| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Research Abstract |
One hundred three subjects were registered in this study until March 31, 2014. Hypertension was found in 45. It was shown that linear hyperintensities in the cerebral white matter (LH-WM) was negatively correlated with volume and positively correlated with number of silent lacunar infarcts. Linear hyperintensities in the basal ganglia (LH-BG) was positively correlated with number of lacunar infarcts. Both LHs was not correlated with results of neuropsychological tests. It is suggested that LH-WM and LH-BG have relationship with aging and brain volume. Since silent lacunar infarct has a link with symptomatic stroke and cognitive impairment, both LHs have a potential of clinical significance. Further analyses needs to include results of serum biomarkers, to use multivariate statistical method. We also need to add number of subjects for statistical power.
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