏一郎、遠藤洋、扇勉、大坂郁夫、大澤健司, 他
  • Total Pages: 290
  • Publisher: チクサン出版社
• [Patent(Industrial Property Rights)] 吐出装置 (2010)
  • Inventor(s): 片野圭二,田村孝,大澤健司,小田島尚行,首藤文榮
  • Industrial Property Rights Holder: 岩手大学
  • Patent Publication Number: 2010-279497
  • Filing Date: 2010