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Proteomic analysis of sperm releasing proteins during capacitation

Research Project

Project/Area Number 21790084
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Biological pharmacy
Research InstitutionKumamoto University

Principal Investigator

TAKEO Toru  Kumamoto University, 生命資源研究・支援センター, 助教 (10517014)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords受精 / 精子 / シクロデキストリン / プロテオミクス / 受精能獲得 / マウス
Research Abstract

We have developed a new technology of proteomics with high sensitivity for detecting trace of proteins released from mouse sperm during capacitation. Novel proteins derived from sperm were identified using the system. These findings suggested that identified proteins have potential to regulate the sperm functions which are useful to understand the mechanism of fertility control in sperm via the proteins.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (9 results)

All 2011 2010 2009 Other

All Presentation (5 results) Remarks (4 results)

  • [Presentation] プロテオミクスにより明らかになったマウス精子の系統特異的なタンパク質発現パターン2011

    • Author(s)
      竹尾透、三池浩一郎、今中応亘、三池輝久、山村研一、中潟直己
    • Organizer
      日本薬学会131年会
    • Place of Presentation
      静岡、ツインメッセ静岡
    • Year and Date
      2011-03-31
    • Related Report
      2010 Final Research Report
  • [Presentation] プロテオミクスにより明らかになったマウス精子の系統特異的なタン、パク質発現パターン2011

    • Author(s)
      竹尾透
    • Organizer
      日本薬学会131年会
    • Place of Presentation
      ツインメッセ静岡、静岡
    • Year and Date
      2011-03-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] プロテオミクス手法を利用したマウス精子の系統間比較2010

    • Author(s)
      竹尾透、三池浩一郎、今中応亘、三池輝久、山村研一、中潟直己
    • Organizer
      第57回日本実験動物学会
    • Place of Presentation
      京都、京都テルサ
    • Year and Date
      2010-05-15
    • Related Report
      2010 Final Research Report
  • [Presentation] マウス精子のプロテオミクス2009

    • Author(s)
      竹尾透
    • Organizer
      第23回動物生殖工学研究会
    • Place of Presentation
      北里大学(東京都)
    • Year and Date
      2009-12-05
    • Related Report
      2009 Annual Research Report
  • [Presentation] マウス精子のプロテオミクス2009

    • Author(s)
      竹尾透、三池浩一郎、今中応亘、三池輝久、山村研一、中潟直己
    • Organizer
      第23回動物生殖工学研究会
    • Place of Presentation
      東京、北里大学
    • Related Report
      2010 Final Research Report
  • [Remarks] ホームページ等

    • Related Report
      2010 Final Research Report
  • [Remarks] 当研究室HP

    • URL

      http://card.medic.kumamoto-u.ac.jp/card/japanese/kenkyu/sigen/index.html

    • Related Report
      2010 Final Research Report
  • [Remarks]

    • URL

      http://card.medic.kumamoto-u.ac.jp/card/japanese/kenkyu/sigen/index.html

    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://card.medic.kumamoto-u.ac.jp/card/japanese/kenkyu/sigen/gakkai/index.html

    • Related Report
      2009 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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