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Development of Clathrate-type single-cell array chip using thermoresponsive polymer

Research Project

Project/Area Number 21700496
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Biomedical engineering/Biological material science
Research InstitutionToyama Industrial Technology Center,

Principal Investigator

YOKOYAMA Yoshiyuki  富山県工業技術センター, 機械電子研究所, 主任研究員 (60416154)

Project Period (FY) 2009 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords温度応答性高分子 / ゲル / 細胞アレイチップ / フォトリソグラフィー / ナノインプリント / バイオレジスト / 微細加工 / 細胞チップ / 1細胞操作 / 細胞モップ
Research Abstract

We developed Bio-resist by providing thermoresponsive polymer with photocrosslinking and thermal cross-linking capabilities. The Bio-resist can be used for micro fabrication by photolithography and thermal-nanoimprint. And small Bio-resist patterns could be changed reversibly by changing temperature. Moreover, we developed a clathrate-type single-cell array chip which consists of many arrays of Bio-resist hole patterns where small objects such as single-cells can be captured and released.

Report

(4 results)
  • 2012 Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (19 results)

All 2011 2010 2009 Other

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (14 results) Book (2 results) Remarks (1 results)

  • [Journal Article] Micro- and nano-fabrication of stimulus-responsive polymer using nanoimprint lithography2011

    • Author(s)
      Y. Yokoyama, M. Umezaki, T. Kishioka, E. Tamiya and Y. Takamura
    • Journal Title

      Journal of Photopolymer Science and Technology

      Volume: Vol.24 Pages: 63-70

    • NAID

      40019008720

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Micro- and nano-fabrication of stimulus-responsive polymer using nanoimprint lithography2011

    • Author(s)
      Y.Yokoyama, M.Umezaki, T.Kishioka, E.Tamiya, Y.Takamura
    • Journal Title

      Journal of Photopolymer Science and Technology

      Volume: 24 Pages: 63-70

    • NAID

      40019008720

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Presentation] Clathrate-type cell array chip that can freely capture, release and array cells using thermoresponsive gel2011

    • Author(s)
      Y.Yokoyama, M.Umezaki, T.Kishioka, Y.Takamura
    • Organizer
      International Conference on Biofabrication 2011 in TOYAMA
    • Place of Presentation
      富山国際会議場
    • Year and Date
      2011-10-06
    • Related Report
      2011 Annual Research Report
  • [Presentation] Micro- and nano-fabrication of stimulus-responsive polymer using nanoimprint lithography2011

    • Author(s)
      Y.Yokoyama, M.Umezaki, T.Kishioka, E.Tamiya, Y.Takamura
    • Organizer
      The 28th International Conference of Photopolymer Science and Technology (ICPST-28)
    • Place of Presentation
      千葉大学けやき会館
    • Year and Date
      2011-06-23
    • Related Report
      2011 Annual Research Report
  • [Presentation] 温度応答性ポリマーのバイオ応用2011

    • Author(s)
      横山義之
    • Organizer
      ナノインプリント技術の開発とその応用(主催:応用物理学会 北陸・信越支部)
    • Place of Presentation
      富山国際会議場(富山県)(招待講演)
    • Year and Date
      2011-01-13
    • Related Report
      2010 Annual Research Report
  • [Presentation]2011

    • Organizer
      International Conference on Biofabrication 2011
    • Place of Presentation
      TOYAMA
    • Related Report
      2012 Final Research Report
  • [Presentation] 刺激応答性ポリマーを用いたバイオチップ用レジストの開発2010

    • Author(s)
      横山義之
    • Organizer
      第56回高分子討論会
    • Place of Presentation
      北海道大学(北海道)
    • Year and Date
      2010-09-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] 温度応答性ポリマーのバイォ応用2010

    • Author(s)
      横山義之
    • Organizer
      第6回ナノインプリント技術研究会(招待講演)
    • Place of Presentation
      弘済会館(東京都)
    • Year and Date
      2010-03-05
    • Related Report
      2009 Annual Research Report
  • [Presentation] Development of micro-fabrication technology of thermal-responsive polymer using photolithography and nanoimprint method.2009

    • Author(s)
      横山義之
    • Organizer
      22nd International Microprocesses and Nanotechnology Conference
    • Place of Presentation
      シェラトン札幌(北海道)
    • Year and Date
      2009-11-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] ナノインプリント法を用いた温度応答性ポリマーの微細加工技術の開発2009

    • Author(s)
      横山義之
    • Organizer
      第70回応用物理学会学術講演会
    • Place of Presentation
      富山大学(富山県)
    • Year and Date
      2009-09-09
    • Related Report
      2009 Annual Research Report
  • [Presentation]

    • Organizer
      The 28th International Conference of Photopolymer Science and Technology (ICPST-28)
    • Related Report
      2012 Final Research Report
  • [Presentation] ナノインプリント技術の開発とその応用

    • Organizer
      応用物理学会 北陸・信越支部セミナー(招待講演)
    • Related Report
      2012 Final Research Report
  • [Presentation]

    • Organizer
      第6回ナノインプリント技術研究会(応用物理学会)(招待講演)
    • Related Report
      2012 Final Research Report
  • [Presentation]

    • Organizer
      第56回高分子討論会(依頼講演)
    • Related Report
      2012 Final Research Report
  • [Presentation]

    • Organizer
      22nd International Microprocesses and Nanotechnology Conference
    • Related Report
      2012 Final Research Report
  • [Presentation]

    • Organizer
      第70回 応用物理学会 学術講演会
    • Related Report
      2012 Final Research Report
  • [Book] ナインプリントの開発とデバイス応用2011

    • Author(s)
      横山義之、他
    • Publisher
      シーエムシー出版
    • Related Report
      2012 Final Research Report
  • [Book] コンバーテック2009

    • Author(s)
      横山義之、他
    • Total Pages
      64
    • Publisher
      加工技術研究会
    • Related Report
      2012 Final Research Report
  • [Remarks] (所属機関HP)

    • URL

      http://www.itc.pref.toyama.jp/

    • Related Report
      2012 Final Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

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