Cytokine profile in biliary atresia patients
| Project/Area Number |
21592273
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Pediatric surgery
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| Research Institution | Chiba University |
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Principal Investigator |
SAITO Takeshi 千葉大学, 医学部・附属病院, 講師 (20406044)
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| Co-Investigator(Kenkyū-buntansha) |
YOSHIDA Hideo 千葉大学, 大学院・医学研究院, 教授 (60210712)
HISHIKI Tomoro 千葉大学, 大学院・医学研究院, 講師 (00375776)
MITUNAGA Tetsuya 千葉大学, 医学部附属病院, 助教 (80375774)
NAKATA Mituyuki 千葉大学, 医学部附属病院, 助教 (90375775)
SATO Yoshiharu 千葉大学, 医学部附属病院, 助教 (60375772)
TERUI Keita 千葉大学, 医学部附属病院, 助教 (70375773)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 先天性消化器疾患学 / 胆道閉鎖症 / サイトカイン / サイトカインネットワーク / 自然免疫 / フローサイトメトリー |
|---|
| Research Abstract |
Using the serum and liver specimens taken from biliary atresia (BA)patients around the operation, we investigated both the systemic and local immunological environment of BA. It was suggested the significant difference between Th1 and Th2 cytokines expression levels has not been found in the systemic immunity. However, the representative local environment in the liver showed Th1 polarization.
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Report
(4 results)
Research Products
(24 results)
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[Journal Article] Use of preoperative, 3-dimensional magnetic resonance cholangiopancreatography in pediatric choledochal cysts2011
Author(s)
Saito T, Hishiki T, Terui K, Sato Y, Mitsunaga T, Terui E, Nakata M, Takenouchi A, Matsuura G, Yahata E, Ohno S, Sato H, Yanagawa N, Masuda Y, Yoshida H
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Journal Title
Surgery
Volume: 149
Issue: 6
Pages: 569-75
DOI
Related Report
Peer Reviewed
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[Presentation] 胆道閉鎖症における血中サイトカイン解析の意義2010
Author(s)
齋藤武, 菱木知郎, 照井慶太, 佐藤嘉治, 光永哲也, 松浦玄, 八幡江里子, 三瀬直子, 柴田涼平, 坂本明美, 幡野雅彦, 岩井潤, 東本恭幸, 吉田英生
Organizer
第37回日本胆道閉鎖症研究会
Place of Presentation
東京
Year and Date
2010-12-11
Related Report
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[Presentation] 胆道閉鎖症における血中サイトカイン解析の意義2010
Author(s)
齋藤武, 菱木知郎, 照井慶太, 佐藤嘉治, 武之内史子, 八幡江里子, 大野幸恵, 三瀬直子, 吉田英生, 坂本明美, 幡野雅彦, 岩井潤, 東本恭幸, 光永哲也
Organizer
第47回日本小児外科学会総会
Place of Presentation
名古屋
Year and Date
2010-06-17
Related Report
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