Analysis of vascular endothelial cell differentiation and growth system in the rat tongue inflammation model.
Project/Area Number |
21592348
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Morphological basic dentistry
|
Research Institution | Tsurumi University |
Principal Investigator |
|
Co-Investigator(Kenkyū-buntansha) |
SATO Etsuji 鶴見大学, 歯学部, 教授 (10162447)
|
Project Period (FY) |
2009 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
Keywords | 口腔解剖学(含組織学・発生学) / 舌炎 / LPS / アデノシンレセプター / 抗原提示細胞 |
Research Abstract |
To make the model of tongue inflammation, inject the LPS with incomplete Freund's adjuvant. About 8days after the injection, the luminal areas of blood vessels were increased. But inject antagonists of adenosine receptors before to inject the LPS and incomplete Freund's adjuvant, the ratio of blood vessels in the lingual tissue was remarkably reduced. These results show that adenosine receptors are very important roll of vascular endothelial growth.
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Report
(4 results)
Research Products
(7 results)