Analysis of elements in enamel of deciduous teeth as a biomarker for fetal environment

• Project/Area Number: 21610002
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Children studies (Studies of environment on children)
• Research Institution: Tohoku University
• Principal Investigator: IGARI Kazuko 東北大学, 病院, 講師 (90125493)
• Co-Investigator(Kenkyū-buntansha): TAKAHASHI Atsushi 東北大学, 病院, 助教 (50333828) ; ANDO Hitomi 東北大学, 歯学研究科, 非常勤講師 (60547272)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000); Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
• Keywords: 胎内環境 / 乳歯 / 元素分析 / 新産線 / 乳歯エナメル質 / マイクロPIXE法

Research Abstract

Trace elements in enamel of deciduous teeth were investigated in order to assess the fatal environment. Deciduous teeth include both pre-natal formed enamel and post-natal formed enamel. They are distinguished by neonatal line. We established the analytical method using micro-PIXE, by which trace elements including pre-and post-natal enamel are measured without destruction of their structure. Some trace elements, Na, Mg, Zn, Sr, and Fe were in prenatal enamel with various concentrations.

Research Products

• [Journal Article] Application of micro-PIXE analysis to investigate trace elements in deciduous teeth enamel (2010)
  • Author(s): K. IGARI, A. TAKAHASHI, H. ANDO, K. ISHII, S. MATSUYAMA, Y. KAWAMURA, S. OHKURA, Y. HASHIMOTO, M. FUJIKAWA, Y. ITOU, K. FUJIKI, Y. HATORI, N. HAMADA, andY. YAMAZAKI
  • Journal Title: Int J PIXE Volume: 20 Pages: 52-56
  • Peer Reviewed
• [Journal Article] Application of micro-PIXE analysis to investigate trace elements in deciduous teeth enamel (2010)
  • Author(s): IGARI K., TAKAHASHI A., ANDO H., et.al
  • Journal Title: International Journal of PIXE Volume: 20 Pages: 51-56
  • Peer Reviewed
• [Presentation] 乳歯エナメル質の新産線前後における元素分布の比較-マイクロPIXE法による検討- (2012)
  • Author(s): 猪狩和子、高橋温、安藤瞳, 他
  • Organizer: 第27回PIXEシンポジウム
  • Place of Presentation: 京都
  • Year and Date: 2012-11-19
• [Presentation] Analysis of trace elements in pre-and post-natal tooth enamel using micro-PIXE (2011)
  • Author(s): K.IGARI, A.TAKAHASHI, H.ANDO, K.ISHII, et.al
  • Organizer: 7^<th> International Symposium on bio-PIXE
  • Place of Presentation: Japan, Sendai
  • Year and Date: 2011-11-01
• [Presentation] Analysis of trace elements in pre-and post-natal tooth enamel using micro-PIXE (2011)
  • Author(s): K. IGARI, A. TAKAHASHI
  • Organizer: The 7th International Symposium for PIXE
  • Place of Presentation: Sendai
• [Presentation] 乳歯エナメル質の新産線前後における元素分布の比較-マイクロPIXE法による検討- (2010)
  • Author(s): 猪狩和子、高橋温、安藤瞳, 他
  • Organizer: 第27回PIXEシンポジウム
  • Place of Presentation: 京都大学宇治キャンパス
  • Year and Date: 2010-11-19
• [Presentation] マイクロPIXE法による乳歯エナメル質の元素分析 (2009)
  • Author(s): 高橋温、猪狩和子、安藤瞳, 他
  • Organizer: 第26回PIXEシンポジウム
  • Place of Presentation: 千葉
  • Year and Date: 2009-11-18