Proteomic analysis of sperm releasing proteins during capacitation
Project/Area Number |
21790084
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Biological pharmacy
|
Research Institution | Kumamoto University |
Principal Investigator |
TAKEO Toru Kumamoto University, 生命資源研究・支援センター, 助教 (10517014)
|
Project Period (FY) |
2009 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
|
Keywords | 受精 / 精子 / シクロデキストリン / プロテオミクス / 受精能獲得 / マウス |
Research Abstract |
We have developed a new technology of proteomics with high sensitivity for detecting trace of proteins released from mouse sperm during capacitation. Novel proteins derived from sperm were identified using the system. These findings suggested that identified proteins have potential to regulate the sperm functions which are useful to understand the mechanism of fertility control in sperm via the proteins.
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Report
(3 results)
Research Products
(9 results)