Analysis on DNA methylation profiles in forensic evidence
| Project/Area Number |
21590742
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Legal medicine
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| Research Institution | Iwate Medical University |
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Principal Investigator |
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | DNAメチル化 / 経時変化 / DNA多型 / ethnicity / ハプロタイプ / H19 / 日本人特異的 / 遺伝子 / 個人識別 / エスニック由来 |
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| Research Abstract |
1.Methylation status in forensic evidences under eight different environmental conditions(temperature, humidity, light etc.) was analyzed, however, no significant difference was observed.
2.A haplotype polymorphism composed of 23 SNPs upstream of the H19 gene was investigated, and 21 haplotypes including several ethnicity-specific haplotypes were observed from nine ethnic groups.
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Report
(4 results)
Research Products
(14 results)
