Intestinal tract dysfunction and skeletal muscle regeneration mechanism
Project/Area Number |
21700687
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Applied health science
|
Research Institution | Ritsumeikan University (2010-2011) Tohoku University (2009) |
Principal Investigator |
MATSUO Kaori 立命館大学, スポーツ健康科学部, 助教 (60513570)
|
Project Period (FY) |
2009 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
Keywords | スポーツ免疫学 / 腸内細菌 / 骨格筋損傷 / 腸管機能 / 免疫組織化学染色法 |
Research Abstract |
To investigate the contribution of commensal bacteria to the recovery of damaged skeletal muscle. It was examined whether probiotics administration may facilitate recovery of skeletal muscle tissue from damage in older animals in which muscle regeneration is compromised. These results suggest that components of commensal bacterial such as LPS favor the recovery of skeletal muscle from muscle damage. Moreover, probiotics favor the recovery of skeletal muscle from muscle damage in older adult mouse.
|
Report
(4 results)
Research Products
(24 results)