Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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Research Abstract |
In the present research, we have revealed that ribosomal protein S19(RP S19) present in normal blood plasma is covalently dimerized by activated factor XIII on the activated platelet surface and gains monocyte chemotactic capacity during blood coagulation process, that the RP S19 dimer recruits monocytes to the coagulum resulting in cellular fibrinolytic absorption of the coagulum, and that monocytotic state of peripheral blood enhance the coagulum resorption process.
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