| Project/Area Number |
21659475
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Orthodontic/Pediatric dentistry
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| Research Institution | Hiroshima University |
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Principal Investigator |
KOZAI Katsuyuki 広島大学, 大学院・医歯薬学総合研究科, 教授 (10178212)
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| Co-Investigator(Kenkyū-buntansha) |
SUZUKI Junji 広島大学, 大学院・医歯薬学総合研究科, 准教授 (90263714)
MITSUHATA Chieko 広島大学, 大学院・医歯薬学総合研究科, 助教 (10335664)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,270,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,100,000 (Direct Cost: ¥1,100,000)
Fiscal Year 2009: ¥1,000,000 (Direct Cost: ¥1,000,000)
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| Keywords | 小児糖尿病 / 口腔バイオフィルム / 歯周病原細菌 / 1型糖尿病 / HbA1c / 小児歯周病 / 糖尿病マウス / HbAlc / 硝酸メチル |
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| Research Abstract |
Type I diabetes mellitus occurs in an early stage of the childhood. The ratios of BOP+ children decreased from 96. 4% to 60%(p<0. 05). Also, in the DM group, the number of BOP showed a low value per person as compared with 2005DM group in 2011. Furthermore, we showed the tendency that the number of BOP increased with the increase of the HbA1c level. The intraoral bacteria rate of detection of A. a, P. g, P. i, T. d, T. f which were periodontal pathogenic bacteria were found little difference.
However, as for the rate of detection of T. f of the periodontal disease risk factor, T. f(approximately 95% of rate of detection) was higher in children with type I diabetes mellitus than healthy child(80% of rate of detection). Oral care for childhood type I diabetes mellitus improved an intraoral inflammatory state and suggested that it is important to the oral care to affection children
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