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Analysis on DNA methylation profiles in forensic evidence

Research Project

Project/Area Number 21590742
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Legal medicine
Research InstitutionIwate Medical University

Principal Investigator

NAKAYASHIKI Nori  岩手医科大学, 医学部, 講師 (10146029)

Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
KeywordsDNAメチル化 / 経時変化 / DNA多型 / ethnicity / ハプロタイプ / H19 / 日本人特異的 / 遺伝子 / 個人識別 / エスニック由来
Research Abstract

1.Methylation status in forensic evidences under eight different environmental conditions(temperature, humidity, light etc.) was analyzed, however, no significant difference was observed.
2.A haplotype polymorphism composed of 23 SNPs upstream of the H19 gene was investigated, and 21 haplotypes including several ethnicity-specific haplotypes were observed from nine ethnic groups.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (14 results)

All 2011 2010 2009

All Journal Article (6 results) (of which Peer Reviewed: 4 results) Presentation (8 results)

  • [Journal Article] H19インプリント遺伝子のハプロタイプ分析~22011

    • Author(s)
      中屋敷徳, 出羽厚二, 湯浅勲, 山本敏充
    • Journal Title

      DNA多型

      Volume: 19 Pages: 151-154

    • NAID

      10029668793

    • Related Report
      2011 Final Research Report
  • [Journal Article] The distribution of H19HP haplotypes in Asian populations2011

    • Author(s)
      Nakayashiki N, Fujita M, Dewa K, Ding M, Wei W, Wang X, Yamamoto T, Yuasa I
    • Journal Title

      Forens. Sci. Int. Genet. Suppl. Ser

      Volume: 3

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] The distribution of H19HP haplotypes in Asian populations2011

    • Author(s)
      Nori Nakayashiki
    • Journal Title

      Forensic Science International : Genetics Supplement Series

      Volume: 3 Issue: 1 Pages: e341-e342

    • DOI

      10.1016/j.fsigss.2011.09.033

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] H19インプリント遺伝子のハプロタイプ分析22011

    • Author(s)
      中屋敷徳, 他
    • Journal Title

      DNA多型

      Volume: 19(印刷中)

    • NAID

      10029668793

    • Related Report
      2010 Annual Research Report
  • [Journal Article] Investigation of SNP haplotypes in the H19 imprinted gene2009

    • Author(s)
      Nakayashiki N, Shimamoto K, Takamiya M, Hashiyada M, Yuasa I, Dewa K
    • Journal Title

      Forens. Sci. Int. Genet. Suppl. Ser

      Volume: 2 Pages: 540-541

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Investigation of SNP haplotypes in the H19 imprinted gene2009

    • Author(s)
      Nori Nakayashiki
    • Journal Title

      Forens Sci Int : Genet Supplement Series 2

      Pages: 540-541

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] The distribution of H19HP haplotypes in Asian populations2011

    • Author(s)
      Nakayashiki N, Fujita M, Dewa K, Ding M, Wei W, Wang X, Yamamoto T, Yuasa I
    • Organizer
      The 24^<th> World Congress of the International Society for Forensic Genetics
    • Place of Presentation
      Vienna, Austria
    • Year and Date
      2011-09-01
    • Related Report
      2011 Final Research Report
  • [Presentation] The distribution of H19HP haplotypes in Asian populations2011

    • Author(s)
      Nori Nakayashiki
    • Organizer
      24^<th> World Congress International Society for Forensic Genetics
    • Place of Presentation
      Vienna, Austria
    • Year and Date
      2011-09-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] H19インプリント遺伝子のハプロタイプ分析22010

    • Author(s)
      中屋敷徳, 他
    • Organizer
      第19回日本DNA多型学会学術集会
    • Place of Presentation
      三島
    • Year and Date
      2010-11-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] H19インプリント遺伝子のハプロタイプ分析~22010

    • Author(s)
      中屋敷徳, 出羽厚二, 湯浅勲, 山本敏充
    • Organizer
      日本DNA多型学会第19回学術集会
    • Place of Presentation
      三島
    • Year and Date
      2010-11-18
    • Related Report
      2011 Final Research Report
  • [Presentation] H19インプリント遺伝子上流のSNPハプロタイプ分析2010

    • Author(s)
      中屋敷徳, 高宮正隆, 橋谷田真樹, 湯浅勲, 山本敏充, 出羽厚二
    • Organizer
      日本法医学会総会
    • Place of Presentation
      東京
    • Year and Date
      2010-06-25
    • Related Report
      2011 Final Research Report
  • [Presentation] H19インプリント遺伝子上流のSNP-ハプロタイプ分析2010

    • Author(s)
      中屋敷徳, 他
    • Organizer
      第94次日本法医学会総会
    • Place of Presentation
      東京
    • Year and Date
      2010-06-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] Investigation of SNP haplotypes in the H19 imprinted gene2009

    • Author(s)
      Nakayashiki N, Shimamoto K, Takamiya M, Hashiyada M, Yuasa I, Dewa K
    • Organizer
      The 23^<rd> World Congress of the International Society for Forensic Genetics
    • Place of Presentation
      Buenos Aires, Argentina
    • Year and Date
      2009-09-18
    • Related Report
      2011 Final Research Report
  • [Presentation] Investigation of SNP haplotypes in the H19 imprinted gene2009

    • Author(s)
      Nori Nakayashiki
    • Organizer
      23^<rd> World Congress International Society for Forensic Genetics
    • Place of Presentation
      Buenos Aires, Argentina
    • Year and Date
      2009-09-18
    • Related Report
      2009 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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