Technical developments for high S/N ratio of diffraction data in low energy SAD phasing
| Project/Area Number |
21687010
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Structural biochemistry
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| Research Institution | High Energy Accelerator Research Organization |
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Principal Investigator |
YAMADA Yusuke 大学共同利用機関法人高エネルギー加速器研究機構, 物質構造科学研究所, 助教 (20391708)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥24,050,000 (Direct Cost: ¥18,500,000、Indirect Cost: ¥5,550,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2010: ¥8,320,000 (Direct Cost: ¥6,400,000、Indirect Cost: ¥1,920,000)
Fiscal Year 2009: ¥13,520,000 (Direct Cost: ¥10,400,000、Indirect Cost: ¥3,120,000)
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| Keywords | X線結晶解析 / タンパク質結晶構造解析 / 低エネルギーSAD法 / 構造生物学 |
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| Research Abstract |
In this project, technical developments to measure weak anomalous signals in diffraction data for low energy SAD phasing method has been carried out. As results, a helium gas cryo-stream system and a helium gas substitution chamber has been made to decrease X-ray absorption effects around samples. In addition, automated data processing system which rapidly evaluates a level of anomalous signals in diffraction data has been developed.
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Report
(4 results)
Research Products
(15 results)
