| Project/Area Number |
21700761
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Eating habits, studies on eating habits
|
|---|
| Research Institution | University of Shizuoka |
|---|
Principal Investigator |
SAKAKIBARA Hiroyuki University of Shizuoka, 環境科学研究所, 助教 (20403701)
|
|---|
| Research Collaborator |
SHIMOI Kayoko 静岡県立大学, 環境科学研究所, 教授 (10162728)
|
|---|
| Project Period (FY) |
2009 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
|---|
| Keywords | 健康と食生活 / ストレス性肥満 / 食品由来因子 / プレバイオマーカー / 心理・社会的ストレス / PAI-1 / バイオマーカー / 概日リズム / 睡眠・覚醒サイクル / マウス / 肝肥大 / ビルベリーアントシアニン / サーカディアンリズム |
|---|
| Research Abstract |
Mice were singly housed with reduced bed-volume for 3 months. Their body and visceral fat weights were significantly increased in combination with hepatic hypertrophy because of lipid deposition comparing to the control (5 mice/cage). The alterations of blood creatine kinase and plasminogen activator inhibitor type 1 (PAI-1) levels were suggested to might be used as pre-biomarker for social stress-inducible obesity. Additionally, PAI-1 increased under stressful events might not affect on sleep disturbance.
|
