Influence on the raise of blood glucose and insulin secretion by AMP oral ingestion

• Project/Area Number: 21700766
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Eating habits, studies on eating habits
• Research Institution: Kyoto Women's University (2011); Yasuda Women's University (2009-2010)
• Principal Investigator: KIYAMA Atsuko 京都女子大学, 家政学部, 講師 (70405504)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000); Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
• Keywords: 栄養生理 / 栄養補助成分 / AMP

Research Abstract

AMP activated kinase(AMPK) is a enzyme that plays a important role in cellular energy homeostasis. In this study, I examined the oral ingestion of AMP which is the substrate of AMPK, effect on the raise of blood glucose and insulin secretion in the mice, and the glucose uptake to IEC-6 cell from medium with AMP+/-. But in this experiment, the difference of AMP(+) or(-) does not become clear.