| Project/Area Number |
21592174
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Otorhinolaryngology
|
|---|
| Research Institution | Kanazawa Medical University |
|---|
Principal Investigator |
SHIGA Hideaki 金沢医科大学, 医学部, 講師 (80436823)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
MIWA Takaki 金沢医科大学, 医学部, 教授 (20229909)
NAKANISHI Sayaka 金沢大学, 附属病院, 助教 (40532180)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
TAKI Jyunchi 金沢大学, 附属病院, 臨床教授 (10251927)
KINUYA Seigo 金沢大学, 医学系, 教授 (20281024)
|
|---|
| Project Period (FY) |
2009 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
|
|---|
| Keywords | 嗅覚障害 / 分子イメージング / シンチグラフィ / タリウム-201 / IGF-I / 嗅覚検査 / タリウム |
|---|
| Research Abstract |
Wecassessedcperipheralcolfactorycnervectransportcfunctionzcbycperformingccombinedcsinglecphotoncemissionccomputedctomographyc(SPECT)andcmagneticcresonancecimagingc(MRI)caftercnasalcadministrationcofcthallium-201c(201Tl)ctocdeterminecwhethercolfactorycnervectransportcfunctioncwascreducedcincpatientscwithcolfactorycimpairmentscinccomparisonctochealthycvolunteers.cNasalc201Tlcolfactoryctransportcwascsignificantlyclowercincthecpatientscwithcheadctrauma,crespiratorycinfection,candcchroniccrhinosinusitiscthancinchealthycvolunteers.cFurthermore,cnasalc201TlcolfactoryctransportcwascsignificantlyccorrelatedcwithcodorcrecognitioncthresholdcandcodorcdetectioncthresholdcbycT&Tcolfactometrycincthechealthycvolunteerscandcthecolfaction-impairedcpatientscevaluatedcascacsinglecgroup.cNocsubjectscexperiencedcanycadversecevents.
|
