| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Research Abstract |
The pyranosides with 2, 3-trans carbamate group anomerized from theβ-to theα-direction under mild acidic conditions. The bond between anomeric carbon and internal oxygen is cleaved and re-cyclized. The generated linear cation is trapped in order to show the evidence of the cleavage pattern. After investigation of the substitutent effect, acetyl group on nitrogen of the carbamate group show the significant effect on the anomerization reaction. Furthermore, the high 1, 2-cis radical C-glycosylation reaction was achieved with pyranosides 2, 3-trans carbamate group.
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