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The role of autophagy in the differentiation of T cells in the thymic epithelial tumors

Research Project

Project/Area Number 21591813
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Thoracic surgery
Research Institution独立行政法人国立病院機構近畿中央胸部疾患センター(臨床研究センター) (2011)
Clinical Research Center, National Hospital Organization, Kinki-Chuo Chest Medical Center (2010)
Osaka University (2009)

Principal Investigator

UTSUMI Tomoki  独立行政法人国立病院機構近畿中央胸部疾患センター(臨床研究センター), 呼吸器外科, 医長 (40423165)

Co-Investigator(Kenkyū-buntansha) OKUMURA Meinoshin  大阪大学, 医学系研究科, 教授 (40252647)
MINAMI Masato  大阪大学, 医学部附属病院, 准教授 (10240847)
SAWABATA Noriyoshi  大阪大学, 医学系研究科, 准教授 (50403184)
INOUE Masayoshi  大阪大学, 医学系研究科, 講師 (10379232)
KADOTA Yoshihisa  大阪大学, 医学系研究科, 助教 (50464243)
SHIGEMURA Norihisa  大阪大学, 医学系研究科, 助教 (30505508)
TOKUNAGA Toshiteru  大阪大学, 医学部・附属病院, 医員 (70448059)
IDEGUCHI Kan  大阪大学, 医学部・附属病院, 医員 (60448058)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords縦隔外科学 / 胸腺腫 / T細胞 / オートファジー / Atg5 / Beclin1 / LC3 / Beclin 1
Research Abstract

Thymoma tissues were accumulated from the surgical specimens to investigate phenotype of lymphocyte markers, expression of autophagy-related genes and histological cell types. There were no apparent relationships between 3 studied autophagy-related genes and clinical characteristics of thymomas, lymphocyte phenotypes, and histological cell types.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

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