Functional analysis of prostate cancer spheroid forming related genes and its clinical application
| Project/Area Number |
21592034
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Urology
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| Research Institution | Yokohama National University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
SHIRAISHI Taizo 三重大学, 医学系研究科, 教授 (30162762)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 前立腺癌 / スフェロイド / siRNA / 前立腺がん |
|---|
| Research Abstract |
Some genes including the Plk2were extracted as a candidate gene related with spheroid formation. We analyzed effects of the Plk2on the spheroid characterization and anticancer drug resistance in DU-145 spheroids by suppressing plk2with RNAi. The results indicate that the Plk2may be involved in suppression of tumor growth and acquisition of anticancer drug resistance.
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Report
(4 results)
Research Products
(36 results)
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[Presentation] 腫瘍と腫瘍微小環境2011
Author(s)
渡邉昌俊
Organizer
化学工学会第43回秋季大会シンポジウム
Place of Presentation
名古屋工業大学,名古屋
Year and Date
2011-09-15
Related Report
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[Presentation] 腫瘍と腫瘍微小環境2011
Author(s)
渡邉昌俊
Organizer
化学工学会第43回秋季大会シンポジウム
Place of Presentation
名古屋工業大学、名古屋
Year and Date
2011-09-15
Related Report
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[Presentation] 前立腺癌スフェロイドの解析2009
Author(s)
森田城次, 上大介, 米田操, 広川佳史, 白石泰三, 渡邉昌俊
Organizer
第68回日本癌学会学術総会
Place of Presentation
パシフィコ横浜
Year and Date
2009-10-02
Related Report
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