| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Research Abstract |
The dental pulp is a microcirculation-rich tissue. The abundant vascular network may influence the process of the tertiary dentin formation. we investigated the effects of the injured endothelial cells on rat cultured dental pulp cells using the Nd : YAG laser irradiation. After 5 days, tgf-β1expression was detected clearly in the laser irradiated RAOEC with pulp cells though the expression was weak without pulp cells. These findings suggest that after laser irradiation, the tgf-β1expression is enhanced rapidly by the migrated pulp cells or the co-culture of both cells. Immunohistochemical examination showed that after 8 days, the AcGFP1 labeled-pulp cells in endothelial cells expressed TGF-β1.
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