Development of mesoporous silica for removal of middle molecule uremic toxins
| Project/Area Number |
21760527
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Inorganic materials/Physical properties
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| Research Institution | Tohoku University |
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Principal Investigator |
HOSHIKAWA Yasuto Tohoku University, 多元物質科学研究所, 助教 (90527839)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2009: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | ナノ材料 / 生体材料 / メソポーラスシリカ / 炭素被覆 / 多孔性材料 / 炭素材料 |
|---|
| Research Abstract |
Selective removal of middle molecule uremic toxins is difficult in a current hemodialysis membrane. Mesoporous silica nanoparticles (MSNs) are promising as superior adsorbent for specific middle molecule with highly selectivity. Expansion of mesopore (over 6nm, the size is well suited to absorbing middle molecule) in MSNs was achieved by adding 1,3,5-trimethylbenzene and incorporating aminopropyl group in silica structure, and the silica surface of MSNs was coated by carbon thin layer (under 1nm) to improve blood compatibility and durability.
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Report
(3 results)
Research Products
(24 results)
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[Journal Article] Enhancement of Corrosion Resistance of Titanium-Copper Based Metallic Glass by Methylsiloxane Coating2009
Author(s)
Yasuto Hoshikawa, Eiichi Yasuda, Takashi Akatsu, Toru Onoda, Naota Sugiyama, Nobuhiro Matsushita, Takamasa Onoki, Masaru Akao, Yasuhiro Tanabe, Masahiro Yoshimura, Shengli Zhu, Xinmin Wang, Akihisa Inoue
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Journal Title
Materials Transactions 50
Pages: 52-58
NAID
Related Report
Peer Reviewed
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[Presentation] カーボンナノ試験管のナノ空間内でのDNA濃縮2010
Author(s)
干川康人, 寒河江拓也, 菅野康之, 折笠広典, Somlak Ittisanronnach, 井本修平, 和田健彦, 永次史, 京谷隆
Organizer
2010高分子・ハイブリッド材料研究センター若手フォーラム
Place of Presentation
東北大学片平さくらホール(仙台)
Year and Date
2010-12-06
Related Report
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