| Project/Area Number |
21790637
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
General internal medicine (including Psychosomatic medicine)
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| Research Institution | University of Occupational and Environmental Health, Japan |
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Principal Investigator |
MERA Takashi University of Occupational and Environmental Health, Japan, 医学部, 助教 (20533053)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 六君子湯 / 悪液質 / 東洋医学 / 急性炎症 / 食欲不振 / 体重減少 / 漢方薬 / リポポリサッカライド |
|---|
| Research Abstract |
Our purpose is to evaluate the effects of Rikkunshito on the cachexia-anorexia syndrome. At first, we investigated the effects of Rikkunshito on the lipopolysaccharide (LPS)-induced anorexia in rats. LPS-induced anorexia was not reversed by Rikkunshito. Secondary, we investigated effects of Rikkunshito on another stress-induced anorexia model. Restraint stress-induced anorexia was partially reversed by Rikkunshito.
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