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Follow-up Study on Oral and Systemic Health in Elderly

Research Project

Project/Area Number 21592644
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Social dentistry
Research InstitutionNiigata University

Principal Investigator

MIYAZAKI Hideo  新潟大学, 医歯学系, 教授 (00157629)

Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywordsコホート研究 / 高齢者 / 口腔と全身 / 栄養 / 死亡リスク
Research Abstract

Elderly subjects surveyed between 1998 and 2008 were followed-up for 3 years from 2009 to 2011. Each subject or his/her family, if necessary, was interviewed about a medical history including cause of death, and received oral health and physical fitness examinations once a year. The results suggested that 1) bone metabolic markers influenced periodontal disease progression and decrease of bone mineral density, and also influenced mandibular inferior cortex related to bone stiffness and tooth loss, 2) a low total cholesterol serum level, low docosahexaenoic acid intake and dietary saturated fatty acids, respectively, influenced to periodontal disease progression, 3) non-smoking elderlies with root caries were at an elevated risk for dysrhythmias, and 4) low estimated glomerular filtration rate was a risk for cardiovascular disease occurrence and also for mortality.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (58 results)

All 2012 2011 2010 2009 Other

All Journal Article (31 results) (of which Peer Reviewed: 31 results) Presentation (21 results) Book (2 results) Remarks (4 results)

  • [Journal Article] Serum albumin(SA) levels and 10-year mortality in a community-dwelling 70-year-old population2012

    • Author(s)
      Y. Takata, T. Ansai, A. Yoshihara and H. Miyazaki
    • Journal Title

      Arch. Gerontol. Geriatr.

      Volume: 54 Pages: 39-43

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Serum albumin (SA) levels and 10-year mortality in a community-dwelling 70-year-old population2012

    • Author(s)
      Y.Takata, H.Miyazaki, et al.
    • Journal Title

      Arch.Gerontol.Geriatr.

      Volume: 54 Pages: 39-43

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Periodontal disease and decreased kidney function in Japanese elderly2012

    • Author(s)
      M.Iwasaki, H.Miyazaki, et al.
    • Journal Title

      Amer.J.Kidney Dis.

      Volume: 59 Pages: 202-209

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Relations of serum ascorbic acid and α-tocopherol to periodontal disease2012

    • Author(s)
      M.Iwasaki, H.Miyazaki, et al.
    • Journal Title

      J.Dent.Res.

      Volume: 91 Pages: 167-172

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association of dental status with vegetable intake in an elderly population2012

    • Author(s)
      T.Hirotomi, H.Miyazaki, et al.
    • Journal Title

      J.Aging Res.Clin.Prac.

      Volume: 1 Pages: 84-87

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Tooth-related risk factors for tooth loss in community-dwellingel derly people2012

    • Author(s)
      T.Hirotomi, H.Miyazaki, et al.
    • Journal Title

      Community Dent.Oral Epidemiol.

      Volume: 40 Issue: 2 Pages: 154-163

    • DOI

      10.1111/j.1600-0528.2011.00648.x

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Longitudinal relationship between root caries and arrhythmias in elderly populations2011

    • Author(s)
      M. Kaneko, A. Yoshihara and H. Miyazaki
    • Journal Title

      Gerodontology

      Volume: 28 Pages: 289-295

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Glomerular filtration rate and 10-year mortality in a 70-year-old community-dwelling Japanese population2011

    • Author(s)
      Y. Takata, T. Ansai, A. Yoshihara and H. Miyazaki
    • Journal Title

      Aging Clin. Exp. Res.

      Volume: 23 Pages: 223-230

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Relationship between bone fragility of the mandibular inferior cortex and tooth loss related to periodontal disease in older people2011

    • Author(s)
      A. Yoshihara, T. Deguchi and H. Miyazaki
    • Journal Title

      Community Dental Health

      Volume: 28 Pages: 165-169

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Relationship among bone turnover, renal function and periodontal disease in elderly Japanese2011

    • Author(s)
      A. Yoshihara, Y. Hayashi and H. Miyazaki
    • Journal Title

      J. Periodont. Res.

      Volume: 46 Pages: 491-496

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Relationship between saturated fatty acids and periodontal disease2011

    • Author(s)
      M. Iwasaki, M. C. Manz, P. Moynihan, A. Yoshihara, K. Muramatsu, R. Watanabe and H. Miyazaki
    • Journal Title

      J. Dent. Res.

      Volume: 90 Pages: 861-867

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Relationships between the amount of saliva and medications in elderly individuals2011

    • Author(s)
      K. Ichikawa, S. Sakuma, A. Yoshihara, H. Miyazaki, S. Funayama, K. Ito and A. Igarashi
    • Journal Title

      Gerodontology

      Volume: 28 Pages: 116-120

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Influence of dental occlusion on physical fitness decline in a healthy Japanese elderly population2011

    • Author(s)
      N. Okuyama, T. Yamaga, A. Yoshihara, K. Nohno, Y. Yoshitake, Y. Kimura, M. Shimada, N. Nakagawa, M. Nishimuta, M. Ohashi and H. Miyazaki
    • Journal Title

      Arch. Gerontol. Geriatr.

      Volume: 2 Pages: 172-176

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Dietary ratio of n-6 to n-3 polyunsaturated fatty acids and periodontal disease in community-based older Japanese : a 3-year follow up study2011

    • Author(s)
      M.Iwasaki, H.Miyazaki, et al.
    • Journal Title

      Prostaglandins Leukot Essent Fatty Acids

      Volume: 85 Pages: 107-112

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Relationship between saturated fatty acids and periodontal disease2011

    • Author(s)
      M.Iwasaki, H.Miyazaki, et al.
    • Journal Title

      J.Dent.Res.

      Volume: 90 Pages: 861-867

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Relationship among bone turnover, renal function and periodontal disease in elderly Japanese2011

    • Author(s)
      A.Yoshihara, et al
    • Journal Title

      Journal of Periodontal Research

      Volume: 46 Issue: 4 Pages: 491-496

    • DOI

      10.1111/j.1600-0765.2011.01365.x

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Glomerular filtration rate and 10-year mortality in a 70-year-old community-dwelling Japanese population2011

    • Author(s)
      Y.Takata, H.Miyazaki, et al.
    • Journal Title

      Aging Clin.Exp.Res.

      Volume: 23 Pages: 223-230

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mineral content of calcium and magnesium in the serum and longitudinal periodontal progression in Japanese elderly smokers2011

    • Author(s)
      A.Yoshihara, H.Miyazaki, et al.
    • Journal Title

      J.Clin.Periodontol.

      Volume: 38 Issue: 11 Pages: 992-997

    • DOI

      10.1111/j.1600-051x.2011.01769.x

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Longitudinal relationship between dietary omega-3 fatty acids and periodontal disease2010

    • Author(s)
      M. Iwasaki, A. Yoshihara, P. Moynihan, R. Watanabe, G. W. Taylor and H. Miyazaki
    • Journal Title

      Nutrition

      Volume: 26 Pages: 1105-1109

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Tooth-related risk factors for periodontal disease in community-dwelling elderly people2010

    • Author(s)
      T. Hirotomi, A. Yoshihara, H. Ogawa and H. Miyazaki
    • Journal Title

      J. Clin. Periodontol.

      Volume: 37 Pages: 494-500

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Relationship between mandibular inferior cortex and bone stiffness in Japanese elderly people2010

    • Author(s)
      B. Kiswanjaya, A. Yoshihara, T. Deguchi-Saito and H. Miyazaki
    • Journal Title

      Osteoporos. Int.

      Volume: 21 Pages: 433-438

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Relationship between mandibular inferior cortex and bone stiffness in Japanese elderly people.2010

    • Author(s)
      B.Kiswanjaya, H.Miyazaki, et al.
    • Journal Title

      Osteoporos.Int.

      Volume: VOL.21 Pages: 433-438

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Tooth-related risk factors for periodontal disease in community-dwelling elderly people.2010

    • Author(s)
      T.Hirotomi, H.Miyazaki, et al.
    • Journal Title

      J.Clin.Periodontol.

      Volume: VOL.37 Pages: 494-500

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Longitudinal relationship between dietary omega-3 fatty acids andperiodontal disease.2010

    • Author(s)
      M.Iwasaki, H.Miyazaki, et al.
    • Journal Title

      Nutrition

      Volume: VOL.26 Pages: 1105-1109

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Physical function is weakly associated with angiotensin-converting enzyme gene I/D polymorphism in elderly Japanese subjects2009

    • Author(s)
      A. Yoshihara, T. Tobina, T. Yamaga, M. Ayabe, Y. Yoshitake, Y. Kimura, M. Shimada, M. Nishimuta, N. Nakagawa, M. Ohashi, N. Hanada, H. Tanaka, A. Kiyonaga and H. Miyazaki
    • Journal Title

      Gerontology

      Volume: 55 Pages: 387-392

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] A longitudinal study of the relationship between diet intake and dental caries and periodontal disease in elderly Japanese subjects2009

    • Author(s)
      A. Yoshihara, R. Watanabe, N. Hanada and H. Miyazaki
    • Journal Title

      Gerodontology

      Volume: 26 Pages: 130-136

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] The relationship between serum lipids and periodontitis in elderly non-smokers2009

    • Author(s)
      A. Izumi, A. Yoshihara, T. Hirotomi and H. Miyazaki
    • Journal Title

      J. Periodontol.

      Volume: 80 Pages: 740-748

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Relation of bone turnover markers to periodontal disease and jaw bone morphology in elderly Japanese subjects2009

    • Author(s)
      A. Izumi, A. Yoshihara, T. Hirotomi and H. Miyazaki
    • Journal Title

      Oral Dis.

      Volume: 15 Pages: 176-181

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Relation of bone turnover markers to periodontal disease and jaw bone morphology in elderly Japanese subjects2009

    • Author(s)
      A.Yoshihara, H.Miyazaki, et al.
    • Journal Title

      Oral Dis. 15

      Pages: 176-181

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The relationship between serum lipids and periodontitis in elderly non-smokers2009

    • Author(s)
      A.Izumi, H.Miyazaki, et al.
    • Journal Title

      J.Periodontol. 80

      Pages: 740-748

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A longitudinal study of the relationship between diet intake and dental caries and periodontal disease in elderly Japanese subjects2009

    • Author(s)
      A.Yoshihara, H.Miyazaki, et al.
    • Journal Title

      Gerodontology 26

      Pages: 130-136

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] Few Remaining Teeth is Associated with High Systolic and Diastolic Blood Pressure in Elderly People2011

    • Author(s)
      Hirotomi T, Yoshihara A, Miyazaki H
    • Organizer
      第60回日本口腔衛生学会・総会
    • Place of Presentation
      松戸市
    • Related Report
      2011 Final Research Report
  • [Presentation] Relationship between Autoantibody Associated with Rheumatoid Arthritis and Tooth Loss2011

    • Author(s)
      Hayashi Y, Yoshihara A, Miyazaki H
    • Organizer
      第60回日本口腔衛生学会・総会
    • Place of Presentation
      松戸市
    • Related Report
      2011 Final Research Report
  • [Presentation] Dietary Antioxidant Intake and Periodontal Disease in Community-based Older Japanese2011

    • Author(s)
      Iwasaki M, Yoshihara A, Miyazaki H
    • Organizer
      第60回日本口腔衛生学会・総会
    • Place of Presentation
      松戸市
    • Related Report
      2011 Final Research Report
  • [Presentation] The Niigata Elderly Study and Lessons2011

    • Author(s)
      H.Miyazaki
    • Organizer
      The Workshop on Improving the Oral Health of Older Australians
    • Place of Presentation
      シドニー(オーストラリア)コンコルド病院(招待講演)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Dietary ratio ofω-6 toω-3 polyunsaturated fatty acids and periodontal disease in a community-based older Japanese : a 3-year follow-up study2010

    • Author(s)
      Iwasaki M, Taylor GW, Yoshihara A, Muramatsu K, Watanabe R, Miyazaki H
    • Organizer
      University of Michigan School of Dentistry Research Day
    • Year and Date
      2010-02-09
    • Related Report
      2011 Final Research Report
  • [Presentation] Effect of n-6 to n-3 polyunsaturated fatty acids ratio on periodontal health : 3-year follow up study2010

    • Author(s)
      Iwasaki M, Taylor GW, Moynihan P, Yoshihara A, Muramatsu K, Watanabe R, Miyazaki H
    • Organizer
      第58回国際歯科研究学会日本部会(JADR)総会・学術大会
    • Place of Presentation
      北九州市
    • Related Report
      2011 Final Research Report
  • [Presentation] Association of edentulism and vegetable intake in community-dwelling older adults2010

    • Author(s)
      Hirotomi T, Yoshihara A, Miyazaki H
    • Organizer
      9th International Conference of Asian Academy of Preventive Dentistry
    • Place of Presentation
      Kuala Lumpur(Malaysia)
    • Related Report
      2011 Final Research Report
  • [Presentation] Periodontal disease may affect kidney function in a community-based Japanese older population2010

    • Author(s)
      Iwasaki M, Yoshihara A, Miyazaki H
    • Organizer
      第59回日本口腔衛生学会総会
    • Place of Presentation
      新潟市
    • Related Report
      2011 Final Research Report
  • [Presentation] Relation of bone turnover markers to periodontal disease in elderly2010

    • Author(s)
      Yoshihara A, Hayashi Y, Miyazaki H
    • Organizer
      88th General Session of the IADR
    • Place of Presentation
      Barcelona(Spain)
    • Related Report
      2011 Final Research Report
  • [Presentation] Low body fatness is related to bone fragility in elderly2010

    • Author(s)
      Kiswanjaya B, Yoshihara A, Miyazaki H
    • Organizer
      88th General Session of the IADR
    • Place of Presentation
      Barcelona(Spain)
    • Related Report
      2011 Final Research Report
  • [Presentation] Systemic health-the dentists role2010

    • Author(s)
      Miyazaki H
    • Organizer
      Satellite symposium on Geriatric Oral Health Research
    • Place of Presentation
      Barcelona(Spain)
    • Related Report
      2011 Final Research Report
  • [Presentation] Systemic health-the dentists role.2010

    • Author(s)
      H.Miyazaki
    • Organizer
      Satellite Symposium on Geriatric Oral Health Research
    • Place of Presentation
      バルセロナ(スペイン)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Physical fitness and nine-year mortality in 70-year-old population2009

    • Author(s)
      Shimada M, Yoshitake Y, Kimura Y, Nakagawa N, Nagayama H, Nishimuta M, Ohashi M, Miyazaki H
    • Organizer
      American College of Sports and Med
    • Year and Date
      2009-05-29
    • Related Report
      2011 Final Research Report
  • [Presentation] Health Promotion and Oral Health-Japanese Experience-2009

    • Author(s)
      H. Miyazaki
    • Organizer
      7th Global Conference Health Promotion
    • Place of Presentation
      Nairobi(Kenya)
    • Related Report
      2011 Final Research Report
  • [Presentation] Periodontal disease progression over 10 years in an elderly population2009

    • Author(s)
      Hirotomi T, Yoshihara A, Miyazaki H
    • Organizer
      9th World Congress on Preventive Dentistry
    • Place of Presentation
      Phuket(Thailand)
    • Related Report
      2011 Final Research Report
  • [Presentation] Volatile sulfur compounds(VSC) may be a risk predictor for periodontal disease progression2009

    • Author(s)
      Makino Y, Yamaga T, Yoshihara A, Nohno K, Miyazaki H
    • Organizer
      International Conference on Breath and Breath Odor Research
    • Place of Presentation
      Dortmund(Germany)
    • Related Report
      2011 Final Research Report
  • [Presentation] Bone turnover markers to periodontal disease and jaw bone morphology2009

    • Author(s)
      Yoshihara A, Deguchi T, Hanada N, Miyazaki H
    • Organizer
      87th General Session of the IADR
    • Place of Presentation
      Miami(USA)
    • Related Report
      2011 Final Research Report
  • [Presentation] Longitudinal relationship between root caries and arrhythmia in elderly populations2009

    • Author(s)
      Kaneko M, Yoshihara A, Miyazaki H
    • Organizer
      87th General Session of the IADR
    • Place of Presentation
      Miami(USA)
    • Related Report
      2011 Final Research Report
  • [Presentation] Longitudinal relationship between dietary docosahexaenoic acid and the dental condition2009

    • Author(s)
      Iwasaki M, Yoshihara A, Maynihan P, Watanabe R, Miyazaki H
    • Organizer
      87th General Session of the IADR
    • Place of Presentation
      Miami(USA)
    • Related Report
      2011 Final Research Report
  • [Presentation] Dental occlusal destruction affects deterioration of physical fitness in elderly2009

    • Author(s)
      Okuyama N, Yamaga T, Yoshihara A, Nohno K, Miyazaki H
    • Organizer
      87th General Session of the IADR
    • Place of Presentation
      Miami(USA)
    • Related Report
      2011 Final Research Report
  • [Presentation] Health Promotion and Oral Health -Japanese Experience-2009

    • Author(s)
      H.Miyazaki
    • Organizer
      7th Global Conference on Health Promotion
    • Place of Presentation
      ナイロビ(ケニヤ)
    • Related Report
      2009 Annual Research Report
  • [Book] 歯の数・口腔機能と健康,健康寿命を延ばす歯科保健医療,歯科医学的根拠とかかりつけ歯科医2009

    • Author(s)
      葭原明弘,宮崎秀夫,日本歯科総合研究機構
    • Publisher
      医歯薬
    • Related Report
      2011 Final Research Report
  • [Book] 健康寿命を延ばす歯科保健医療2009

    • Author(s)
      葭原明弘・宮崎秀夫
    • Total Pages
      182
    • Publisher
      医歯薬出版
    • Related Report
      2009 Annual Research Report
  • [Remarks]

    • URL

      http://www.dent.niigata-u.ac.jp/prevent/japanese/index.html

    • Related Report
      2011 Final Research Report
  • [Remarks]

    • URL

      http://www.dent.niigata-u.ac.jp/prevent/japanese/niigata_study.html

    • Related Report
      2011 Annual Research Report
  • [Remarks]

    • URL

      http://www.dent.niigata-u.ac.jp/prevent/Japanese/niigata_study.html

    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://www.dent.niigata-u.ac.jp/prevent/japanese/niigata_study.html

    • Related Report
      2009 Annual Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

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