| Project/Area Number |
21592179
|
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Otorhinolaryngology
|
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| Research Institution | Kyorin University (2011)
Juntendo University (2009-2010) |
|---|
Principal Investigator |
|
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| Co-Investigator(Kenkyū-buntansha) |
YOSHITAKE Hiroshi 順天堂大学, 医学部, 助教 (00396574)
高森 建二 順天堂大学, 医学部, 特任教授 (40053144)
池田 勝久 順天堂大学, 医学部, 教授 (70159614)
冨永 光俊 順天堂大学, 大学院・医学研究科, 研究員 (50468592)
|
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| Project Period (FY) |
2009 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
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| Keywords | 神経反発因子 / セマフォリ3A / アレルギー性鼻炎 / 鼻粘膜過敏症 / 鼻アレルギー / 神経反発因子Sema3A / Semaphorin 3A / neuropilin-1 / VEGFR-1,2 |
|---|
| Research Abstract |
Semaphorin 3A(Sema3A), a nerve repulsion factor, has been reported to be specifically associated with a role in chronic inflammation of the nerves(i. e., in cases of nasal mucosal hypersensitivity), but not in allergic inflammation in the human nasal mucosa.
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