Prediction of recurrence in stage I gastric cancer
Project/Area Number |
21591711
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Digestive surgery
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Research Institution | Kitasato University |
Principal Investigator |
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Project Period (FY) |
2009 – 2011
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Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
|
Keywords | 胃癌 / 再発 / Stage I / HOPX / メチル化 / 予後因子 / 患者選択 / HOP / ホメオボックス蛋白 / 定量 / 臨床病理学的因子 |
Research Abstract |
In stage I advanced gastric cancer, HOPX methylation and PRL-3 protein expression were investigated for prediction marker of recurrence. As a result, PRL-3 protein expression is closely correlated with recurrence of stage I advanced gastric cancer, and its validation study is the next step for this purpose.
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Report
(4 results)
Research Products
(23 results)
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[Journal Article] Liver metastasis of colorectal cancer by protein-tyrosine phosphatase type 4A, 3(PRL-3) is mediated through lymph node metastasis and elevated serum tumor markers such as CEA and CA19-92008
Author(s)
Hatate K, Yamashita K, Hirai K, Kumamoto H, Sato T, Ozawa H, Nakamura T, Onozato W, Kokuba Y, Ihara A, Watanabe M.
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Journal Title
Oncol Rep
Volume: 20(4)
Pages: 737-43
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