Imaging of proliferative ability and hypoxia of tumor in radioimmunotherapy

• Project/Area Number: 21591580
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Radiation science
• Research Institution: Kinki University
• Principal Investigator: HOSONO Makoto 近畿大学, 医学部附属病院, 教授 (00281303)
• Project Period (FY): 2009 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000); Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
• Keywords: 放射免疫療法 / 低酸素 / 悪性リンパ腫 / 抗原抗体 / 陽電子断層撮影 / 単光子断層撮影 / FDG / 低酸素イメージング

Research Abstract

In patients with CD20 positive B-cell non-Hodgkin lymphoma who underwent yttrium-90 labeled anti-CD20 ibritumomab tiuxetan therapy, glucose metabolism by FDG and hypoxia by FMISO were evaluated with PET/CT before and after therapy, and changes were analyzed over time. Antigen expression of CD20 was also evaluated by SPECT/CT using indium-111 labeled anti-CD20 antibody. Association of glucose metabolism, hypoxia, and CD20 expression with therapeutic response was analyzed.

Research Products

• [Journal Article] Dynamic sequence respiratory gated perfusion pulmonary SPECT without external tracking device (2013)
  • Author(s): Sakaguchi K, Hosono M, Otsuka M, Hanaoka K, Usami K, Uto T, Ishii K
  • Journal Title: Ann Nucl Med Volume: 27(1) Pages: 65-73
  • NAID: 10031168069
  • Peer Reviewed
• [Journal Article] A Prospective Clinical Trial of Tumor Hypoxia Imaging with 18F-fluoromisonidazole Positron Emission Tomography and Computed Tomography (F-MISO PET/CT) before and during Radiation Therapy (2013)
  • Author(s): Tachibana I, Nishimura Y, Shibata T, Kanamori S, Nakamatsu K, Koike R, Nishikawa T, Ishikawa K, Tamura M, Hosono M
  • Journal Title: J Radiation Research Volume: (in press)
  • Peer Reviewed
• [Journal Article] Dynamic sequence respiratory gated perfusion pulmonary SPECT without external tracking device (2013)
  • Author(s): Sakaguchi K
  • Journal Title: Ann Nucl Med Volume: 27 Pages: 65-73
  • Peer Reviewed
• [Journal Article] A Prospective Clinical Trial of Tumor Hypoxia Imaging with 18F-fluoromisonidazole Positron Emission Tomography and Computed Tomography (F-MISO PET/CT) before and during Radiation Therapy (2013)
  • Author(s): Tachibana I
  • Journal Title: J Radiat Research Volume: -
  • Peer Reviewed
• [Journal Article] The iliac wing sign: an indicator of the presence of bone and/or soft-tissue injury of the pelvis and hips (2012)
  • Author(s): Kakigi T, Hosono M, Taro Shimono T, Hiraoka T, Nishimura K
  • Journal Title: European Journal of Radiology Volume: 81 Pages: 2348-2352
  • Peer Reviewed
• [Journal Article] Impact of CT attenuation correction by SPECT/CT in brain perfusion images (2012)
  • Author(s): Ishii K, Hanaoka K, Okada M, Kumano S, Komeya Y, Tsuchiya N, Hosono M, Murakami T
  • Journal Title: Ann Nucl Med Volume: 26(3) Pages: 241-247
  • NAID: 10030623855
  • Peer Reviewed
• [Journal Article] Recognition of complete response by long-term observation after treatment with 90Y-Ibritumomab tiuxetan for relapsed follicular lymphoma (2012)
  • Author(s): Tatsumi Y, Rai S, Shimada T, Yamaguchi K, Morita Y, Kawanishi K, Miyatake J, Ashida T, Hosono M, Matsumura I
  • Journal Title: Acta Med Kinki Univ Volume: 36(2) Pages: 87-89
  • Peer Reviewed
• [Journal Article] Recognition of complete response by long-term observation after treatment with 90Y-Ibritumomab tiuxetan for relapsed follicular lymphoma (2012)
  • Author(s): Tatsumi Y
  • Journal Title: Acta Med Kinki Univ Volume: 36 Pages: 87-89
  • Peer Reviewed
• [Journal Article] Impact of CT attenuation correction by SPECT/CT in brain perfusion images (2012)
  • Author(s): Ishii K
  • Journal Title: Ann Nucl Med Volume: 26 Pages: 241-247
  • Peer Reviewed
• [Journal Article] 脳FDG集積低下を示す大きな腫瘍代謝症例の分析 (2012)
  • Author(s): 細野眞
  • Journal Title: 核医学症例検討会症例集 Volume: 32(2) Pages: 11-12
• [Journal Article] FDG uptake in bone marrow after G-CSF administration in patients with non-Hodgkin lymphoma (2011)
  • Author(s): Hanaoka K, Hosono M, Tatsumi Y, 6) Komeya Y, Tsuchiya N, Usami K, Yuzuru Y, Ishii K, Sumita M
  • Journal Title: Nucl Med Commun Volume: 32(8) Pages: 678-683
  • Peer Reviewed
• [Journal Article] FDG uptake in bone marrow after G-CSF administration in patients with non-Hodgkin lymphoma (2011)
  • Author(s): Hanaoka K
  • Journal Title: Nucl Med Commun Volume: 32 Issue: 8 Pages: 678-683
  • DOI: 10.1097/mnm.0b013e328346b32a
  • Peer Reviewed
• [Journal Article] The iliac wing sign : an indicator of the presence of bone and/or soft-tissue injury of the pelvis and hips (2011)
  • Author(s): Kakigi T
  • Journal Title: European Journal of Radiology Volume: Sep 9(Epub ahead of print)(EPub)
  • Peer Reviewed
• [Journal Article] ガラスバッジを用いた単純X線撮影における患者被ばく線量の測定 (2011)
  • Author(s): 宇佐美公男
  • Journal Title: 日本放射線技術学会雑誌 Volume: 67(7) Pages: 785-792
  • Peer Reviewed
• [Journal Article] Fourth ventricular mixed germ cell tumor demonstrating adipose tissue in a young adult (2010)
  • Author(s): Kuriu A, Shimono T, Kuwabara M, Ashikaga R, Hosono M, Murakami T
  • Journal Title: Jpn J Radiol Volume: 28 Pages: 166-168
  • NAID: 50007498094
  • Peer Reviewed
• [Journal Article] Radiation treatment planning using positron emission and computed tomography for lung pharyngeal cancers: a multiple-threshold method for [18F]fluoro-2-deoxyglucose activity (2010)
  • Author(s): Okubo M, Nishimura Y, Nakamatsu K, Okumura M, Shibata T, Kanamori S, Hanaoka K, Hosono M
  • Journal Title: Int J Radiation Oncology Biol Phys Volume: 77:2 Pages: 350-356
  • Peer Reviewed
• [Journal Article] FDG PET/CT versus CT, MR imaging, and 67Ga scintigraphy in the posttherapy evaluation of malignant lymphoma (2010)
  • Author(s): Okada M, Sato N, Ishii K, Matsumura K, Hosono M, Murakami T
  • Journal Title: Radiographics Volume: 30(4) Pages: 939-57
  • Peer Reviewed
• [Journal Article] Decreased brain FDG uptake in patients with extensive non-Hodgkin's lymphoma lesions (2010)
  • Author(s): Hanaoka K, Hosono M, Shimono T, Usami K, Komeya Y, Tsuchiya N, Yamazoe Y, Ishii K, Tatsumi Y, Sumita M
  • Journal Title: Ann Nucl Med Volume: 24 Pages: 707-711
  • NAID: 10027659660
  • Peer Reviewed
• [Journal Article] Decreased brain FDG uptake in patients with extensive non-Hodgkin's lymphoma lesions (2010)
  • Author(s): Hanaoka K, 他
  • Journal Title: Ann Nucl Med Volume: 2010 Pages: 707-711
  • Peer Reviewed
• [Journal Article] FDG PET/CT versus CT, MR imaging, and 67Ga scintigraphy in the posttherapy evaluation of malignant lymp homa (2010)
  • Author(s): Okada M, 他
  • Journal Title: Radiographics Volume: 30 Pages: 939-957
  • Peer Reviewed
• [Journal Article] Radiation treatment planning using positron emission and computed tomography for lung pharyngeal cancers : a multiple-threshold method for [18F]fluoro-2-deoxyglucose activity (2010)
  • Author(s): Okubo M, 他
  • Journal Title: Int J Radiation Oncology Biol Phys Volume: 77 Pages: 350-356
  • Peer Reviewed
• [Journal Article] Fourth ventricular mixed germ cell tumor demonstrating adipose tissue in a young adult (2010)
  • Author(s): Kuriu A, 他
  • Journal Title: Radiographics Volume: 30 Pages: 939-957
  • Peer Reviewed
• [Journal Article] Demonstration of cerebellar atrophy in neuroacanthocytosis of 2 siblings (2009)
  • Author(s): Katsube T, Shimono T, Ashikaga R, Hosono M, Kitagaki H, Murakami T
  • Journal Title: AJNR Am J Neuroradiol Volume: 30: 2 Pages: 386-8
  • Peer Reviewed
• [Journal Article] Integrated FDG-PET/CT compared with intravenous contrast enhanced CT for evaluation of metastatic regional lymph nodes in patients with resectable early stage esophageal cancer (2009)
  • Author(s): Okada M, Murakami T, Kumano S, Kuwabara M, Shimono T, Hosono M, Shiozaki H
  • Journal Title: Ann Nucl Med Volume: 23:1 Pages: 73-80
  • NAID: 10025135379
  • Peer Reviewed
• [Journal Article] Ring-shaped lateral ventricular nodules: an incidental finding on brain magnetic resonance imaging (2009)
  • Author(s): Shimono T, Hosono M, Ashikaga R, Kumano S, Imaoka I, Yagyu Y, Okada M, Kuwabara M, Murakami T
  • Journal Title: Neuroradiology Volume: 51:3 Pages: 145-150
  • Peer Reviewed
• [Journal Article] Adrenal masses: the value of additional fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) in differentiating between benign and malignant lesions (2009)
  • Author(s): Okada M, Shimono T, Komeya Y, Ando R, Kagawa Y, Katsube T, Kuwabara M, Yagyu Y, Kumano S, Imaoka I, Tsuchiya N, Ashikaga R, Hosono M, Murakami T
  • Journal Title: Ann Nucl Med Volume: 23(4) Pages: 349-354
  • NAID: 10025136357
  • Peer Reviewed
• [Journal Article] Adrenal masses : the value of additional fluorodeoxyglucose-positron emission tomography/computed tomography(FDG-PET/CT)in differentiating between benign and malignant lesions (2009)
  • Author(s): Okada M, 他
  • Journal Title: Ann Nucl Med 23 Pages: 349-354
  • Peer Reviewed
• [Journal Article] Demonstration of cerebellar atrophy in neuroacanthocytosis of 2 siblings (2009)
  • Author(s): Katsube T, 他
  • Journal Title: AJNR Am J Neuroradiol 30 Pages: 386-388
  • Peer Reviewed
• [Journal Article] Integrated FDG-PET/CT compared with intravenous contrast enhanced CT for evaluation of metastatic regional lymph nodes in patients with resectable early stage esophageal cancer (2009)
  • Author(s): Okada M, 他
  • Journal Title: Ann Nucl Med 23 Pages: 73-80
  • Peer Reviewed
• [Journal Article] Ring-shaped lateral ventricular nodules : an incidental finding on brain magnetic resonance imaging (2009)
  • Author(s): Shimono T, 他
  • Journal Title: Neuroradiology 51 Pages: 145-150
  • Peer Reviewed
• [Journal Article] 放射免疫療法の歴史と将来展望 (2009)
  • Author(s): 細野眞, 他
  • Journal Title: 血液フロンティア 19 Pages: 99-105
• [Journal Article] イットリウム-90標識抗CD20抗体(ゼヴァリン)による治療 (2009)
  • Author(s): 細野眞
  • Journal Title: 医学物理 29;Suppl 4 Pages: 1-17
• [Journal Article] 医療における放射線防護の国際動向 (2009)
  • Author(s): 細野眞, 他
  • Journal Title: 臨床放射線 54 Pages: 1772-1778
  • NAID: 40016921939
• [Journal Article] X線診療施設の遮へい評価法に関する調査研究 (2009)
  • Author(s): 大場久照, 他
  • Journal Title: 日本放射線技術学会雑誌 65 Pages: 57-63
  • Peer Reviewed
• [Presentation] Prediction of tumor response by Indium-111-Zevalin SPECT/CT and FDG-PET/CT in radioimmunotherapy for B-cell non-Hodgkin lymphoma (2012)
  • Author(s): Hosono M, Hanaoka K, Ishii K, Sakaguchi K, Im S, Tsuchiya N, Komeya Y, Yagyu Y, Tatsumi Y, Matsumura I
  • Organizer: Annual Congress of European Association of Nuclear Medicine
  • Place of Presentation: Milan, Italy
• [Presentation] Three dimensional planning of radioiodine therapy for hyperthyroidism by iodine-123 SPECT/CT (2012)
  • Author(s): Hanaoka K, Hosono M, Kurokawa T, Sakaguchi K, Yoshida S, Inoue R, Ishii K, Murakami T
  • Organizer: Annual Congress of European Association of Nuclear Medicine
  • Place of Presentation: Milan, Italy
• [Presentation] Prediction of tumor response by Indium-111-Zevalin SPECT/CT and FDG-PET/CT in radioimmunotherapy for B-cell non-Hodgkin lymphoma (2012)
  • Author(s): Hosono M
  • Organizer: Annual Congress of European Association of Nuclear Medicine
  • Place of Presentation: Milano(Italia)
• [Presentation] Three dimensional planning of radioiodine therapy for hyperthyroidism by iodine-123 SPECT/CT (2012)
  • Author(s): Hanaoka K
  • Organizer: Annual Congress of European Association of Nuclear Medicine
  • Place of Presentation: Milano(Italia)
• [Presentation] Radiation Protection in PET/CT (2012)
  • Author(s): Hosono M
  • Organizer: International conference on radiation protection in medicine IAEA
  • Place of Presentation: Bonn(Germany)
  • Invited
• [Presentation] Overview of Radiation Protection in Radionuclide Therapy (2012)
  • Author(s): Hosono M
  • Organizer: International conference on radiation protection in medicine IAEA
  • Place of Presentation: Bonn(Germany)
  • Invited
• [Presentation] Radiation safety in Nuclear Medicine (2012)
  • Author(s): Hosono M
  • Organizer: 11th Annual General Meeting of Asian Regional Cooperative Council for Nuclear Medicine
  • Place of Presentation: Seoul(South Korea)
  • Invited
• [Presentation] Chronological Documents on the Fukushima Accident-Nuclear Emergency at the Fukushima Nuclear Reactor Accident in March (2012)
  • Author(s): Hosono M
  • Organizer: Annual Meeting of Society of Nuclear Medicine
  • Place of Presentation: Miami(USA)
  • Invited
• [Presentation] 核医学治療の実践と展望 (2011)
  • Author(s): 細野眞
  • Organizer: 第45回宮崎県核医学研究会
  • Place of Presentation: 宮崎市宮崎観光ホテル
  • Year and Date: 2011-11-18
• [Presentation] 子どもたちの未来のために-川俣町と近畿大学- (2011)
  • Author(s): 細野眞
  • Organizer: 第11回近畿放射線医学フォーラム
  • Place of Presentation: 大阪市シェラトン都ホテル大阪
  • Year and Date: 2011-10-15
• [Presentation] PETの癌治療への応用 (2011)
  • Author(s): 細野眞
  • Organizer: 第3回京都癌PETカンファレンス
  • Place of Presentation: 京都市上京区青蓮会館
  • Year and Date: 2011-10-06
• [Presentation] PET/CTとSPECT/CTによる悪性リンパ腫の核医学診断 (2011)
  • Author(s): 細野眞
  • Organizer: 悪性リンパ腫に関する学術講演会2011
  • Place of Presentation: 東京都千代田区経団連会館
  • Year and Date: 2011-09-10
• [Presentation] 被災者の健康管理への配慮～正当化と最適化～ (2011)
  • Author(s): 細野眞
  • Organizer: 10回規制科学ダイアログセミナー
  • Place of Presentation: 東京都中央区ベルサール八重洲
  • Year and Date: 2011-09-03
• [Presentation] 最新のアイソトープ治療 (2011)
  • Author(s): 細野眞
  • Organizer: 平成23年度大学等における放射線安全管理研修会
  • Place of Presentation: 東京大学安田講堂
  • Year and Date: 2011-08-26
• [Presentation] 放射線の健康への影響 (2011)
  • Author(s): 細野眞
  • Organizer: 川俣町町民講座
  • Place of Presentation: 福島県川俣町
  • Year and Date: 2011-06-21
• [Presentation] 機能画像に基づくがん治療-機能画像の臨床応用 (2011)
  • Author(s): 細野眞
  • Organizer: 第13回癌治療増感研究会シンポジウム
  • Place of Presentation: 奈良市
  • Year and Date: 2011-02-11
• [Presentation] The iliac wing sign: The feasibility for diagnosis of bone and/or soft-tissue injury of the pelvis and hips (2011)
  • Author(s): Kakigi T, Hosono M, Shimono T, Hiraoka T, Nishimura K
  • Organizer: ECR 2011
  • Place of Presentation: Vienna, Austria
• [Presentation] A prospective Clinical Trial on Tumor Hypoxia Imaging with 18F-misonidazole (F-MISO) positron Emission Tomography (PET) (2011)
  • Author(s): Tachibana I, Nishimura Y, Shibata T, Kanamori S, Nakamatsu K, Tamura M, Koike R, Nishikawa T, Ishikawa K, Hosono M
  • Organizer: 53rd annual meeting of ASTRO
  • Place of Presentation: Miami, Florida, USA
• [Presentation] Indium-111-Zevalin-SPECT/CT and FDG-PET/CT as quantitative evaluation in radioimmunotherapy for B-cell non-Hodgkin's lymphoma (Abstract: P706) (2011)
  • Author(s): Hanaoka K, Hosono M, Yamazoe Y, Tatsumi Y, Komeya Y, Tsuchiya N, Ishii K, Usami K, Murakami T, Uto T
  • Organizer: EANM' 11 annual congress of European Society of Nuclear Medicine
  • Place of Presentation: Birmingham, UK
• [Presentation] Measurement of functional thyroid weight using I-123 SPECT/CT as planning for radioiodine therapy (Abstract: PW034) (2011)
  • Author(s): Hanaoka K, Hosono M, Shimosegawa E, Hatazawa J
  • Organizer: EANM' 11 annual congress of European Society of Nuclear Medicine
  • Place of Presentation: Birmingham, UK
• [Presentation] A prospective Clinical Trial on Tumor Hypoxia Imaging with 18F-misonidazole (F-MISO) positron Emission Tomography (PET) (2011)
  • Author(s): Tachibana I
  • Organizer: 53rd annual meeting of ASTRO
  • Place of Presentation: Miami, Fiorida, USA
• [Presentation] Indium-111-Zevalin-SPECT/CT and FDG-PET/CT as quantitative evaluation in radioimmunotherapy for B-cell non-Hodgkin's lymphoma (Abstract : P706) (2011)
  • Author(s): Hanaoka K
  • Organizer: EANM' 11 annual congress of European Society of Nuclear Medicine
  • Place of Presentation: Birmingham, UK
• [Presentation] Measurement of functional thyroid weight using I-123 SPECT/CT as planning for radioiodine therapy (Abstract : PW034) (2011)
  • Author(s): Hanaoka K
  • Organizer: EANM' 11 annual congress of European Society of Nuclear Medicine
  • Place of Presentation: Birmingham, UK
• [Presentation] I-131の安全取り扱いI-131(1,110MBq)による残存甲状腺破壊(アブレーション)の外来治療における適正使用 (2011)
  • Author(s): 細野眞
  • Organizer: 第11回日本核医学会春季大会
  • Place of Presentation: 大阪国際交流センター大阪市
• [Presentation] RI治療の治療の概要 (2011)
  • Author(s): 細野眞
  • Organizer: 第11回日本核医学会春季大会
  • Place of Presentation: 大阪国際交流センター大阪市
• [Presentation] ガイドライン(検査、センチネル、オムツ、他) (2011)
  • Author(s): 細野眞
  • Organizer: 第11回日本核医学会春季大会
  • Place of Presentation: 大阪国際交流センター大阪市
• [Presentation] 核医学治療の有効性と環境整備および今後の展望 (2011)
  • Author(s): 細野眞
  • Organizer: 第51回日本核医学会学術総会
  • Place of Presentation: 茨城県つくば市つくば国際会議場
• [Presentation] The iliac wing sign : The feasibility for diagnosis of bone and/or soft-tissue injury of the pelvis and hips (2011)
  • Author(s): Kakigi T, 他
  • Organizer: ECR 2011
  • Place of Presentation: Vienna, Austria
• [Presentation] RI内照射療法の併用療法と今後の展望 シンポジウム RI内用療法の臨床利用の発展をめざして (2010)
  • Author(s): 細野眞
  • Organizer: 第50回日本核医学会学術総会
  • Place of Presentation: 大宮ソニックシティ さいたま市
  • Year and Date: 2010-11-12
• [Presentation] 機能画像を用いた放射線治療計画の現状と展望 シンポジウム 放射線治療に貢献するPET/CTの展望 (2010)
  • Author(s): 西村恭昌
  • Organizer: 第50回日本核医学会学術総会
  • Place of Presentation: 大宮ソニックシティ さいたま市
  • Year and Date: 2010-11-12
• [Presentation] 放射線治療計画におけるPETデータの活用シンポジウムFDG・PET Today and Tomorrow (2010)
  • Author(s): 細野眞
  • Organizer: PETサマーセミナー2010in岡山
  • Place of Presentation: ホテルグランヴィア岡山
  • Year and Date: 2010-08-21
• [Presentation] 日本における医療放射線安全の取り組み (2010)
  • Author(s): 細野眞
  • Organizer: 第66回日本放射線技術学会総会学術大会
  • Place of Presentation: パシフィコ横浜(教育講演)
  • Year and Date: 2010-04-10
• [Presentation] FDG uptake in bone marrow after G-CSF administration in patients with non-Hodgkin lymphoma (2010)
  • Author(s): Hanaoka K, Hosono M, Komeya Y, Tsuchiya N, Usami k, Yamazoe Y, Ishii K, Tatsumi Y, Murakami T
  • Organizer: Abstract#P502, EANM'10
  • Place of Presentation: Vienna, Austria
• [Presentation] Indium-111-Zevalin and FDG uptake in association with tumor response in radioimmunotherapy for B-cell non-Hodgkin's lymphoma (2010)
  • Author(s): Hanaoka K, Hosono M, Yamazoe Y, Komeya Y, Tsuchiya N, Usami K, Sumita M, Tatsumi Y
  • Organizer: Abstract#P726, EANM'10
  • Place of Presentation: Vienna, Austria
• [Presentation] Definition of target volumes by PET/CT for radiation therapy planning using moving phantom (2010)
  • Author(s): Hanaoka K, Hosono M, Okubo M, Usami K, Okumura M, Sumita M, Nishimura Y, Murakami T
  • Organizer: Abstract#TP10, EANM'10
  • Place of Presentation: Vienna, Austria
• [Presentation] 医療放射線被ばくとその防護 核医学基礎セミナー (2010)
  • Author(s): 細野眞
  • Organizer: 第10回日本核医学会春季大会
  • Place of Presentation: タワーホール船堀 東京都江戸川区
• [Presentation] PET-CT核医学指導者コース (2010)
  • Author(s): 細野眞
  • Organizer: 第10回日本核医学会春季大会
  • Place of Presentation: タワーホール船堀 東京都江戸川区
• [Presentation] FDG uptake in bone marrow after G-CSF administration in patients with non-Hodgkin lymphoma (2010)
  • Author(s): Hanaoka K, 他
  • Organizer: EANM'10
  • Place of Presentation: Vienna, Austria
• [Presentation] Indium-111-Zevalin and FDG uptake in association with tumor response in radioimmunotherapy for B-cell non-Hodgkin's lymphoma (2010)
  • Author(s): Hanaoka K, 他
  • Organizer: EANM'10
  • Place of Presentation: Vienna, Austria
• [Presentation] Definition of target volumes by PET/CT for radiation therapy planning using moving phantom (2010)
  • Author(s): Hanaoka K, 他
  • Organizer: EANM'10
  • Place of Presentation: Vienna, Austria
• [Presentation] 90Yゼヴァリンによる悪性リンパ腫の治療 (2009)
  • Author(s): 細野眞
  • Organizer: 第1回関西核医学治療研究会
  • Place of Presentation: 千里ライフサイエンスセンター(大阪)
  • Year and Date: 2009-11-21
• [Presentation] 内照射療法の基礎と臨床 (2009)
  • Author(s): 細野眞
  • Organizer: 第49回日本核医学会学術総会 教育講演
  • Place of Presentation: 旭川文化会館(旭川)
  • Year and Date: 2009-10-02
• [Presentation] イットリウム-90標識抗CD20抗体(ゼヴァリン)による治療 (2009)
  • Author(s): 細野眞
  • Organizer: 第22回日本放射線腫瘍学会学術大会
  • Place of Presentation: 京都国際会館(京都)
  • Year and Date: 2009-09-17
• [Presentation] ゼヴァリンによる放射免疫療法の実践 (2009)
  • Author(s): 細野眞
  • Organizer: 第10回腫瘍核医学セミナー
  • Place of Presentation: 新大阪ワシントンプラザ(大阪)
  • Year and Date: 2009-08-07
• [Presentation] 核医学を用いた新しい治療 (2009)
  • Author(s): 細野眞
  • Organizer: 放射線科専門医会・医会2009年度ミッドサマーセミナー
  • Place of Presentation: ポートピアホテル(神戸)
  • Year and Date: 2009-07-18
• [Presentation] 医療放射線の最適化 (2009)
  • Author(s): 細野眞
  • Organizer: 日本保健物理学会第43回研究発表会
  • Place of Presentation: 都ホテル(大阪)
  • Year and Date: 2009-06-04
• [Presentation] PET-CT 核医学指導者コース (2009)
  • Author(s): 細野眞
  • Organizer: 第9回日本核医学会春季大会
  • Place of Presentation: タワーホール船堀(東京)
  • Year and Date: 2009-05-10
• [Presentation] Zevalin による放射免疫療法の実際 (2009)
  • Author(s): 細野眞
  • Organizer: 第45回腫瘍・免疫核医学研究会
  • Place of Presentation: タワーホール船堀(東京)
  • Year and Date: 2009-05-09
• [Presentation] 医療放射線被ばくとその防護 核医学基礎セミナー (2009)
  • Author(s): 細野眞
  • Organizer: 第9回日本核医学会春季大会
  • Place of Presentation: タワーホール船堀(東京)
  • Year and Date: 2009-05-09
• [Presentation] Measurement of regional cerebral blood flow associated with cilostazol therapy in vascular dementia (2009)
  • Author(s): Hanada K, Hosono M, Hitomi Y, Tsuchiya N, Komeya Y, Tsujii N, Kitahata D, Takahashi E, Murakami T
  • Organizer: 56th annual meeting of Society of Nuclear Medicine
  • Place of Presentation: Toronto, Canada
• [Presentation] Assessment of lymph node metastasis esophageal cancer with SUV correction based on count recovery on 18F-FDG (2009)
  • Author(s): Komeya Y, Hosono M, Tsuchiya N, Okada M, Kagawa Y, Hanaoka K, Usami K, Yamazoe Y, Murakami T, Itoh T
  • Organizer: 56th annual meeting of Society of Nuclear Medicine
  • Place of Presentation: Toronto, Canada
• [Presentation] Decreased brain FDG uptake in patients with FDG-avid non-Hodgkin lymphoma lesions (2009)
  • Author(s): Hanaoka K, Hosono M, Shimono T, Komeya Y, Tsuchiya N, Usami K, Yamazoe Y, Sumita M, Itoh T
  • Organizer: 56th annual meeting of Society of Nuclear Medicine
  • Place of Presentation: Toronto, Canada
• [Presentation] FDG uptake in bone marrow after G-CSF administration in patients with non-Hodgkin lymphoma (2009)
  • Author(s): Hanaoka K, Hosono M, Komeya Y, Tsuchiya N, Ohata A, Usami K, Yamazoe Y, Sumita M, Itoh T
  • Organizer: 56th annual meeting of Society of Nuclear Medicine
  • Place of Presentation: Toronto, Canada
• [Presentation] Characteristics of FDG biodistribution in chronic hemodialysis patients (2009)
  • Author(s): Hanaoka K, Hosono M, Komeya Y, Ohata A, Usami K, Tsuchiya N, Yamazoe Y, Sumita M, Shimono T, Itoh T
  • Organizer: 56th annual meeting of Society of Nuclear Medicine
  • Place of Presentation: Toronto, Canada
• [Presentation] Characteristics of FDG biodistribution in chronic hemodialysis patients (2009)
  • Author(s): Hanaoka K, 他
  • Organizer: Society of Nuclear Medicine
  • Place of Presentation: Toronto
• [Presentation] FDG uptake in bone marrow after G-CSF administration in patients with non-Hodgkin lymphoma (2009)
  • Author(s): Hanaoka K, 他
  • Organizer: Society of Nuclear Medicine
  • Place of Presentation: Toronto
• [Presentation] Decreased brain FDG uptake in patients with FDG-avid non-Hodgkin lymphoma lesions (2009)
  • Author(s): Hanaoka K, 他
  • Organizer: Society of Nuclear Medicine
  • Place of Presentation: Toronto
• [Presentation] Assessment of lymph node metastasis esophageal cancer with SUV correction based on count recovery on 18F-FDG (2009)
  • Author(s): Komeya Y, 他
  • Organizer: Society of Nuclear Medicine
  • Place of Presentation: Toronto
• [Presentation] Measurement of regional cerebral blood flow associated with cilostazol therapy in vascular dementia (2009)
  • Author(s): Hanada K, 他
  • Organizer: Society of Nuclear Medicine
  • Place of Presentation: Toronto
• [Book] 医療放射線の安全確保と有効利用に関する研究・主任研究者総括報告書 厚生労働科学研究費補助金研究報告書 (2012)
  • Author(s): 細野 眞
• [Book] 医療放射線の安全確保と有効利用に関する研究・主任研究者総括報告書 厚生労働科学研究費補助金研究報告書(平成23年度) (2012)
  • Author(s): 細野 眞
• [Book] 中長期的に展望する医療放射線の安 全規制に関する課題 厚生労働科学研究費補助金研究報告書(平成23年度) (2012)
  • Author(s): 細野 眞、藤村洋子、堀越亜希子、柳田 幸子
• [Book] 切除不能肝癌の治療に用いられるイ ットリウム-90 樹脂微小球体の有効性と投与された患者の管理区域からの退出などの放射線防護対策について 厚生労働科学研究 費補助金研究報告書(平成23年度) (2012)
  • Author(s): 細野 眞、米矢吉宏、宇佐美公男、花岡 宏平、池渕秀治、中村吉秀、中村伸貴、柳田 幸子、山田崇裕、北岡麻美、小島清孝、菅野 宏泰
• [Book] PET-CT、PET-MRI 及びSPECT-CT 検査における放射線の安全確保に関する検討 厚生労働科学研究費補助金研究報告書(平成23年度) (2012)
  • Author(s): 細野 眞、米矢吉宏、宇佐美公男、花岡 宏平、池渕秀治、中村吉秀、中村伸貴、柳田 幸子、山田崇裕、北岡麻美
• [Book] 核医学治療(RI内用療法)における放射線安全の確保に関する検討 厚生労働科学研究費補助金研究報告書(平成23年度) (2012)
  • Author(s): 米矢吉宏、細野 眞、宇佐美公男、花岡 宏平、池渕秀治、中村吉秀、中村伸貴、柳田 幸子、山田崇裕、北岡麻美
• [Book] 厚生労働科学研究費補助金研究報告書(平成23年度) (2012)
  • Author(s): 核医学治療(RI 内用療法)における放射線安全の確保に関する検討
• [Book] 放射性同位元素内用療法162-165 臨床放射線腫瘍学(編集日本放射線腫瘍学会・日本放射線腫瘍学研究機構) (2012)
  • Author(s): 細野 眞
  • Publisher: 南江堂
• [Book] FDG PET PET/CT 診療ガイドライン2012 (2012)
  • Author(s): 細野 眞
  • Publisher: 核医学
• [Book] Gamut of FDG-PET (2012)
  • Author(s): 御前 隆、石津浩一、石守崇好、工藤崇、中本 裕士、東 達也、細野 眞
  • Publisher: 核医学
• [Book] 臨床放射線腫瘍学 (2012)
  • Author(s): 細野 眞
  • Total Pages: 534
  • Publisher: 南江堂
• [Book] 医療放射線の安全確保と有効利用に関する研究・主任研究者総括報告書 厚生労働科学研究費補助金研究報告書(平成22年度) (2011)
  • Author(s): 細野 眞
• [Book] 中長期的に展望する医療放射線の安全規制に関する課題 厚生労働科学研究費補助金研究報告書(平成22年度) (2011)
  • Author(s): 細野 眞 藤村洋子、堀越亜希子
• [Book] PET 第3版今日の消化器疾患 治療指針 (2010)
  • Author(s): 細野 眞
  • Publisher: 医学書院
• [Book] 医療放射線の安全確保に関する研究・主任研究者総括報告書 厚生労働科 学研究費補助金研究報告書(平成21年度) (2010)
  • Author(s): 細野 眞
• [Book] 中長期的に展望する医療放射線の安全規制に関する課題 厚生労働科学研究費 補助金研究報告書(平成21年度) (2010)
  • Author(s): 細野 眞 並木宣雄、藤村洋子、堀越亜 希子
• [Book] エックス線診療線量の測定とその全国実施の手法に関する課題 厚生労働科学研究費補助 金研究報告書(平成21年度) (2010)
  • Author(s): 宇佐美公男、細野 眞、米矢吉宏、白石 美保、松本圭一、池渕秀治、中村吉秀、柳田 幸子、中村伸貴、吉田浩一、福田光道
• [Remarks]
  • URL: http://positron.me
• [Remarks] 医療放射線と未来
  • URL: http://positron.me
• [Remarks]
  • URL: http://kuaeri.ned.kindai.ac.jp/kenkyusho/kenkyushitsu_shokai/hosono.html