high-speed evaluation of microcrystals using X-ray HARP detector

• Project/Area Number: 21604015
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Quantum beam science
• Research Institution: High Energy Accelerator Research Organization
• Principal Investigator: MATSUGAKI Naohiro 大学共同利用機関法人高エネルギー加速器研究機構, 物質構造科学研究所, 助教 (50342598)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000); Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
• Keywords: X線HARP検出器 / タンパク質結晶 / スクリーニング / マイクロビーム / 自動化

Research Abstract

A system was developed to scan protein microcrystals by X-ray beam and to evaluate the diffraction images simultaneously. The system allows rapidly identifying the position and shape of the crystals in tens of micrometers. Automated macromolecular diffraction experiments would be possible by applying this system.