| Project/Area Number |
21790292
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
General medical chemistry
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| Research Institution | Tokyo University of Pharmacy and Life Science |
|---|
Principal Investigator |
NAKAMURA Yoshikazu Tokyo University of Pharmacy and Life Science, 生命科学部, 講師 (60366416)
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|---|
| Project Period (FY) |
2009 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 毛形成 / ホスホリパーゼC / FOXN1 / Notch |
|---|
| Research Abstract |
A transcription factor, FOXN1 is essential for hair formation. Phospholipase C (PLC)δ1, a key molecule in the phosphoinositide signaling pathway, is essential for normal hair formation. In this study, we found that Foxn1-mediated expression of PLCδ1 is important in normal hair formation and Notchl expression.
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