| Project/Area Number |
21592608
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Orthodontic/Pediatric dentistry
|
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| Research Institution | University of Miyazaki (2010-2011)
Kagoshima University (2009) |
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Principal Investigator |
NAGATA Junko 宮崎大学, 医学部, 講師 (50264429)
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| Co-Investigator(Kenkyū-buntansha) |
MIYAWAKI Shoichi 鹿児島大学, 大学院・医歯学総合研究科, 教授 (80295807)
INUI Akio 鹿児島大学, 大学院・医歯学総合研究科, 教授 (80168418)
OHMURE Haruhito 鹿児島大学, 大学院・医歯学総合研究科, 講師 (00404484)
SAKAGUCHI Katuyoshi 鹿児島大学, 医歯学総合研究科, 助教 (80381185)
YAMAMOTO Takafumi 鹿児島大学, 医学部・歯学部附属病院, 講師 (00457649)
SAKODA Sumio 宮崎大学, 医学部, 教授 (20118079)
KASHIMA Koji 宮崎大学, 医学部, 講師 (30233703)
IGAWA Kaori 宮崎大学, 医学部, 助教 (90423722)
YOKOTA Rie 宮崎大学, 医学部, 医員 (10530339)
OGAWA Yasufumi 宮崎大学, 医学部, 医員 (20572720)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Keywords | 睡眠時ブラキシズム / 胃酸 / 微小覚醒 / 睡眠深度 / 自律神経 / ホルモン / 終夜睡眠ポリグラフ検査 / 微少覚醒 / 心拍変動 / 周波数解析 / 咬筋活動 / 胃食道逆流 / 睡眠ポリグラフ検査 / 咬筋筋電図 / 歯ぎしり / GERD / 食道内pH / RMMA / 食道内酸刺激 |
|---|
| Research Abstract |
The purpose of this study is experimental induction or reduction of the sleep bruxism(SB). The frequencies of SB episodes were significantly induced after intra esophageal infusion with 5 ml acidic solution in healthy adults. Then, polysomnogram, the frequency analysis of heart rate variability and blood hormone level were examined in SB patients and healthy subjects. Most SB episodes were observed under a sympathetic dominance at light non-REM sleep with the micro-arousals. The SB patients showed low quality of sleep at sympathetic predominance and high level of stress related hormone. Also, it was suggested that the SB episodes were significantly reduced through central nerve by a medication.
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