Analysis of the novel nitrogen metabolism in Streptomyces.

Research Project

Project/Area Number	21780081
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Applied microbiology
Research Institution	Tokyo University of Agriculture
Principal Investigator	SASAKI Yasuyuki Tokyo University of Agriculture, 応用生物科学部, 助教 (50398814)
Project Period (FY)	2009 – 2010
Project Status	Completed (Fiscal Year 2010)
Budget Amount *help	¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000) Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000) Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords	遺伝学 / 酵素学 / 窒素代謝 / 応用微生物 / 放線菌
Research Abstract	We analyzed physiological roles of aerobic membrane-binding type nitrate reductase (dNar) and nitric oxide dioxygenase (flavohemoglobin) in Streptomyces coelicolor. As a result, the dNar destruption caused abnormality to the antibiotic production compared with that of a wild type. Moreover, the influence also appeared for the secondary metabolism in the flavohemoglobin destruptant.

Report

(3 results)