| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Research Abstract |
A germ cell-marker glycoprotein, TEX101 is expressed not only in germ cells but also in cancer cells from patients with head and neck squamous cell carcinoma, demonstrating that this molecule is a novel cancer/testis antigen. The rate of lymph nodes metastasis tends to be low in the TEX101-positive HNSCC patients, compared to the patients with cancer of weak positive and negative expression of TEX101. TEX101 may be useful as a biological marker and a target for cancer therapy.
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