Salivary glands reproduction and reacquisition of saliva secretion ability on the new Sjogren' s syndrome model mice.

• Project/Area Number: 21592530
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Surgical dentistry
• Research Institution: Kyushu University
• Principal Investigator: OHYAMA Yukiko 九州大学, 歯学研究院, 助教 (70294957)
• Co-Investigator(Kenkyū-buntansha): FUJII Jun 九州大学, 大学院・医学研究院, 准教授 (60271441) ; NAKAMURA Seiji 九州大学, 大学院・歯学研究院, 教授 (60189040)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
• Keywords: シェーグレン症候群 / 唾液腺再生

Research Abstract

We tried to reproduce salivary glands of Sjogren' s syndrome model mice transferring side population cells(SP cells), but we could not do. We established the method to culture embryo salivary glands and confirmed the growth of these cells under the capsule of the kidney. We now observe the change of SP cells co-culturing with embryo tissue.

Research Products

• [Journal Article] Sonographic diagnosis for Mikulicz disease (2009)
  • Author(s): Shimizu M, Moriyama M, Okamura K, Kawazu T, Chikui T, Goto TK, Ohyama Y, Nakamura S, Yoshiura K.
  • Journal Title: Oral Med Oral Pathol Oral Radiol Endod Volume: 108(1) Pages: 105-113
• [Journal Article] Sonographic diagnosis for Mikulicz disease (2009)
  • Author(s): Shimizu M, et al.
  • Journal Title: Oral Surg Oral Med Oral Pathol Oral Radiol Endod 108(1) Pages: 105-113
  • Peer Reviewed