Regulation of periodontal tissue re-generation with combination use of FGF-2 and on-demand 3D shaped graft material
| Project/Area Number |
21592495
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Dental engineering/Regenerative dentistry
|
|---|
| Research Institution | Osaka University |
|---|
Principal Investigator |
NOZAKI Takenori 大阪大学, 大学院・歯学研究科, 助教 (30263304)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
KITAMURA Masahiro 大阪大学, 大学院・歯学研究科, 准教授 (10243247)
SAHO Teruyuki 大阪大学, 歯学部附属病院, 助教 (10263295)
|
|---|
| Project Period (FY) |
2009 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
|---|
| Keywords | 組織再生 / シグナル分子 / インプラント / FGF-2 / 再生歯学 / 三次元培養 |
|---|
| Research Abstract |
It is confirmed that the combination use of FGF-2 and beta-TCP has a significant potential to promote periodontal tissue regeneration in an animal model study. Additionally, it is revealed that FGF-2 promotes osteogenesis and initial osseo-integration of implant with low primary stability. These results suggest that FGF-2 is a Signaling molecule suitable for on-demand 3D shaped transplant material which promotes tissue regeneration effectively
|
Report
(4 results)
Research Products
(6 results)
