Novel Marker of oxidative stress by new radical trap agent
| Project/Area Number |
21590633
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Laboratory medicine
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| Research Institution | Kyushu University of Health and Welfare |
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Principal Investigator |
SATO Keizo 九州保健福祉大学, 薬学部, 教授 (00315293)
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| Co-Investigator(Kenkyū-buntansha) |
中川 和子 熊本大学, 大学院・医学薬学研究部, 教授 (20284747)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | 臨床 / 医療・福祉 / 薬学 / 感染症 |
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| Research Abstract |
We found that Novel Marker of oxidative stress by new radical trap agent using our developed new spin trap agent, 5-diphenylphosphoryl-5-methyl-pyrroline-N-Oxide(DPPMPO). It is very useful for free radical detection in not only chemical, cellular, enzymatical system but also in vivo human system by using ESR spin trap extraction method with DPPMPO.
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Report
(4 results)
Research Products
(24 results)
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[Journal Article] Phosphoenoipyruvic Acid, an Intermediary Metabolite of Glycolysis, as a Potential Cytoprotectant and Anti-oxidant in Hela Cells2012
Author(s)
Kondo Y, Ishithuka Y, Kadowaki D, Kuroda M, Tanaka Y, Nagatomi M, Irikura M, Hirata S, Sato K, Maruyama T, Hamasaki N, and Irie T
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Journal Title
Biol. Pharm. Bull
Volume: 35巻
Pages: 1-6
Related Report
Peer Reviewed
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[Journal Article] Phosphoenoipyruvic Acid, an Intermediary Metabolite of Glycolysis, as a Potential Cytoprotectant and Anti-oxidant in Hela Cells2012
Author(s)
Kondo Y, Ishithuka Y, Kadowaki D, Kuroda M, Tanaka Y, Nagatomi M, Irikura M, Hirata S, Sato K., Maruyama T, Hamasaki N, Irie T
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Journal Title
Biol.Pharm.Bull
Volume: 35
Pages: 1-6
Related Report
Peer Reviewed
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