Structures and Functions of Bioactive Compounds against Fish Disease

• Project/Area Number: 21603010
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Chemical biology
• Research Institution: Ehime University
• Principal Investigator: KURAMOTO Makoto 愛媛大学, 総合科学研究支援センター, 准教授 (50291505)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000); Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2009: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
• Keywords: 物活性物質 / レンサ球菌症 / 生体機能分子 / 構造解析 / 防御物質 / レンサ球菌

Research Abstract

Aquaculture of flounder is an important industry in Ehime prefecture. However, occurrence of new streptococcal disease and the incidence of resistant bacteria has become a major problem in recent years. We found that there is a repellent effect between Streptococcus iniae and S. parauberis. Therefore, separation of aversive substances has been done. Furthermore, antimicrobial substances(halogenated alkaloids) were isolated from the marine sponge.

Research Products

• [Journal Article] Degradation of methylene blue by radio frequency plasmas in water under ultraviolet irradiation (2010)
  • Author(s): T.Maehara, S.Mukasa, H.Toyota, M.Kuramoto, S.Nomura, A.Kawashima, K.Nishiyama, S.Ohnishi.
  • Journal Title: Journal of Hazardous Materials Volume: 147 Pages: 473-476
  • Peer Reviewed
• [Journal Article] Stellettazole D, a Cytotoxic Imidazole Alkaloid from the Marine Sponge Jaspis duoaster (2010)
  • Author(s): S.Sato, M.Kuramoto, H.Uno, F.Iwata, J.Takeo, H.Kawahara
  • Journal Title: Chemistry Letters Volume: 40 Pages: 186-187
  • NAID: 10027814925
  • Peer Reviewed
• [Journal Article] Tryptophan dimer produced by water-stressed bahia grass is an attractant for Gipaspora margarita and Glomus caledonium (2009)
  • Author(s): Sachie Horii, Makoto Kuramoto, Atsushi Matsumura, Takaaki Ishii
  • Journal Title: World Journal of Microbiology and Biotechnology 25 Pages: 1205-1215
  • Peer Reviewed
• [Journal Article] Effect of the Temperature of Water on the Degradation of Methylene Blue by the Generation of Radio Frequency Plasma in Water (2009)
  • Author(s): Tsunehiro Maehara, Shinobu Mukasa, Hiromichi Toyota, Makoto Kuramoto, Shinfuku Nomura, Ayato Kawashima, Ippei Miyamto, Hiroshi Miyaoka, Shingo Phnishi
  • Journal Title: Journal of Plasma and Fusion Research Series 8 Pages: 627-631
  • Peer Reviewed
• [Presentation] カンキツ果皮に含まれる蛍光物質に関する研究 (2012)
  • Author(s): 倉本誠, 中平祐也, 近藤直, 小川雄一, 山本一哉, MOMIN, MD. Abdul, 井戸恭平
  • Organizer: 日本化学会第92春季年会
  • Place of Presentation: 慶應義塾大学(横浜市)
• [Presentation] 2種の連鎖球菌の拮抗作用からみたヒラメ連鎖球菌症の抑制 (2011)
  • Author(s): 内村祐之, 倉本誠
  • Organizer: 平成23年度瀬戸内・四国ブロック魚病検討会
  • Place of Presentation: 愛媛県南予地方局(宇和島市)
  • Year and Date: 2011-10-04
• [Presentation] 愛媛県産海綿動物由来の含窒素化合物の探索 (2011)
  • Author(s): 横尾義貴, 倉本誠, 宇野英満
  • Organizer: 日本化学会 第91春期年会
  • Place of Presentation: 神奈川大学
  • Year and Date: 2011-03-26
• [Presentation] 2種のレンサ球菌の拮抗阿庄から見たヒラメレンサ球菌症の抑制 (2011)
  • Author(s): 内村祐之, 倉本誠
  • Organizer: 平成23年度瀬戸内・四国ブロック魚病検討会
  • Place of Presentation: 愛媛県南予地方局(宇和島市)
• [Presentation] 愛媛県産海綿動物由来の含窒素化合物の探索 (2011)
  • Author(s): 横尾義貴, 倉本誠, 宇野英満
  • Organizer: 日本化学会第91春季年会
  • Place of Presentation: 神奈川大学(横浜市)
• [Presentation] Study on excitation and fluorescence spectrums of various citrus fruits (2010)
  • Author(s): MD.Momin, N.Kondo, M.Kuramoto, Y.Ogawa, T.Shigi, M.Kurita, K.Ninomiya
  • Organizer: 農業機械学会 開催支部第124回例会
  • Place of Presentation: 岡山大学
  • Year and Date: 2010-08-31
• [Presentation] 愛媛県産海洋生物虜来の生物活性物質 (2010)
  • Author(s): 倉本誠, 横尾義貴, 三宅教道, 宇野英満
  • Organizer: 日本化学会 第90春期年会
  • Place of Presentation: 近畿大学
  • Year and Date: 2010-03-28
• [Presentation] Isolation and elucidation of bioactive compounds from Sada Cape (2010)
  • Author(s): Makoto KURAMOTO, Yoshitaka YOKOO, Norimichi MIYAKE, Hidemitsu UNO
  • Organizer: Pachifichem 2010
  • Place of Presentation: Hawaii
• [Presentation] 愛媛県産海洋生物由来の生物活性物質 (2010)
  • Author(s): 横尾義貴, 三宅教道, 二宮高裕, 倉本誠, 宇野英満
  • Organizer: 日本化学会第90春季年会
  • Place of Presentation: 近畿大学(東大阪市)
• [Presentation] 共生微生物由来の生物活性物質の探索 (2009)
  • Author(s): 横尾義貴, 中島準紀, 佐藤誠造, 倉本誠, 宇野英満
  • Organizer: 日本化学会 西日本大会 2009
  • Place of Presentation: 愛媛大学
  • Year and Date: 2009-11-07
• [Presentation] 共生微生物曲来の生物活性物質の探索 (2009)
  • Author(s): 横尾義貴, 佐藤誠造, 倉本誠, 宇野英満
  • Organizer: 第25回 若手化学者のための化学道場
  • Place of Presentation: 松山市
  • Year and Date: 2009-09-07