A pathological study of the Aquaporin 4 associated disease Neuromyelitis Optica
| Project/Area Number |
21790829
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Neurology
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| Research Institution | Tohoku University |
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Principal Investigator |
MISU Tatsuro Tohoku University, 大学院・医学系研究科, 助教 (00396491)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | 視神経脊髄炎 / 多発性硬化症 / アクアポリン4抗体 / アストロサイト / GFAP / アクアポリン4 / オリゴデンドロサイト / 脱髄 / 神経病理 / 神経免疫 |
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| Research Abstract |
We revealed that anti-AQP4 antibody was pathogenic in vitro and in vivo, and we reported several papers to suggest the clinical features, clinical biomarkers, or therapeutic strategy related to aquaporin 4 autoimmunity of neuromyelitis optica.
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Report
(3 results)
Research Products
(43 results)
