Regulations of oxytocin receptor expression and estrogen action
| Project/Area Number |
21590253
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Environmental physiology (including Physical medicine and Nutritional physiology)
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| Research Institution | University of Fukui |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
NARITA Kazumi 福井大学, 医学部, 助教 (80270958)
ICHIMARU Toru 福井大学, 医学部, 助教 (30452121)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | オキシトシン / オキシトシンレセプター / エストロジェン / エストロジェンレセプター / ラット |
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| Research Abstract |
The oxytocin receptor is regulated by estrogen secreted from the ovary. Using several types of estrogenic compound, the effects of estrogen on the oxytocin receptor were demonstarated to be mediated by several types of estrogen receptor, including classical estrogen receptorsαandβ, and the membrane-associated receptor. In addition, the brain site where estrogen shows an inhibitory effect on food intake was demonstrated in developing female rats.
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Report
(4 results)
Research Products
(5 results)
