| Project/Area Number |
21790300
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
General medical chemistry
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| Research Institution | Research Institute, International Medical Center of Japan |
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Principal Investigator |
HIKICHI Takafusa 国立国際医療研究センター, 細胞組織再生医学研究部, 上級研究員 (80392083)
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| Project Period (FY) |
2009 – 2010
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 単為発生 / ゲノミックインプリンティング / 核移植 / 胎盤形成 / 胚発生 / 幹細胞 |
|---|
| Research Abstract |
Although siRNA to the gene which the amount of expression increased before and after the nuclear transplantation was introduced into the normal fertilized embryo nature stem cell (ES), respectively, change of the differentiation ability to the nerve cell in in vitro was not observed. And the placentas of parthenogenetic embryos can escape epigenetic regulation when developed using nuclear transfer techniques and can support fetal development to full gestation.
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