Search for an aberrant splicing associated with schizophrenia specific antigen
| Project/Area Number |
21700385
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Nerve anatomy/Neuropathology
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| Research Institution | Fujita Health University |
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Principal Investigator |
MANABE Takayuki Fujita Health University, 総合医科学研究所, 講師 (90382283)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2009: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | 統合失調症 / リンパ芽球 / スクリーニング |
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| Research Abstract |
This research topic has aimed the comparative study of the difference of the production style of antibodies between the normal and the schizophrenia patients using the lymphoblastoid cell lines obtained from both groups. By this research topic, it has been demonstrated that the selectivity of J1-3 and J7 are different from the normal control in schizophrenia.
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Report
(3 results)
Research Products
(22 results)
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[Book] Protein, Nucleic Acid, Enzyme.2009
Author(s)
Mayeda A., Manabe T., Ohe K.
Total Pages
6
Publisher
Oncogenic HMGA1a protein causes Sporadic Alzheimer's disease-associated aberrant splicing : The molecular mechanism reveals a link with U1 snRNP-mediated gene repression system
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