STUDY OF THE INTERACTION BETWEEN ELUTING HEAVY METALS AND CYTOTOXICITY BY HUMAN CULTURED CELLULAR ASSAY
| Project/Area Number |
21760600
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Metal making engineering
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| Research Institution | Suzuka National College of Technology |
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Principal Investigator |
OGAWA Akiko Suzuka National College of Technology, 生物応用化学科, 助教 (90455139)
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| Research Collaborator |
KANEMATSU Hideyuki 鈴鹿工業高等専門学校, 材料工学科, 教授 (10185952)
TAMAUCHI Hidekazu 北里大学, 医学部, 助教 (60188414)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
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| Keywords | めっき加工材料 / 生体機能 / 溶出特性 / めっき加工 / 金属腐食 |
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| Research Abstract |
This study has aimed to clarify the influence of the surface conditions and the characteristic change of the plating on the biological functions. I developed the in vitro assay system using human cultured cells and I examined the change of cellular functions when the cells were treated with the plating. Changing the surface condition of plating not only influenced the feature of elution but also induced the change in the cellular functions.
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Report
(3 results)
Research Products
(46 results)
